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Aliases for SNCA-AS1 Gene
Subcategory (RNA class) for SNCA-AS1 Gene
lncRNA
Aliases for SNCA-AS1 Gene
External Ids for SNCA-AS1 Gene
- HGNC: 50600
- NCBI Entrez Gene: 644248
- Ensembl: ENSG00000247775
Summaries for SNCA-AS1 Gene
GeneCards Summary for SNCA-AS1 Gene
SNCA-AS1 (SNCA Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class.
Additional gene information for SNCA-AS1 Gene
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SNCA-AS1 Gene
Genomics for SNCA-AS1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SNCA-AS1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH04J089837 | Promoter/Enhancer | 1.8 | EPDnew Ensembl ENCODE CraniofacialAtlas | 250.7 | +0.6 | 601 | 3.6 | ZSCAN16 ZNF610 ZNF513 CTCF ZNF341 ZNF843 KLF9 SP2 TAL1 KLF16 | SNCA SNCA-AS1 GPRIN3 | |
| GH04J089799 | Enhancer | 0.6 | Ensembl ENCODE | 6.2 | -35.8 | -35799 | 4 | JUND ZNF366 EP300 | MMRN1 SNCA-AS1 SNCA piR-50852-111 lnc-MMRN1-3 GPRIN3 | |
| GH04J089829 | Enhancer | 0.6 | ENCODE | 0.4 | -6.5 | -6536 | 0.8 | SPI1 ELF1 IKZF1 ATF7 RAD51 IKZF2 MTA2 DPF2 RELB ETV6 | SNCA SNCA-AS1 piR-50852-111 GPRIN3 | |
| GH04J089819 | Enhancer | 0.5 | Ensembl | 0.4 | -15.8 | -15799 | 2.8 | SPI1 ATF2 ZNF366 ZNF512 ATF7 PRDM1 | SNCA MMRN1 SNCA-AS1 piR-50852-111 GPRIN3 | |
| GH04J089797 | Enhancer | 0.5 | Ensembl ENCODE | 0.3 | -38.9 | -38900 | 0.6 | JUND EP300 | piR-50852-111 lnc-MMRN1-3 SNCA-AS1 SNCA GPRIN3 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SNCA-AS1 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for SNCA-AS1 Gene
Latest Assembly
- chr4:89,836,400-89,842,300
- (GRCh38/hg38)
- Size:
- 5,901 bases
- Orientation:
- Plus strand
Previous Assembly
- chr4:90,757,552-90,763,142
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 5,591 bases
- Orientation:
- Plus strand
- chr4:90,757,559-90,763,129
- (GRCh37/hg19 by Ensembl)
- Size:
- 5,571 bases
- Orientation:
- Plus strand
Genomic View for SNCA-AS1 Gene
Genes around SNCA-AS1 on UCSC Golden Path with GeneCards custom track
SNCA-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
- Cytogenetic band:
-
- 4q22.1 by HGNC
- 4q22.1 by Entrez Gene
- 4q22.1 by Ensembl
SNCA-AS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SNCA-AS1 Gene
Proteins for SNCA-AS1 Gene
Post-translational modifications for SNCA-AS1 Gene
No Post-translational modifications
No data available for DME Specific Peptides for SNCA-AS1 Gene
Domains & Families for SNCA-AS1 Gene
Gene Families for SNCA-AS1 Gene
- HGNC:
No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SNCA-AS1 Gene
Function for SNCA-AS1 Gene
Phenotypes From GWAS Catalog for SNCA-AS1 Gene
CRISPR products for research
Inhibitory RNAs for research
Clone products for research
Cell Lines for research
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNCA-AS1 Gene
Localization for SNCA-AS1 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNCA-AS1 Gene
Transcripts for SNCA-AS1 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for SNCA-AS1 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS000041475A_9606 | lncRNA | 2646 | 3 |
Ensembl: ENST00000501215 (view in UCSC) , LNCipedia: SNCA-AS1:3, NONCODE: NONHSAT097404.2, |
| URS000075B38D_9606 | lncRNA | 825 | 3 |
RefSeq: NR_045481, LNCipedia: SNCA-AS1:1, NONCODE: NONHSAT097403.2, |
| URS000046C31B_9606 | lncRNA | 801 | 2 |
Ensembl: ENST00000513653 (view in UCSC) , LNCipedia: SNCA-AS1:2, |
| URS0001BDF63E_9606 | lncRNA | 4435 | 1 |
LncBook: HSALNT0074994, |
| URS0001BF77E5_9606 | lncRNA | 3060 | 1 |
LncBook: HSALNT0074995, |
SNCA-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for SNCA-AS1 Gene
- 8 NCBI additional mRNA sequence :
CRISPR products for research
Inhibitory RNAs for research
Clone products for research
Relevant External Links for SNCA-AS1 Gene
- GeneLoc Exon Structure for
- SNCA-AS1
Expression for SNCA-AS1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SNCA-AS1
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNCA-AS1 Gene
Orthologs for SNCA-AS1 Gene
No data available for Orthologs for SNCA-AS1 Gene
Paralogs for SNCA-AS1 Gene
No data available for Paralogs for SNCA-AS1 Gene
Variants for SNCA-AS1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SNCA-AS1 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 904211 | Uncertain Significance: Parkinson Disease, Dominant | 89,836,955(+) |
C/T NM_000345.4(SNCA):c.-26+7G>A |
NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR_VARIANT,INTRON | |
| 904212 | Uncertain Significance: Parkinson Disease, Dominant | 89,837,051(+) |
G/C NM_000345.4(SNCA):c.-115C>G |
NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR_VARIANT,INTRON | |
| 904994 | Uncertain Significance: Parkinson Disease, Dominant | 89,837,063(+) |
G/A NM_000345.4(SNCA):c.-127C>T |
NON_CODING_TRANSCRIPT_VARIANT,FIVE_PRIME_UTR_VARIANT,INTRON | |
| rs1560562993 | Uncertain Significance: Parkinson Disease, Dominant | 89,836,961(+) |
C/T NM_000345.4(SNCA):c.-26+1G>A |
SPLICE_DONOR_VARIANT,FIVE_PRIME_UTR_VARIANT,INTRON | |
| rs367902113 | Uncertain Significance: Parkinson Disease, Dominant | 89,837,065(+) |
C/T NM_000345.4(SNCA):c.-129G>A |
FIVE_PRIME_UTR_VARIANT,INTRON |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Additional Variant Information for SNCA-AS1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SNCA-AS1
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNCA-AS1 Gene
Disorders for SNCA-AS1 Gene
Additional Disease Information for SNCA-AS1
No disorders were found for SNCA-AS1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNCA-AS1 Gene
Publications for SNCA-AS1 Gene
- Creation of genome-wide protein expression libraries using random activation of gene expression. (PMID: 11329013) Harrington JJ … Ducar M (Nature biotechnology 2001) 3
ExternalLinks
Products for SNCA-AS1 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SNCA-AS1
- Origene Custom Protein Services for SNCA-AS1
- Browse OriGene Inhibitory RNA Products For SNCA-AS1
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for SNCA-AS1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SNCA-AS1
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for knockout CRISPR/Cas9 clones, lentivirus, and/or AAV products for SNCA-AS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles, and/or promoter clone products for SNCA-AS1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SNCA-AS1
- Search GeneCopoeia for shRNA, lentivirus, and/or AAV clone products for SNCA-AS1
Sources for SNCA-AS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB