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SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).[supplied by OMIM, Apr 2009]
SNAI3 (Snail Family Transcriptional Repressor 3) is a Protein Coding gene. Diseases associated with SNAI3 include Parkinson Disease 7, Autosomal Recessive Early-Onset. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and copper ion binding. An important paralog of this gene is SNAI2.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | IEA | -- |
GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA | -- |
GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | IEA | -- |
GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | IEA | -- |
GO:0003676 | nucleic acid binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IBA | 21873635 |
GO:0005667 | transcription factor complex | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000122 | negative regulation of transcription by RNA polymerase II | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA,IBA | 21873635 |
GO:0006357 | regulation of transcription by RNA polymerase II | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SNAI3 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | SNAI3 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | SNAI3 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Snai3 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Snai3 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | SNAI3 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | SNAI3 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | SNAI3 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | snai3 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | snai3 30 31 |
|
OneToOne | |
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.6891 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | sna 31 |
|
ManyToMany | |
esg 31 |
|
ManyToMany | |||
wor 31 |
|
ManyToMany | |||
Worm (Caenorhabditis elegans) |
Secernentea | K02D7.2 31 |
|
ManyToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8617 31 |
|
OneToMany | |
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.15314 30 |
|
Disorder | Aliases | PubMed IDs |
---|---|---|
parkinson disease 7, autosomal recessive early-onset |
|
|