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Aliases for SMKR1 Gene

Aliases for SMKR1 Gene

  • Small Lysine Rich Protein 1 2 3 5

External Ids for SMKR1 Gene

Previous GeneCards Identifiers for SMKR1 Gene

  • GC07P129145

Summaries for SMKR1 Gene

GeneCards Summary for SMKR1 Gene

SMKR1 (Small Lysine Rich Protein 1) is a Protein Coding gene.

Additional gene information for SMKR1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMKR1 Gene

Genomics for SMKR1 Gene

GeneHancer (GH) Regulatory Elements for SMKR1 Gene

Promoters and enhancers for SMKR1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I129501 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 563 +0.1 114 1.6 SIN3A ZNF2 GLIS2 ZNF143 ZNF202 SP3 SREBF1 ZNF610 RFX3 MYNN SMKR1 ENSG00000242588 NRF1 RPS10P15 PIR51011
GH07I129438 Enhancer 1.4 Ensembl ENCODE dbSUPER 9.3 -63.3 -63317 2.1 HDGF HNRNPUL1 PKNOX1 FOXA2 ARNT ZNF766 E2F8 FOS REST ZNF592 GC07P129440 ENSG00000230715 ENSG00000243302 ENSG00000242588 ENSG00000243679 TNPO3 ENSG00000229413 RPS10P15 RNU7-16P CDC26P1
GH07I129776 Enhancer 1.5 FANTOM5 Ensembl ENCODE 5.1 +277.0 277007 6.4 HDGF CLOCK ARID4B SIN3A ZNF2 ZBTB7B POLR2B ZNF213 FOS SP3 TNPO3 KLHDC10 UBE2H ENSG00000273329 SMKR1 FLNC STRIP2 GC07M129785 MIR183
GH07I129493 Enhancer 0.8 Ensembl ENCODE 9.3 -8.5 -8523 1.5 CTCF RFX1 NR4A1 JUNB CEBPG ATF7 FOS PRDM10 RUNX3 AHCYL2 ENSG00000243230 SMKR1 RNU1-72P
GH07I129488 Enhancer 0.7 ENCODE 9.4 -12.9 -12854 1.5 ZNF639 ZNF740 CAVIN1 NR4A1 E2F5 PYGO2 HDAC8 ZNF395 RELA ZNF592 AHCYL2 ENSG00000243230 SMKR1 STRIP2 RNU1-72P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SMKR1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SMKR1 Gene

Genomic Locations for SMKR1 Gene
chr7:129,502,479-129,512,932
(GRCh38/hg38)
Size:
10,454 bases
Orientation:
Plus strand
chr7:129,142,320-129,152,773
(GRCh37/hg19)

Genomic View for SMKR1 Gene

Genes around SMKR1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMKR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMKR1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMKR1 Gene

Proteins for SMKR1 Gene

  • Protein details for SMKR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H3BMG3-SMKR1_HUMAN
    Recommended name:
    Small lysine-rich protein 1
    Protein Accession:
    H3BMG3

    Protein attributes for SMKR1 Gene

    Size:
    65 amino acids
    Molecular mass:
    7091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SMKR1 Gene

Post-translational modifications for SMKR1 Gene

No Post-translational modifications

Other Protein References for SMKR1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMKR1 Gene

Domains & Families for SMKR1 Gene

Gene Families for SMKR1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for SMKR1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMKR1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMKR1 Gene

Function for SMKR1 Gene

Phenotypes From GWAS Catalog for SMKR1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SMKR1 Gene

Localization for SMKR1 Gene

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SMKR1 Gene

Pathways & Interactions for SMKR1 Gene

SuperPathways for SMKR1 Gene

No Data Available

Interacting Proteins for SMKR1 Gene

Gene Ontology (GO) - Biological Process for SMKR1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SMKR1 Gene

Drugs & Compounds for SMKR1 Gene

No Compound Related Data Available

Transcripts for SMKR1 Gene

mRNA/cDNA for SMKR1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMKR1 Gene

Small lysine-rich protein 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMKR1 Gene

No ASD Table

Relevant External Links for SMKR1 Gene

GeneLoc Exon Structure for
SMKR1
ECgene alternative splicing isoforms for
SMKR1

Expression for SMKR1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SMKR1 Gene

mRNA differential expression in normal tissues according to GTEx for SMKR1 Gene

This gene is overexpressed in Testis (x30.4).

NURSA nuclear receptor signaling pathways regulating expression of SMKR1 Gene:

SMKR1

SOURCE GeneReport for Unigene cluster for SMKR1 Gene:

Hs.178144
genes like me logo Genes that share expression patterns with SMKR1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMKR1 Gene

Orthologs for SMKR1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SMKR1 Gene

Organism Taxonomy Gene Similarity Type Details
platypus
(Ornithorhynchus anatinus)
Mammalia SMKR1 34
  • 46 (a)
OneToOne
Species where no ortholog for SMKR1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SMKR1 Gene

ENSEMBL:
Gene Tree for SMKR1 (if available)
TreeFam:
Gene Tree for SMKR1 (if available)

Paralogs for SMKR1 Gene

No data available for Paralogs for SMKR1 Gene

Variants for SMKR1 Gene

Sequence variations from dbSNP and Humsavar for SMKR1 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000405462 -- 129,505,448(+) T/C intron_variant
rs1000775528 -- 129,502,523(+) C/G 5_prime_UTR_variant
rs1000937181 -- 129,505,069(+) T/C intron_variant
rs1000999133 -- 129,512,288(+) T/C coding_sequence_variant, synonymous_variant
rs1001439228 -- 129,505,337(+) C/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for SMKR1 Gene

Variant ID Type Subtype PubMed ID
esv2656736 CNV deletion 23128226
esv3614999 CNV loss 21293372
nsv831128 CNV gain 17160897

Variation tolerance for SMKR1 Gene

Gene Damage Index Score: 2.15; 39.08% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SMKR1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMKR1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMKR1 Gene

Disorders for SMKR1 Gene

Additional Disease Information for SMKR1

No disorders were found for SMKR1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMKR1 Gene

Publications for SMKR1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  2. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 4 58

Products for SMKR1 Gene

Sources for SMKR1 Gene

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