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Aliases for SMIM5 Gene
Aliases for SMIM5 Gene
External Ids for SMIM5 Gene
- HGNC: 40030
- Entrez Gene: 643008
- Ensembl: ENSG00000204323
- UniProtKB: Q71RC9
Previous HGNC Symbols for SMIM5 Gene
- C17orf109
Previous GeneCards Identifiers for SMIM5 Gene
- GC17P073632
Summaries for SMIM5 Gene
GeneCards Summary for SMIM5 Gene
SMIM5 (Small Integral Membrane Protein 5) is a Protein Coding gene.
No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SMIM5 Gene
Genomics for SMIM5 Gene
GeneHancer (GH) Regulatory Elements for SMIM5 Gene
Promoters and enhancers for SMIM5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SMIM5 on UCSC Golden Path with GeneCards custom track
Genomic Locations for SMIM5 Gene
Genomic Locations for SMIM5 Gene
- chr17:75,633,434-75,641,406
- (GRCh38/hg38)
- Size:
- 7,973 bases
- Orientation:
- Plus strand
- chr17:73,629,514-73,637,486
- (GRCh37/hg19)
- Size:
- 7,973 bases
- Orientation:
- Plus strand
Genomic View for SMIM5 Gene
Genes around SMIM5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by HGNC
- 17q25.1 by Entrez Gene
- 17q25.1 by Ensembl
SMIM5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SMIM5 Gene
Proteins for SMIM5 Gene
-
Protein details for SMIM5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q71RC9-SMIM5_HUMAN
- Recommended name:
- Small integral membrane protein 5
- Protein Accession:
- Q71RC9
Protein attributes for SMIM5 Gene
- Size:
- 77 amino acids
- Molecular mass:
- 8540 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAQ15244.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=EAW89296.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for SMIM5 Gene
Post-translational modifications for SMIM5 Gene
No Post-translational modifications
Other Protein References for SMIM5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-SMIM5 Antibody (HPA071268) and Anti-SMIM5 Antibody (HPA065332)
- Novus Biologicals Antibodies for SMIM5
- Invitrogen Antibodies for SMIM5 (AFLGC-SMIM5)
Protein Products
- Atlas Antibodies PrEST Antigen SMIM5 (APrEST88688) and PrEST Antigen SMIM5 (APrEST92558)
- Creative Biomart Recombinant Human SMIM5 and Recombinant Human SMIM5 Protein, MYC/DDK-tagged
-
OriGene Purified Proteins for SMIM5
- Search Origene for MassSpec and Protein Over-expression Lysates for SMIM5
- Origene Custom Protein Services for SMIM5
- Novus Biologicals proteins for SMIM5
No data available for DME Specific Peptides for SMIM5 Gene
Domains & Families for SMIM5 Gene
Gene Families for SMIM5 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SMIM5 Gene
Function for SMIM5 Gene
Phenotypes From GWAS Catalog for SMIM5 Gene
Phenotypes for SMIM5 Gene
- GenomeRNAi human phenotypes for SMIM5:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for SMIM5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SMIM5
- genomics-online: gRNA clones - Search results for available SMIM5 gene related products
- Applied Biological Materials (abm): CRISPR Clones for SMIM5 - Select products 50% OFF >
- * SMIM5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SMIM5 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for SMIM5
miRNA Products
Inhibitory RNA Products
- Origene sirna and RNAi products in human, mouse, rat for SMIM5
- Browse OriGene Inhibitory RNA Products For SMIM5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMIM5
- genomics-online: shRNA clones - Search results for available SMIM5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for SMIM5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SMIM5
- genomics-online: cdna clones - Search results for available SMIM5 gene related products
- orf clones - Search results for available SMIM5 gene related products
- Applied Biological Materials (abm): Clones for SMIM5 - Select products 50% OFF >
- * SMIM5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SMIM5 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for SMIM5
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMIM5 Gene
Localization for SMIM5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SMIM5 Gene
- Membrane; Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| nucleus | 1 |
| cytosol | 1 |
| extracellular | 0 |
- Golgi apparatus (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for SMIM5 Gene
Interacting Proteins for SMIM5 Gene
Selected Interacting proteins:
Q71RC9-SMIM5_HUMAN
ENSP00000477017
for SMIM5 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SMIM5
No data available for Pathways by source and SIGNOR curated interactions for SMIM5 Gene
Drugs & Compounds for SMIM5 Gene
No Compound Related Data Available
Drug Products
- Atlas Antibodies PrEST Antigen SMIM5 (APrEST88688) and PrEST Antigen SMIM5 (APrEST92558)
- Creative Biomart Recombinant Human SMIM5 and Recombinant Human SMIM5 Protein, MYC/DDK-tagged
Transcripts for SMIM5 Gene
mRNA/cDNA for SMIM5 Gene
- (1) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000375215 1546 bps (ENST00000375215.3)
- ENST00000537494 4344 bps (ENST00000537494.1)
- ENST00000581115 662 bps (ENST00000581115.1)
CRISPR Products
-
OriGene CRISPR knockouts for SMIM5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SMIM5
- genomics-online: gRNA clones - Search results for available SMIM5 gene related products
- Applied Biological Materials (abm): CRISPR Clones for SMIM5 - Select products 50% OFF >
- * SMIM5 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SMIM5 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for SMIM5
miRNA Products
Inhibitory RNA Products
- Origene sirna and RNAi products in human, mouse, rat for SMIM5
- Browse OriGene Inhibitory RNA Products For SMIM5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMIM5
- genomics-online: shRNA clones - Search results for available SMIM5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for SMIM5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SMIM5
- genomics-online: cdna clones - Search results for available SMIM5 gene related products
- orf clones - Search results for available SMIM5 gene related products
- Applied Biological Materials (abm): Clones for SMIM5 - Select products 50% OFF >
- * SMIM5 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SMIM5 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Expression for SMIM5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- Glycinergic Amacrine Cells Inner Nuclear Layer
-
Ovary (Reproductive System)
- Pre-Granulosa Cells Primordial Follicle
- Bone (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for SMIM5 Gene
This gene is overexpressed in Esophagus - Mucosa (x4.8).
