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Aliases for SNORA3B Gene

Subcategory (RNA class) for SNORA3B Gene


Quality Score for this RNA gene is


Aliases for SNORA3B Gene

  • Small Nucleolar RNA, H/ACA Box 3B 2 3 5
  • Small Nucleolar RNA, H/ACA Box 45B 2 3
  • Small Nucleolar RNA, H/ACA Box 45 2 3
  • ACA3-2 SnoRNA 3
  • SNORA45B 3
  • SNORA45 3
  • ACA3-2 3

External Ids for SNORA3B Gene

Previous HGNC Symbols for SNORA3B Gene

  • SNORA45
  • SNORA45B

Previous GeneCards Identifiers for SNORA3B Gene

  • GC11P008696
  • GC11P008701
  • GC11P008708
  • GC11P008711
  • GC11P008716

Summaries for SNORA3B Gene

Entrez Gene Summary for SNORA3B Gene

  • Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA45, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORA3B Gene

SNORA3B (Small Nucleolar RNA, H/ACA Box 3B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA3B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • Small nucleolar RNA SNORA3/SNORA45 family: The members of this family belong to the H/ACA class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines [1]. This family includes mouse snoMBI-28 and human homologues ACA3 (SNORA3) and ACA3-2 (SNORA45). Both ACA3 and ACA3-2 share the same host gene [3]. MBI-28, ACA3 and ACA3-2 are all predicted to guide the pseudouridylation of residues in 28S rRNA [1,2,3].

View fRNAdb secondary structures for SNORA3B

Additional gene information for SNORA3B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA3B Gene

Genomics for SNORA3B Gene

GeneHancer (GH) Regulatory Elements for SNORA3B Gene

Promoters and enhancers for SNORA3B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I008681 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 618.7 +0.4 416 8.7 MLX DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC SNORA3B RPL27A GC11P008722 GC11P008723 GC11P008725 GC11P008726 GC11P008728 GC11P008729 PIR32700 PIR61800
GH11I009458 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 46.5 +776.0 775960 5 ZFP64 DMAP1 IRF4 YY1 E2F8 ZNF143 SP3 NFYC MEF2D GLIS1 ZNF143 LOC644656 SNORA3B RPL21P97 RPL27A TMEM9B-AS1 WEE1 IPO7 GC11P009430 PIR40365
GH11I009564 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 35.9 +886.8 886809 15.2 CLOCK MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 WEE1 SNORA3B SWAP70 ZNF143 TRIM66 RPL21P97 AKIP1 TMEM41B DENND5A ENSG00000238387
GH11I007985 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 44.3 -698.3 -698250 2.7 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 EIF3F SNORA3B OLFML1 TMEM9B-AS1 ZNF214 RPL27A ST5 CASC23 TUB PIR63023
GH11I009383 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 27.5 +699.9 699868 3.1 HDGF PKNOX1 SMAD1 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 IPO7 SNORA3B ZNF143 RPL27A RPL21P97 GC11P009428
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORA3B on UCSC Golden Path with GeneCards custom track

Genomic Locations for SNORA3B Gene

Genomic Locations for SNORA3B Gene
131 bases
Plus strand

Genomic View for SNORA3B Gene

Genes around SNORA3B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA3B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA3B Gene

ORGUL Member Location for SNORA3B Gene

ORGUL Member Location for SNORA3B gene

Proteins for SNORA3B Gene

Post-translational modifications for SNORA3B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA3B Gene

Domains & Families for SNORA3B Gene

Gene Families for SNORA3B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA3B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA3B Gene

Function for SNORA3B Gene

Phenotypes From GWAS Catalog for SNORA3B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA3B Gene

Localization for SNORA3B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA3B Gene

Pathways & Interactions for SNORA3B Gene

SuperPathways for SNORA3B Gene

No Data Available

Interacting Proteins for SNORA3B Gene

Gene Ontology (GO) - Biological Process for SNORA3B Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA3B Gene

Drugs & Compounds for SNORA3B Gene

No Compound Related Data Available

Transcripts for SNORA3B Gene

fRNAdb Secondary structures for SNORA3B Gene

  • FR229415

mRNA/cDNA for SNORA3B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA3B Gene

No ASD Table

Relevant External Links for SNORA3B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA3B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA3B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA3B Gene

Orthologs for SNORA3B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA3B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA3 34
  • 100 (a)
(Canis familiaris)
Mammalia SNORA3 34
  • 88 (a)
(Monodelphis domestica)
Mammalia SNORA3 34
  • 75 (a)
(Mus musculus)
Mammalia Gm25539 34
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA3 34 34
  • 73 (a)
(Bos Taurus)
Mammalia SNORA3 34
  • 66 (a)
(Gallus gallus)
Aves SNORA3 34
  • 64 (a)
(Danio rerio)
Actinopterygii SNORA3 34 34 34 34
  • 69 (a)
Species where no ortholog for SNORA3B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA3B Gene

Gene Tree for SNORA3B (if available)
Gene Tree for SNORA3B (if available)

Paralogs for SNORA3B Gene

No data available for Paralogs for SNORA3B Gene

Variants for SNORA3B Gene

Sequence variations from dbSNP and Humsavar for SNORA3B Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1001394543 -- 8,684,284(+) G/A upstream_transcript_variant
rs1002378478 -- 8,685,051(+) G/C upstream_transcript_variant
rs1003447583 -- 8,685,994(+) G/A downstream_transcript_variant
rs1003957078 -- 8,683,743(+) T/C upstream_transcript_variant
rs1004506457 -- 8,685,356(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA3B Gene

Variant ID Type Subtype PubMed ID
nsv499766 OTHER inversion 21111241
nsv7215 OTHER inversion 18451855
nsv975880 CNV duplication 23825009

Additional Variant Information for SNORA3B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA3B Gene

Disorders for SNORA3B Gene

No disorders were found for SNORA3B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA3B Gene

Publications for SNORA3B Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 1 2 3 58
  2. A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. (PMID: 16361266) Gu AD … Qu LH (Nucleic acids research 2005) 1 2 3 58
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  5. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3

Products for SNORA3B Gene

Sources for SNORA3B Gene

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