Small nucleolar RNAs (snoRNAs) are 60-150 nt long non-coding RNAs, and include two groups: C/D box snoRNAs and H/ACA box snoRNAs. The C/D box snoRNAs are guides for the 2'-O-ribose methylation of rRNAs or snRNAs. The H/ACA box snoRNAs are guides for the isomerization of uridine residues into pseudouridine. This gene belongs to the group of the H/ACA box snoRNAs, and functions i... See more...

Aliases for SNORA14B Gene

Subcategory (RNA class) for SNORA14B Gene

snoRNA

Quality Score for this RNA gene is

15

Aliases for SNORA14B Gene

  • Small Nucleolar RNA, H/ACA Box 14B 2 3 5
  • SNORA14B 2 176
  • ACA14b SnoRNA 3
  • RF00397 174
  • ACA14b 3

External Ids for SNORA14B Gene

Previous GeneCards Identifiers for SNORA14B Gene

  • GC01M233357
  • GC01M235291
  • GC01M205739

Summaries for SNORA14B Gene

Entrez Gene Summary for SNORA14B Gene

  • Small nucleolar RNAs (snoRNAs) are 60-150 nt long non-coding RNAs, and include two groups: C/D box snoRNAs and H/ACA box snoRNAs. The C/D box snoRNAs are guides for the 2'-O-ribose methylation of rRNAs or snRNAs. The H/ACA box snoRNAs are guides for the isomerization of uridine residues into pseudouridine. This gene belongs to the group of the H/ACA box snoRNAs, and functions in 18S rRNA pseudouridylation at position U966. The gene duplication generates a 91% identical copy on chromosome 7. [provided by RefSeq, Oct 2008]

GeneCards Summary for SNORA14B Gene

SNORA14B (Small Nucleolar RNA, H/ACA Box 14B) is an RNA Gene, and is affiliated with the snoRNA class.

Rfam classification for SNORA14B Gene

  • Small nucleolar RNA SNORA14

Additional gene information for SNORA14B Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA14B Gene

Genomics for SNORA14B Gene

GeneHancer (GH) Regulatory Elements for SNORA14B Gene

Promoters and enhancers for SNORA14B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNORA14B on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA14B gene promoter:
  • AREB6
  • GATA-1
  • HNF-4alpha1
  • HNF-4alpha2
  • NF-kappaB
  • NF-kappaB1
  • Pax-2
  • Pax-2a
  • Pax-2b
  • YY1

Genomic Locations for SNORA14B Gene

Genomic Locations for SNORA14B Gene
chr1:235,127,803-235,127,937
(GRCh38/hg38)
Size:
135 bases
Orientation:
Minus strand
chr1:235,291,118-235,291,252
(GRCh37/hg19)
Size:
135 bases
Orientation:
Minus strand

Genomic View for SNORA14B Gene

Genes around SNORA14B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA14B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA14B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA14B Gene

Proteins for SNORA14B Gene

Post-translational modifications for SNORA14B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA14B Gene

Domains & Families for SNORA14B Gene

Gene Families for SNORA14B Gene

genes like me logo Genes that share domains with SNORA14B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNORA14B Gene

Function for SNORA14B Gene

Phenotypes From GWAS Catalog for SNORA14B Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA14B Gene

Localization for SNORA14B Gene

Gene Ontology (GO) - Cellular Components for SNORA14B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IEA --
genes like me logo Genes that share ontologies with SNORA14B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SNORA14B Gene

Pathways & Interactions for SNORA14B Gene

PathCards logo

SuperPathways for SNORA14B Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNORA14B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006396 RNA processing IEA --
genes like me logo Genes that share ontologies with SNORA14B: view

No data available for Pathways by source and SIGNOR curated interactions for SNORA14B Gene

Drugs & Compounds for SNORA14B Gene

No Compound Related Data Available

Transcripts for SNORA14B Gene

mRNA/cDNA for SNORA14B Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(1) RNACentral transcripts :
(1) ENA transcripts :
(1) Rfam transcripts :
(1) snOPY transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA14B Gene

No ASD Table

Relevant External Links for SNORA14B Gene

GeneLoc Exon Structure for
SNORA14B
ECgene alternative splicing isoforms for
SNORA14B

Expression for SNORA14B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA14B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA14B Gene:

SNORA14B

SOURCE GeneReport for Unigene cluster for SNORA14B Gene:

Hs.744743
genes like me logo Genes that share expression patterns with SNORA14B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA14B Gene

Orthologs for SNORA14B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA14B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA14 33
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA14 33
  • 79 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA14 33 33
  • 72 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA14 33
  • 62 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA14 33
  • 63 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA14 33 33
  • 52 (a)
ManyToMany
Species where no ortholog for SNORA14B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA14B Gene

ENSEMBL:
Gene Tree for SNORA14B (if available)
TreeFam:
Gene Tree for SNORA14B (if available)

Paralogs for SNORA14B Gene

No data available for Paralogs for SNORA14B Gene

Variants for SNORA14B Gene

Sequence variations from dbSNP and Humsavar for SNORA14B Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000313535 -- 235,129,271(-) A/G upstream_transcript_variant
rs1001820425 -- 235,129,568(-) C/T upstream_transcript_variant
rs1006362798 -- 235,129,836(-) T/C upstream_transcript_variant
rs1008713888 -- 235,129,243(-) G/C upstream_transcript_variant
rs1009315214 -- 235,129,057(-) G/ upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA14B Gene

Variant ID Type Subtype PubMed ID
esv275126 CNV loss 21479260
esv3578486 CNV loss 25503493
esv3891237 CNV loss 25118596
nsv508699 CNV deletion 20534489

Additional Variant Information for SNORA14B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA14B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA14B Gene

Disorders for SNORA14B Gene

Additional Disease Information for SNORA14B

No disorders were found for SNORA14B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA14B Gene

Publications for SNORA14B Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 56
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 56
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 56

Products for SNORA14B Gene

Sources for SNORA14B Gene