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Aliases for SNORA30 Gene

Subcategory (RNA class) for SNORA30 Gene


Quality Score for this RNA gene is


Aliases for SNORA30 Gene

  • Small Nucleolar RNA, H/ACA Box 30 2 3 5
  • ACA30 SnoRNA 3
  • SNORA30A 3
  • ACA30 3

External Ids for SNORA30 Gene

Previous GeneCards Identifiers for SNORA30 Gene

  • GC16P030631
  • GC16P030721
  • GC16P028284

Summaries for SNORA30 Gene

GeneCards Summary for SNORA30 Gene

SNORA30 (Small Nucleolar RNA, H/ACA Box 30) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORA30 include Floating-Harbor Syndrome.

fRNAdb sequence ontologies for SNORA30 Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA30/SNORA37 family: The members of this family belong to the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines [1]. This family includes human ACA30 (SNORA30), ACA37 (SNORA37) and the mouse homolog MBI-26 [1,2]. Both ACA37 and ACA30 are predicted to guide the pseudouridylation of residue U4643 of 28S rRNA [3].

Additional gene information for SNORA30 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA30 Gene

Genomics for SNORA30 Gene

GeneHancer (GH) Regulatory Elements for SNORA30 Gene

Promoters and enhancers for SNORA30 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J030739 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 12.3 +30.5 30531 3.3 MAFK MYC SP1 PRDM1 HDGF FOSL2 CEBPG GLIS2 RFX1 ZNF600 ENSG00000260899 TMEM265 SNORA30 SRCAP PHKG2 ENSG00000282034
GH16J030774 Promoter/Enhancer 1.6 Ensembl ENCODE 11.1 +66.6 66553 5.5 HDGF ZFX ELF3 MNT SIX5 ZNF148 NKRF POLR2A MLLT1 CEBPG ENSG00000280211 GC16P030778 ZNF785 SRCAP ZNF720 SETD1A NPIPB13 CCDC189 KAT8 ZNF764
GH16J030939 Promoter/Enhancer 1.4 Ensembl ENCODE 10.3 +231.0 230999 3.6 HDGF CC2D1A CTCF ZSCAN21 SP7 SP5 KLF14 RAD21 GLIS2 RXRA HSD3B7 ZNF668 TGFB1I1 KAT8 SETD1A ZNF646 MIR762 CTF1 BCL7C CCDC189
GH16J030805 Enhancer 1.1 ENCODE 10.8 +95.8 95780 2.6 CC2D1A SP1 ZNF652 ZFX ELF3 MNT SIX5 POLR2A MLLT1 CEBPG SRCAP SETD1A ENSG00000260267 INO80E SMG1P5 RNF40 FUS ZNF764 ENSG00000260304 ZNF720
GH16J030796 Enhancer 1 Ensembl ENCODE 11.2 +86.6 86557 0.8 SP7 ZNF600 CEBPA ZNF629 ZNF692 CEBPB SCRT2 JUN RCOR1 ZSCAN5C NPIPB13 C16orf58 ENSG00000260267 ENSG00000261474 CCDC189 RNF40 SNORA30 SRCAP SETD1A INO80E
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORA30 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA30 gene promoter:
  • AML1a
  • c-Myb
  • C/EBPalpha
  • CHOP-10
  • Evi-1
  • HEN1
  • RORalpha2
  • YY1

Genomic Locations for SNORA30 Gene

Genomic Locations for SNORA30 Gene
129 bases
Plus strand
129 bases
Plus strand

Genomic View for SNORA30 Gene

Genes around SNORA30 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA30 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA30 Gene

ORGUL Member Location for SNORA30 Gene

ORGUL Member Location for SNORA30 gene

Proteins for SNORA30 Gene

Post-translational modifications for SNORA30 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA30 Gene

Domains & Families for SNORA30 Gene

Gene Families for SNORA30 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA30: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA30 Gene

Function for SNORA30 Gene

Phenotypes From GWAS Catalog for SNORA30 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA30 Gene

Localization for SNORA30 Gene

Gene Ontology (GO) - Cellular Components for SNORA30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORA30: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SNORA30 Gene

Pathways & Interactions for SNORA30 Gene

PathCards logo

SuperPathways for SNORA30 Gene

No Data Available

Interacting Proteins for SNORA30 Gene

Gene Ontology (GO) - Biological Process for SNORA30 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORA30: view

No data available for Pathways by source and SIGNOR curated interactions for SNORA30 Gene

Drugs & Compounds for SNORA30 Gene

No Compound Related Data Available

Transcripts for SNORA30 Gene

mRNA/cDNA for SNORA30 Gene

(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNA Central transcripts :

Unigene Clusters for SNORA30 Gene

Small nucleolar RNA, H/ACA box 30:
Representative Sequences:

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA30 Gene

No ASD Table

Relevant External Links for SNORA30 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA30 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA30 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA30 Gene:


SOURCE GeneReport for Unigene cluster for SNORA30 Gene:

genes like me logo Genes that share expression patterns with SNORA30: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA30 Gene

Orthologs for SNORA30 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA30 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA30 35
  • 98 (a)
(Canis familiaris)
Mammalia SNORA30 35
  • 89 (a)
(Mus musculus)
Mammalia Snora30 35
  • 85 (a)
(Bos Taurus)
Mammalia SNORA30 35
  • 82 (a)
(Monodelphis domestica)
Mammalia SNORA30 35 35
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA30 35
  • 73 (a)
(Anolis carolinensis)
Reptilia SNORA30 35
  • 53 (a)
(Danio rerio)
Actinopterygii SNORA30 35 35 35 35
  • 54 (a)
Species where no ortholog for SNORA30 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA30 Gene

Gene Tree for SNORA30 (if available)
Gene Tree for SNORA30 (if available)

Paralogs for SNORA30 Gene

No data available for Paralogs for SNORA30 Gene

Variants for SNORA30 Gene

Sequence variations from dbSNP and Humsavar for SNORA30 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs534965827 likely-benign, Floating-Harbor syndrome 30,710,740(+) C/A/T downstream_transcript_variant
rs758394442 uncertain-significance, Floating-Harbor syndrome 30,710,079(+) G/A upstream_transcript_variant
rs774745249 uncertain-significance, Floating-Harbor syndrome 30,710,861(+) G/A downstream_transcript_variant
rs886041787 pathogenic, not provided 30,709,708(+) CCCCC/CCCC upstream_transcript_variant
rs1555463754 uncertain-significance, not specified 30,710,793(+) C/T downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA30 Gene

Variant ID Type Subtype PubMed ID
nsv469724 CNV loss 16826518
nsv833188 CNV loss 17160897

Additional Variant Information for SNORA30 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA30 Gene

Disorders for SNORA30 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNORA30 Gene - From: GeneCards

Disorder Aliases PubMed IDs
floating-harbor syndrome
  • flhs
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SNORA30

genes like me logo Genes that share disorders with SNORA30: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORA30 Gene

Publications for SNORA30 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 1 2 3 58
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 1 2 3 58
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
  5. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) Genome Information Integration Project And H-Invitational 2 … Gojobori T (Nucleic acids research 2008) 1

Products for SNORA30 Gene

Sources for SNORA30 Gene

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