Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SNORA53 Gene

Subcategory (RNA class) for SNORA53 Gene


Quality Score for this RNA gene is


Aliases for SNORA53 Gene

  • Small Nucleolar RNA, H/ACA Box 53 2 3 5
  • ACA53 3

External Ids for SNORA53 Gene

Previous GeneCards Identifiers for SNORA53 Gene

  • GC12P097517
  • GC12P098993
  • GC12P096054

Summaries for SNORA53 Gene

GeneCards Summary for SNORA53 Gene

SNORA53 (Small Nucleolar RNA, H/ACA Box 53) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA53 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

Additional gene information for SNORA53 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA53 Gene

Genomics for SNORA53 Gene

GeneHancer (GH) Regulatory Elements for SNORA53 Gene

Promoters and enhancers for SNORA53 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I098635 Enhancer 0.8 ENCODE 10.9 +36.6 36550 0.9 PKNOX1 JUN INSM2 PAX8 FEZF1 BATF ZEB1 ZNF366 ZSCAN5C ATF7 PPIAP8 SLC25A3 SNORA53 IKBIP GC12M098601
GH12I098532 Enhancer 0.8 ENCODE 10.4 -66.1 -66057 1.8 HDAC1 PKNOX1 ARNT RAD21 ZNF766 ZNF143 ATF7 SMARCA5 RXRA CEBPB RNU4-41P LINC02453 SNORA53 IKBIP APAF1 SLC9A7P1 GC12M098524 GC12M098549 TMPO
GH12I098654 Enhancer 0.7 ENCODE 11.3 +54.5 54453 0.1 CTCF FOXA2 ARID4B RAD21 RFX5 FOXK2 ZNF143 SMC3 MIXL1 SMARCA5 GC12M098651 SNORA53 RNU4-41P LINC02453 IKBIP GC12P098649 APAF1
GH12I098648 Promoter 0.6 EPDnew 10.4 +48.8 48754 0.1 MITF APAF1 GC12P098649 SNORA53 RNU4-41P
GH12I098351 Enhancer 0.9 Ensembl ENCODE 4.8 -246.9 -246893 2.2 ZBTB21 JUN EBF1 IRF4 ZBTB40 ZEB1 ATF7 FOSL2 FOS IKZF2 SNORA53 LOC105369933 GC12P098384
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORA53 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA53 gene promoter:

Genomic Locations for SNORA53 Gene

Genomic Locations for SNORA53 Gene
250 bases
Plus strand

Genomic View for SNORA53 Gene

Genes around SNORA53 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA53 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA53 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA53 Gene

ORGUL Member Location for SNORA53 Gene

ORGUL Member Location for SNORA53 gene

Proteins for SNORA53 Gene

Post-translational modifications for SNORA53 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA53 Gene

Domains & Families for SNORA53 Gene

Gene Families for SNORA53 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA53: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA53 Gene

Function for SNORA53 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA53 Gene

Localization for SNORA53 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA53 Gene

Pathways & Interactions for SNORA53 Gene

SuperPathways for SNORA53 Gene

No Data Available

Interacting Proteins for SNORA53 Gene

Gene Ontology (GO) - Biological Process for SNORA53 Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA53 Gene

Drugs & Compounds for SNORA53 Gene

No Compound Related Data Available

Transcripts for SNORA53 Gene

mRNA/cDNA for SNORA53 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA53 Gene

No ASD Table

Relevant External Links for SNORA53 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA53 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA53 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA53 Gene:


SOURCE GeneReport for Unigene cluster for SNORA53 Gene:

genes like me logo Genes that share expression patterns with SNORA53: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA53 Gene

Orthologs for SNORA53 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA53 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA53 34
  • 100 (a)
(Bos Taurus)
Mammalia SNORA53 34
  • 94 (a)
(Canis familiaris)
Mammalia SNORA53 34
  • 91 (a)
(Mus musculus)
Mammalia Gm24119 34
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA53 34
  • 84 (a)
(Monodelphis domestica)
Mammalia SNORA53 34
  • 83 (a)
(Gallus gallus)
Aves SNORA53 34
  • 76 (a)
(Anolis carolinensis)
Reptilia SNORA53 34
  • 74 (a)
(Danio rerio)
Actinopterygii SNORA53 34 34
  • 51 (a)
Species where no ortholog for SNORA53 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA53 Gene

Gene Tree for SNORA53 (if available)
Gene Tree for SNORA53 (if available)

Paralogs for SNORA53 Gene

No data available for Paralogs for SNORA53 Gene

Variants for SNORA53 Gene

Sequence variations from dbSNP and Humsavar for SNORA53 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs11544648 benign, likely-benign, not specified, Mitochondrial phosphate carrier deficiency 98,598,012(+) T/C upstream_transcript_variant
rs200029342 uncertain-significance, Mitochondrial phosphate carrier deficiency 98,600,132(+) G/A/C/T downstream_transcript_variant
rs531425336 uncertain-significance, likely-benign, Mitochondrial phosphate carrier deficiency, not specified 98,598,533(+) T/C upstream_transcript_variant
rs772819565 uncertain-significance, Mitochondrial phosphate carrier deficiency 98,600,028(+) C/T downstream_transcript_variant
rs886049920 uncertain-significance, Mitochondrial phosphate carrier deficiency 98,600,131(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA53 Gene

Variant ID Type Subtype PubMed ID
nsv559918 CNV loss 21841781
nsv7234 OTHER inversion 18451855

Additional Variant Information for SNORA53 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA53 Gene

Disorders for SNORA53 Gene

Additional Disease Information for SNORA53

No disorders were found for SNORA53 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA53 Gene

Publications for SNORA53 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 58
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 58
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  4. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
  5. RNAdb--a comprehensive mammalian noncoding RNA database. (PMID: 15608161) Pang KC … Mattick JS (Nucleic acids research 2005) 1

Products for SNORA53 Gene

Sources for SNORA53 Gene

Loading form....