Aliases for SMPDL3B Gene
External Ids for SMPDL3B Gene
Previous GeneCards Identifiers for SMPDL3B Gene
GeneCards Summary for SMPDL3B Gene
SMPDL3B (Sphingomyelin Phosphodiesterase Acid Like 3B) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include hydrolase activity and sphingomyelin phosphodiesterase activity. An important paralog of this gene is SMPDL3A.
UniProtKB/Swiss-Prot for SMPDL3B Gene
Lipid-modulating phosphodiesterase (PubMed:26095358). Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (By similarity).