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This locus represents a small nucleolar RNA host gene that produces multiple alternatively spliced long non-coding RNAs. This gene is upregulated in cancers and is thought to act as promoter of cell proliferation. This transcript negatively regulates tumor suppressor genes such as tumor protein p53. Expression of this locus may be a marker of tumor progression. [provided by RefSeq, Dec 2017]
SNHG1 (Small Nucleolar RNA Host Gene 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with SNHG1 include Lung Squamous Cell Carcinoma and Neuroblastoma.
GO ID | Qualified GO term | Evidence | PubMed IDs |
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GO:0005730 | nucleolus | IEA | -- |
RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
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URS00008C22F5_9606 | lncRNA | 1487 | 4 |
Ensembl: ENST00000537925 (view in UCSC) , LncBook: HSALNT0176342, LNCipedia: SNHG1:10, NONCODE: NONHSAT021828.2, |
URS00008C409D_9606 | lncRNA | 1038 | 4 |
Ensembl: ENST00000537869 (view in UCSC) , LncBook: HSALNT0176357, LNCipedia: SNHG1:27, NONCODE: NONHSAT021831.2, |
URS00008C3AA7_9606 | lncRNA | 955 | 4 |
Ensembl: ENST00000539975 (view in UCSC) , LncBook: HSALNT0176360, LNCipedia: SNHG1:29, NONCODE: NONHSAT021832.2, |
URS00008C0CC6_9606 | lncRNA | 754 | 4 |
Ensembl: ENST00000545440 (view in UCSC) , LncBook: HSALNT0176364, HSALNT0288955, LNCipedia: SNHG1:18, NONCODE: NONHSAT021834.2, |
URS00008C2147_9606 | lncRNA | 638 | 4 |
Ensembl: ENST00000537068 (view in UCSC) , LncBook: HSALNT0176341, LNCipedia: SNHG1:5, NONCODE: NONHSAT021824.2, |
Disorder | Aliases | PubMed IDs |
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lung squamous cell carcinoma |
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neuroblastoma |
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multiple pterygium syndrome, escobar variant |
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esophageal cancer |
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parkinson disease, late-onset |
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