Aliases for SMIM35 Gene

Aliases for SMIM35 Gene

  • Small Integral Membrane Protein 35 2 3 4 5
  • TMPRSS4 Antisense RNA 1 (Non-Protein Coding) 2 3
  • TMPRSS4 Antisense RNA 1 2 4
  • TMPRSS4-AS1 3 4
  • SMIM35 5

External Ids for SMIM35 Gene

Previous HGNC Symbols for SMIM35 Gene

  • TMPRSS4-AS1

Summaries for SMIM35 Gene

GeneCards Summary for SMIM35 Gene

SMIM35 (Small Integral Membrane Protein 35) is a Protein Coding gene. Diseases associated with SMIM35 include Inflammatory Bowel Disease 28, Autosomal Recessive and Inflammatory Bowel Disease 28.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SMIM35 Gene

Genomics for SMIM35 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SMIM35 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SMIM35 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SMIM35

Genomic Locations for SMIM35 Gene

Latest Assembly
chr11:118,000,027-118,089,911
(GRCh38/hg38)
Size:
89,885 bases
Orientation:
Minus strand

Previous Assembly
chr11:117,884,463-117,957,678
(GRCh37/hg19 by Entrez Gene)
Size:
73,216 bases
Orientation:
Minus strand

chr11:117,886,487-117,957,508
(GRCh37/hg19 by Ensembl)
Size:
71,022 bases
Orientation:
Minus strand

Genomic View for SMIM35 Gene

Genes around SMIM35 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMIM35 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMIM35 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM35 Gene

Proteins for SMIM35 Gene

  • Protein details for SMIM35 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A1B0GVV1-SIM35_HUMAN
    Recommended name:
    Small integral membrane protein 35
    Protein Accession:
    A0A1B0GVV1

    Protein attributes for SMIM35 Gene

    Size:
    85 amino acids
    Molecular mass:
    9379 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SMIM35 Gene

Post-translational modifications for SMIM35 Gene

No Post-translational modifications

Other Protein References for SMIM35 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM35 Gene

Domains & Families for SMIM35 Gene

Gene Families for SMIM35 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins
genes like me logo Genes that share domains with SMIM35: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SMIM35 Gene

Function for SMIM35 Gene

Phenotypes From GWAS Catalog for SMIM35 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMIM35 Gene

Localization for SMIM35 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM35 Gene

Membrane. Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SMIM35 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SMIM35: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SMIM35 Gene

Pathways & Interactions for SMIM35 Gene

PathCards logo

SuperPathways for SMIM35 Gene

No Data Available

Interacting Proteins for SMIM35 Gene

Gene Ontology (GO) - Biological Process for SMIM35 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SMIM35 Gene

Drugs & Compounds for SMIM35 Gene

No Compound Related Data Available

Transcripts for SMIM35 Gene

mRNA/cDNA for SMIM35 Gene

1 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM35 Gene

No ASD Table

Relevant External Links for SMIM35 Gene

GeneLoc Exon Structure for
SMIM35

Expression for SMIM35 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMIM35 Gene

Orthologs for SMIM35 Gene

Evolution for SMIM35 Gene

ENSEMBL:
Gene Tree for SMIM35 (if available)
TreeFam:
Gene Tree for SMIM35 (if available)
Alliance of Genome Resources:
Additional Orthologs for SMIM35

No data available for Orthologs for SMIM35 Gene

Paralogs for SMIM35 Gene

No data available for Paralogs for SMIM35 Gene

Variants for SMIM35 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SMIM35 Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type
877774 Uncertain Significance: Inflammatory bowel disease 28, autosomal recessive 118,000,046(-) G/A
NM_001558.4(IL10RA):c.*405G>A
NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR
877775 Uncertain Significance: Inflammatory bowel disease 28, autosomal recessive 118,000,062(-) A/C
NM_001558.4(IL10RA):c.*421A>C
NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR
877776 Uncertain Significance: Inflammatory bowel disease 28, autosomal recessive 118,000,184(-) G/A
NM_001558.4(IL10RA):c.*543G>A
NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR
877777 Uncertain Significance: Inflammatory bowel disease 28, autosomal recessive 118,000,217(-) G/C
NM_001558.4(IL10RA):c.*576G>C
NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR
878819 Uncertain Significance: Inflammatory bowel disease 28, autosomal recessive 118,000,487(-) T/A
NM_001558.4(IL10RA):c.*846T>A
NON_CODING_TRANSCRIPT_VARIANT,THREE_PRIME_UTR

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SMIM35 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SMIM35 Gene

Variant ID Type Subtype PubMed ID
esv3579922 CNV loss 25503493
esv3892103 CNV gain 25118596
esv998313 CNV insertion 20482838
nsv1049373 CNV loss 25217958
nsv1159938 CNV duplication 26073780
nsv468878 CNV gain 19166990
nsv509444 CNV insertion 20534489
nsv556463 CNV loss 21841781
nsv556464 CNV gain 21841781

Additional Variant Information for SMIM35 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMIM35
Leiden Open Variation Database (LOVD)
SMIM35

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SMIM35 Gene

Disorders for SMIM35 Gene

MalaCards: The human disease database

(3) MalaCards diseases for SMIM35 Gene - From: COP and GCD

Disorder Aliases PubMed IDs
inflammatory bowel disease 28, autosomal recessive
  • ibd28
inflammatory bowel disease 28
  • early onset autosomal recessive inflammatory bowel disease 28
sitosterolemia
  • phytosterolemia
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SMIM35

genes like me logo Genes that share disorders with SMIM35: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SMIM35 Gene

Publications for SMIM35 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4

Products for SMIM35 Gene

Sources for SMIM35 Gene