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Aliases for SNORA52 Gene

Subcategory (RNA class) for SNORA52 Gene

snoRNA

Quality Score for this RNA gene is

13

Aliases for SNORA52 Gene

  • Small Nucleolar RNA, H/ACA Box 52 2 3 5
  • ACA52 Small Nucleolar RNA 3
  • ACA52 SnoRNA 3
  • ACA52 3

External Ids for SNORA52 Gene

Previous GeneCards Identifiers for SNORA52 Gene

  • GC11P000803
  • GC11P000629

Summaries for SNORA52 Gene

GeneCards Summary for SNORA52 Gene

SNORA52 (Small Nucleolar RNA, H/ACA Box 52) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORA52 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA52 Gene

Genomics for SNORA52 Gene

GeneHancer (GH) Regulatory Elements for SNORA52 Gene

Promoters and enhancers for SNORA52 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J000803 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 47.3 -3.0 -2955 10.7 HDGF ZFX ZNF652 SP1 CC2D1A ELF3 MNT SIX5 ZNF148 NKRF RPLP2 PIDD1 TMEM80 PHRF1 ENSG00000255108 SNORA52 ENSG00000255237 BET1L TSPAN4 PSMD13
GH11J000839 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 29.6 +32.1 32100 7.6 HDGF MTA3 SP1 ELF3 ZFX MNT SIX5 ZNF148 NKRF POLR2A TSPAN4 POLR2L GC11M000841 CD151 TMEM80 PIDD1 SNORA52 RPLP2 ENSG00000255237 RIC8A
GH11J000324 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 20.4 -483.8 -483785 7.8 SP1 ELF3 CC2D1A ZKSCAN8 CBFA2T2 ZNF148 NKRF MLLT1 GTF2F1 ZNF687 ENSG00000270030 ENSG00000255328 IFITM3 LOC105376504 TMEM80 TSPAN4 ENSG00000251661 RIC8A PHRF1 SNORA52
GH11J001015 Enhancer 0.8 Ensembl 56.4 +205.4 205380 3.3 ZNF548 ZNF680 ZNF560 CREB1 GLIS2 REST ZNF776 ATF7 ZNF148 FOXK2 PHRF1 TMEM80 PIDD1 SNORA52 TSPAN4 ENSG00000255237 ENSG00000255142 BET1L RNH1 RIC8A
GH11J000443 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 16.8 -364.0 -363979 8.6 HDGF ZNF652 SP1 CC2D1A ZFX ELF3 CTCF MNT SIX5 CBFA2T2 PTDSS2 RNH1 LRRC56 TSPAN4 SNORA52 PHRF1 ENSG00000255237 ANO9 HRAS BET1L
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORA52 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA52 gene promoter:
  • HEN1
  • NF-kappaB
  • NF-kappaB1
  • p300
  • p53
  • Pax-5
  • RelA
  • YY1

Genomic Locations for SNORA52 Gene

Genomic Locations for SNORA52 Gene
chr11:811,681-811,814
(GRCh38/hg38)
Size:
134 bases
Orientation:
Plus strand
chr11:811,681-811,814
(GRCh37/hg19)
Size:
134 bases
Orientation:
Plus strand

Genomic View for SNORA52 Gene

Genes around SNORA52 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA52 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA52 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA52 Gene

Proteins for SNORA52 Gene

Post-translational modifications for SNORA52 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA52 Gene

Domains & Families for SNORA52 Gene

Gene Families for SNORA52 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA52: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA52 Gene

Function for SNORA52 Gene

Phenotypes From GWAS Catalog for SNORA52 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA52 Gene

Localization for SNORA52 Gene

Gene Ontology (GO) - Cellular Components for SNORA52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORA52: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SNORA52 Gene

Pathways & Interactions for SNORA52 Gene

PathCards logo

SuperPathways for SNORA52 Gene

No Data Available

Interacting Proteins for SNORA52 Gene

Gene Ontology (GO) - Biological Process for SNORA52 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORA52: view

No data available for Pathways by source and SIGNOR curated interactions for SNORA52 Gene

Drugs & Compounds for SNORA52 Gene

No Compound Related Data Available

Transcripts for SNORA52 Gene

mRNA/cDNA for SNORA52 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNA Central transcripts :

Unigene Clusters for SNORA52 Gene

Small nucleolar RNA, H/ACA box 52:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA52 Gene

No ASD Table

Relevant External Links for SNORA52 Gene

GeneLoc Exon Structure for
SNORA52
ECgene alternative splicing isoforms for
SNORA52

Expression for SNORA52 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA52 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA52 Gene:

SNORA52

SOURCE GeneReport for Unigene cluster for SNORA52 Gene:

Hs.689713
genes like me logo Genes that share expression patterns with SNORA52: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA52 Gene

Orthologs for SNORA52 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA52 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA52 35
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA52 35
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA52 35
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA52 35 35
  • 69 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Snora52 35
  • 66 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA52 35
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORA52 35
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORA52 35
  • 51 (a)
OneToOne
Species where no ortholog for SNORA52 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORA52 Gene

ENSEMBL:
Gene Tree for SNORA52 (if available)
TreeFam:
Gene Tree for SNORA52 (if available)

Paralogs for SNORA52 Gene

No data available for Paralogs for SNORA52 Gene

Variants for SNORA52 Gene

Sequence variations from dbSNP and Humsavar for SNORA52 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000118985 -- 811,147(+) A/G upstream_transcript_variant
rs1000267176 -- 809,693(+) G/A/C upstream_transcript_variant
rs1000272107 -- 811,007(+) C/A upstream_transcript_variant
rs1001051325 -- 810,435(+) A/C upstream_transcript_variant
rs1001497843 -- 810,207(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA52 Gene

Variant ID Type Subtype PubMed ID
dgv1013n100 CNV gain 25217958
dgv182e199 CNV deletion 23128226
esv2759794 CNV loss 17122850
nsv1040044 CNV gain+loss 25217958
nsv1159791 CNV deletion 26073780
nsv469923 CNV loss 18288195
nsv552871 CNV loss 21841781
nsv832044 CNV loss 17160897
nsv8759 CNV gain 18304495
nsv951272 CNV deletion 24416366

Additional Variant Information for SNORA52 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA52

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA52 Gene

Disorders for SNORA52 Gene

Additional Disease Information for SNORA52

No disorders were found for SNORA52 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA52 Gene

Publications for SNORA52 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 58
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 58
  3. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3 58
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORA52 Gene

Sources for SNORA52 Gene

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