Aliases for SNHG8 Gene

Subcategory (RNA class) for SNHG8 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for SNHG8 Gene

  • Small Nucleolar RNA Host Gene 8 2 3 5
  • Small Nucleolar RNA Host Gene 8 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 60 2 3
  • NCRNA00060 2 3
  • LINC00060 2 3
  • SNHG8 5 165
  • Small Nucleolar RNA Host Gene (Non-Protein Coding) 8 3
  • Non-Protein Coding RNA 60 2
  • NONHSAG038728.2 91
  • HSALNG0036656 164

External Ids for SNHG8 Gene

Previous GeneCards Identifiers for SNHG8 Gene

  • GC03P052543
  • GC04U900695
  • GC04P119420
  • GC04P119199
  • GC04P114935

Summaries for SNHG8 Gene

GeneCards Summary for SNHG8 Gene

SNHG8 (Small Nucleolar RNA Host Gene 8) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with SNHG8 include Epstein-Barr Virus-Associated Gastric Carcinoma and Malignant Pleural Mesothelioma.

Rfam classification for SNHG8 Gene

  • Small nucleolar RNA SNORA24

Additional gene information for SNHG8 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNHG8 Gene

Genomics for SNHG8 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SNHG8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J118275 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 657.1 +0.6 575 8.2 RNF2 SP1 HNRNPL CREB1 GATAD2A CTCF PRDM10 ZNF629 REST TFE3 SNHG8 SNORA24 METTL14 CICP16 ENSG00000260404 SEC24D FKBP4P1 RF00017-4397 PRSS12 NDST3
GH04J118352 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas 38.5 +73.5 73492 3.6 HNRNPL CTCF PRDM10 ZNF629 ZNF692 LARP7 ZNF143 ZIC2 ZSCAN4 PATZ1 PRSS12 SNHG8 SNORA24 CICP16 RF00017-4397 NDST3
GH04J118265 Promoter/Enhancer 0.9 ENCODE CraniofacialAtlas 57.7 -13.1 -13141 1 RBFOX2 TFDP1 GABPB1 NFATC3 NFYC ELF1 NRF1 EZH2 LOC105377392 piR-50129-189 SNHG8 METTL14 FKBP4P1 piR-56209 PRSS12 NDST3
GH04J118344 Enhancer 0.6 Ensembl 41 +67.5 67492 3.2 PRDM10 ZSCAN4 POLR2A ZNF561 ZBTB44 NFE2 OSR2 ZBTB17 ZNF189 ZNF213 SNHG8 CICP16 FKBP4P1 PRSS12 RF00017-4397 NDST3
GH04J118285 Enhancer 0.7 Ensembl ENCODE 28.5 +10.0 10048 5.8 CEBPB FOS MAFK JUND HNF4A ATF2 NFE2L2 POLR2A SNHG8 PRSS12 CICP16 SNORA24 RF00017-4397 NDST3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SNHG8 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SNHG8 gene promoter:
  • AREB6
  • C/EBPalpha
  • HOXA5
  • HOXA9
  • Meis-1
  • Meis-1b
  • MyoD
  • NF-1
  • POU2F1
  • POU2F1a

Genomic Locations for SNHG8 Gene

Genomic Locations for SNHG8 Gene
chr4:118,278,709-118,285,316
(GRCh38/hg38)
Size:
6,608 bases
Orientation:
Plus strand
chr4:119,199,864-119,200,978
(GRCh37/hg19)
Size:
1,115 bases
Orientation:
Plus strand

Genomic View for SNHG8 Gene

Genes around SNHG8 on UCSC Golden Path with GeneCards custom track
SNHG8 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
SNHG8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNHG8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNHG8 Gene

Proteins for SNHG8 Gene

Post-translational modifications for SNHG8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNHG8 Gene

Domains & Families for SNHG8 Gene

Gene Families for SNHG8 Gene

genes like me logo Genes that share domains with SNHG8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNHG8 Gene

Function for SNHG8 Gene

Phenotypes From GWAS Catalog for SNHG8 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNHG8 Gene

Localization for SNHG8 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNHG8 gene
Compartment Confidence
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNHG8 Gene

Pathways & Interactions for SNHG8 Gene

PathCards logo

SuperPathways for SNHG8 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SNHG8 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SNHG8 Gene

