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SNORA21 Gene(RNA Gene)

Small Nucleolar RNA, H/ACA Box 21

GCID:
GC17M038852
GIFtS:
17
Genes Participants
UDN Logo

Aliases for SNORA21 Gene

Subcategory (RNA class) for SNORA21 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORA21 Gene

  • Small Nucleolar RNA, H/ACA Box 21 2 3 5
  • ACA21 Small Nucleolar RNA 3
  • ACA21 SnoRNA 3
  • ACA21 3

External Ids for SNORA21 Gene

ORGUL Members for SNORA21 Gene

Previous GeneCards Identifiers for SNORA21 Gene

  • GC17M034266
  • GC17M037010
  • GC17M032804
  • GC17M037015
  • GC17M037024
  • GC17M037027

Summaries for SNORA21 Gene

GeneCards Summary for SNORA21 Gene

SNORA21 (Small Nucleolar RNA, H/ACA Box 21) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORA21 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA21 Gene

Genomics for SNORA21 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for SNORA21 Gene

Promoters and enhancers for SNORA21 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH17I038850 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 590.6 -0.5 -503 5.2 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC ZC3H11A SNORA21 RPL23 RPS20P35 GC17M038850 GC17M038858 GC17M038862 GC17M038872 GC17M038875 GC17P038858 PIR38457
GH17I038745 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE dbSUPER 65.1 +103.2 103222 8.6 MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 PCGF2 PSMB3 LOC100287808 MED1 CDK12 LOC105371762 SNORA21 RPL23 RPL19 CISD3
GH17I038823 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 69.7 +28.1 28057 3 MLX ZFP64 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC CWC25 MIR4727 MED1 CDK12 SNORA21 LOC105371762 RPL23 STARD3 RPL19 PIP4K2B
GH17I038920 Enhancer 1.2 Ensembl ENCODE dbSUPER 69.7 -69.2 -69230 3.1 ZFP64 SIN3A ZNF213 PAF1 ZNF202 ZNF654 ZBTB11 ZC3H11A REST ZNF623 ENSG00000265784 MED1 CDK12 SNORA21 LOC105371762 RPL23 FBXO47 C17orf98 CWC25 PIP4K2B
GH17I038867 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 31.4 -18.7 -18708 9.2 MLX ZFP64 DMAP1 IRF4 YY1 SLC30A9 ZNF213 ZNF143 ZNF548 SP3 LASP1 MED1 CDK12 SNORA21 LOC105371762 RPL23 CWC25 PSMB3 SNORA21B C17orf98
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORA21 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA21 gene promoter:

Genomic Locations for SNORA21 Gene

Genomic Locations for SNORA21 Gene
chr17:38,852,863-38,852,995
(GRCh38/hg38)
Size:
133 bases
Orientation:
Minus strand
chr17:37,009,116-37,009,248
(GRCh37/hg19)

Genomic View for SNORA21 Gene

Genes around SNORA21 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA21 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA21 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SNORA21 Gene

Proteins for SNORA21 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for SNORA21 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA21 Gene

Domains & Families for SNORA21 Gene

Gene Families for SNORA21 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA21: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA21 Gene

Function for SNORA21 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for SNORA21 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA21 Gene

Localization for SNORA21 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA21 Gene

Pathways & Interactions for SNORA21 Gene

SuperPathways for SNORA21 Gene

PathCards logo More details on SuperPathways for SNORA21
No Data Available

Interacting Proteins for SNORA21 Gene

Gene Ontology (GO) - Biological Process for SNORA21 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA21 Gene

Drugs & Compounds for SNORA21 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for SNORA21 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for SNORA21 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA21 Gene

No ASD Table

Relevant External Links for SNORA21 Gene

GeneLoc Exon Structure for
SNORA21
ECgene alternative splicing isoforms for
SNORA21

Expression for SNORA21 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA21 Gene

mRNA expression in normal human tissues for SNORA21 Gene
mRNA expression by GTEx for SNORA21 GenemRNA expression by BioGPS for SNORA21 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA21 Gene:

SNORA21

SOURCE GeneReport for Unigene cluster for SNORA21 Gene:

Hs.738742
genes like me logo Genes that share expression patterns with SNORA21: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA21 Gene

Orthologs for SNORA21 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA21 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia SNORA21 34
  • 100 (a)
 OneToOne
cow
(Bos Taurus)
 Mammalia SNORA21 34
  • 87 (a)
 OneToOne
dog
(Canis familiaris)
 Mammalia SNORA21 34
  • 86 (a)
 OneToOne
mouse
(Mus musculus)
 Mammalia Snora21 34
  • 85 (a)
 OneToOne
oppossum
(Monodelphis domestica)
 Mammalia SNORA21 34
  • 74 (a)
 OneToOne
platypus
(Ornithorhynchus anatinus)
 Mammalia SNORA21 34
  • 71 (a)
 OneToOne
chicken
(Gallus gallus)
 Aves SNORA21 34
  • 73 (a)
 OneToOne
lizard
(Anolis carolinensis)
 Reptilia SNORA21 34 34
  • 71 (a)
 OneToMany
zebrafish
(Danio rerio)
 Actinopterygii SNORA21 34 34
  • 60 (a)
 OneToMany
Species where no ortholog for SNORA21 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA21 Gene

ENSEMBL:
Gene Tree for SNORA21 (if available)
TreeFam:
Gene Tree for SNORA21 (if available)

Paralogs for SNORA21 Gene

No data available for Paralogs for SNORA21 Gene

Variants for SNORA21 Gene

Sequence variations from dbSNP and Humsavar for SNORA21 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000125424 -- 38,854,507(-) G/C upstream_transcript_variant
rs1000500603 -- 38,854,655(-) G/T upstream_transcript_variant
rs1004881934 -- 38,852,736(-) C/A downstream_transcript_variant
rs1004963868 -- 38,852,461(-) T/C downstream_transcript_variant
rs1005967110 -- 38,853,540(-) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA21 Gene

Variant ID Type Subtype PubMed ID
nsv1146669 OTHER inversion 26484159
nsv833439 CNV loss 17160897

Additional Variant Information for SNORA21 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA21

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA21 Gene

Disorders for SNORA21 Gene

Additional Disease Information for SNORA21

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for SNORA21 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA21 Gene

Publications for SNORA21 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 58
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 58
  3. Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. (PMID: 9047361) Ofengand J … Bakin A (Journal of molecular biology 1997) 2 3 58
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 58
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORA21 Gene

Sources for SNORA21 Gene

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