Aliases for SMYD1 Gene
External Ids for SMYD1 Gene
Previous GeneCards Identifiers for SMYD1 Gene
GeneCards Summary for SMYD1 Gene
SMYD1 (SET And MYND Domain Containing 1) is a Protein Coding gene. Diseases associated with SMYD1 include Hypertrophic Cardiomyopathy. Among its related pathways are Lysine degradation and Heart Development. Gene Ontology (GO) annotations related to this gene include transcription corepressor activity and histone-lysine N-methyltransferase activity. An important paralog of this gene is SMYD2.
UniProtKB/Swiss-Prot Summary for SMYD1 Gene
Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.