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SNED1 (Sushi, Nidogen And EGF Like Domains 1) is a Protein Coding gene. Diseases associated with SNED1 include Cortical Thymoma and Hyperpituitarism. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is NOTCH1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005112 | Notch binding | IBA | 21873635 |
GO:0005509 | calcium ion binding | IEA | -- |
GO:0005515 | protein binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007160 | cell-matrix adhesion | IEA | -- |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19 | ^ | 20 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||
SP4: | |||||||||||||||||||||||||||||||||||||||||||||
SP5: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SNED1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | SNED1 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Sned1 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Sned1 30 17 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | SNED1 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | SNED1 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | SNED1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | SNED1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | SNED1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | sned1 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | sned1 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | C901 31 |
|
ManyToMany | |
uif 31 |
|
ManyToMany | |||
Worm (Caenorhabditis elegans) |
Secernentea | lin-12 31 |
|
ManyToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany |
SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs139139954 | Benign: not provided | 241,037,292(+) |
C/T NM_001080437.3(SNED1):c.984C>T (p.His328=) |
SYNONYMOUS | |
rs1553548453 | Not Provided: not provided | 240,999,044(+) |
A/ACT NM_001080437.3(SNED1):c.208_209CT[3] (p.Tyr71fs) |
FRAMESHIFT | |
rs186778143 | Benign: not provided | 241,070,110(+) |
G/A NM_001080437.3(SNED1):c.3498G>A (p.Pro1166=) |
SYNONYMOUS | |
rs376157092 | Likely Benign: not provided | 241,082,272(+) |
C/T NM_001080437.3(SNED1):c.4034-5C>T |
INTRON | |
rs59269476 | Benign: not provided | 241,040,361(+) |
G/T NM_001080437.3(SNED1):c.1221G>T (p.Gly407=) |
SYNONYMOUS |
Disorder | Aliases | PubMed IDs |
---|---|---|
cortical thymoma |
|
|
hyperpituitarism |
|
|
growth hormone secreting pituitary adenoma |
|
|
meningioma, familial |
|
|