Drugs & Compounds for SNHG8 Gene

No Compound Related Data Available

Transcripts for SNHG8 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNHG8 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00002E836D_9606 lncRNA 570 3

Ensembl: ENST00000602573 (view in UCSC) ,

LncBook: HSALNT0076744,

LNCipedia: SNHG8:14,

URS000044661E_9606 lncRNA 327 3

Ensembl: ENST00000602520 (view in UCSC) ,

LNCipedia: SNHG8:1,

NONCODE: NONHSAT097972.2,

URS000021FE83_9606 lncRNA 309 3

Ensembl: ENST00000602483 (view in UCSC) ,

LNCipedia: SNHG8:4,

NONCODE: NONHSAT097974.2,

URS0000EF634E_9606 lncRNA 6165 1

Ensembl: ENST00000654083 (view in UCSC) ,

URS0000EEF593_9606 lncRNA 1105 1

Ensembl: ENST00000667980 (view in UCSC) ,

SNHG8 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for SNHG8 Gene

5 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNHG8 Gene

No ASD Table

Relevant External Links for SNHG8 Gene

GeneLoc Exon Structure for
SNHG8

Expression for SNHG8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNHG8 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNHG8

SOURCE GeneReport for Unigene cluster for SNHG8 Gene:

Hs.535762
genes like me logo Genes that share expression patterns with SNHG8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNHG8 Gene

Orthologs for SNHG8 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNHG8 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SNORA24 31
  • 100 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia SNORA24 31
  • 98 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia SNORA24 31
  • 91 (a)
OneToMany
Cow
(Bos Taurus)
Mammalia SNORA24 31
  • 87 (a)
ManyToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia SNORA24 31 31 31 31
  • 82 (a)
ManyToMany
Mouse
(Mus musculus)
Mammalia Gm24918 31
  • 79 (a)
OneToOne
Chicken
(Gallus gallus)
Aves SNORA24 31
  • 73 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia SNORA24 31
  • 69 (a)
OneToMany
Species where no ortholog for SNHG8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for SNHG8 Gene

ENSEMBL:
Gene Tree for SNHG8 (if available)
TreeFam:
Gene Tree for SNHG8 (if available)

Paralogs for SNHG8 Gene

No data available for Paralogs for SNHG8 Gene

Variants for SNHG8 Gene

Additional dbSNP identifiers (rs#s) for SNHG8 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNHG8 Gene

Variant ID Type Subtype PubMed ID
dgv5372n100 CNV loss 25217958
esv2759279 CNV gain 17122850
esv34038 CNV loss 18971310
esv34354 CNV gain 17911159
esv3894015 CNV gain 25118596
nsv1002771 CNV gain 25217958
nsv519017 CNV loss 19592680

Additional Variant Information for SNHG8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNHG8

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SNHG8 Gene

Disorders for SNHG8 Gene

MalaCards: The human disease database

(4) MalaCards diseases for SNHG8 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
epstein-barr virus-associated gastric carcinoma
  • ebv-associated gastric carcinoma
malignant pleural mesothelioma
  • malignant mesothelioma of pleura
neuroblastoma
  • nb
gastric cancer
  • gastric cancer, somatic
- elite association - COSMIC cancer census association via MalaCards
Search SNHG8 in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with SNHG8: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNHG8 Gene

Publications for SNHG8 Gene

  1. SNHG8 is identified as a key regulator of epstein-barr virus(EBV)-associated gastric cancer by an integrative analysis of lncRNA and mRNA expression. (PMID: 27835598) Huang T … Lin X (Oncotarget 2016) 2 3
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3
  3. Knockdown of SNHG8 repressed the growth, migration, and invasion of colorectal cancer cells by directly sponging with miR-663. (PMID: 31152930) Zhen Y … Deng X (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019) 3
  4. LncRNA SNHG8 is identified as a key regulator of acute myocardial infarction by RNA-seq analysis. (PMID: 31739782) Zhuo LA … Miao L (Lipids in health and disease 2019) 3
  5. lncRNA SNHG8 Promotes the Tumorigenesis and Metastasis by Sponging miR-149-5p and Predicts Tumor Recurrence in Hepatocellular Carcinoma. (PMID: 30537734) Dong J … Fu Z (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018) 3

Products for SNHG8 Gene

Sources for SNHG8 Gene