Aliases for SNAI3 Gene
External Ids for SNAI3 Gene
Previous HGNC Symbols for SNAI3 Gene
Previous GeneCards Identifiers for SNAI3 Gene
SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).[supplied by OMIM, Apr 2009]
GeneCards Summary for SNAI3 Gene
SNAI3 (Snail Family Transcriptional Repressor 3) is a Protein Coding gene. Diseases associated with SNAI3 include Parkinson Disease 7, Autosomal Recessive Early-Onset. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and copper ion binding. An important paralog of this gene is SNAI2.
UniProtKB/Swiss-Prot Summary for SNAI3 Gene
Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3' (By similarity).