This gene is overexpressed in Platelet (27.8), Urine (20.5), and Bone (18.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SMIM5 Gene
NURSA nuclear receptor signaling pathways regulating expression of SMIM5 Gene:
SMIM5SOURCE GeneReport for Unigene cluster for SMIM5 Gene:
Hs.528605Primer Products
- genomics-online: primer clones - Search results for available SMIM5 gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMIM5 Gene
Orthologs for SMIM5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | C17H17orf109 32 |
|
||
| SMIM5 33 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | SMIM5 32 |
|
||
| mouse (Mus musculus) |
Mammalia | Smim5 17 33 32 |
|
||
| cow (Bos Taurus) |
Mammalia | SMIM5 33 32 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | SMIM5 33 |
|
OneToOne |
- Species where no ortholog for SMIM5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for SMIM5 Gene
- ENSEMBL:
- Gene Tree for SMIM5 (if available)
- TreeFam:
- Gene Tree for SMIM5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SMIM5: view image
Paralogs for SMIM5 Gene
No data available for Paralogs for SMIM5 Gene
Variants for SMIM5 Gene
| SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000045499 | -- | 75,632,266(+) | G/A | upstream_transcript_variant | |
| rs1000059605 | -- | 75,635,014(+) | C/T | 3_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000333509 | -- | 75,640,066(+) | T/C | 5_prime_UTR_variant, genic_downstream_transcript_variant, intron_variant, non_coding_transcript_variant | |
| rs1000872473 | -- | 75,638,650(+) | GGGGGGG/GGGGGGGG | genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant, non_coding_transcript_variant, upstream_transcript_variant | |
| rs1001378645 | -- | 75,639,686(+) | G/A | 5_prime_UTR_variant, genic_downstream_transcript_variant, intron_variant, non_coding_transcript_variant |
Gene Damage Index Score:
1.01;
20.72% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SMIM5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SMIM5
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMIM5 Gene
Disorders for SMIM5 Gene
Additional Disease Information for SMIM5
No disorders were found for SMIM5 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM5 Gene
Publications for SMIM5 Gene
- FUT11 as a potential biomarker of clear cell renal cell carcinoma progression based on meta-analysis of gene expression data. (PMID: 24318988) Zodro E … Wesoly J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014) 2 3 56
- A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. (PMID: 28065597) Yao Z … Stagljar I (Molecular cell 2017) 3 56
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 56
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 56
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 56
ExternalLinks
Products for SMIM5 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for SMIM5
- Search Origene for MassSpec and Protein Over-expression Lysates for SMIM5
- Origene Custom Protein Services for SMIM5
- Origene sirna and RNAi products in human, mouse, rat for SMIM5
- Browse OriGene Inhibitory RNA Products For SMIM5
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for SMIM5
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SMIM5
- Sino Biological Human cDNA Clone for SMIM5
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for SMIM5
- Novus Biologicals proteins for SMIM5
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for SMIM5 (AFLGC-SMIM5)
- antibodies-online: Search results for available SMIM5 related products ranked by validation data
- antibodies-online: Search results for available SMIM5 related products ranked by validation data
- antibodies-online: Search results for available SMIM5 related products ranked by validation data
- Horizon Cell Lines for SMIM5
- genomics-online: cdna clones - Search results for available SMIM5 gene related products
- orf clones - Search results for available SMIM5 gene related products
- genomics-online: gRNA clones - Search results for available SMIM5 gene related products
- genomics-online: primer clones - Search results for available SMIM5 gene related products
- genomics-online: shRNA clones - Search results for available SMIM5 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SMIM5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SMIM5
- Search GeneCopoeia for miRNA 3'UTR Target clone products for SMIM5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMIM5
Sources for SMIM5 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource