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Aliases for SMG8 Gene
Aliases for SMG8 Gene
External Ids for SMG8 Gene
- HGNC: 25551
- Entrez Gene: 55181
- Ensembl: ENSG00000167447
- OMIM: 613175
- UniProtKB: Q8ND04
Previous HGNC Symbols for SMG8 Gene
- C17orf71
Previous GeneCards Identifiers for SMG8 Gene
- GC17P057288
Summaries for SMG8 Gene
GeneCards Summary for SMG8 Gene
SMG8 (SMG8 Nonsense Mediated MRNA Decay Factor) is a Protein Coding gene. Diseases associated with SMG8 include Metaphyseal Chondrodysplasia, Schmid Type and Ullrich Congenital Muscular Dystrophy 1. Among its related pathways are Gene Expression and Viral mRNA Translation. An important paralog of this gene is ENSG00000265303.
UniProtKB/Swiss-Prot Summary for SMG8 Gene
-
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
Additional gene information for SMG8 Gene
- HGNC(25551)
- Entrez Gene(55181)
- Ensembl(ENSG00000167447)
- OMIM(613175)
- UniProtKB(Q8ND04)
- Open Targets Platform(ENSG00000167447)
- Search for SMG8 at DataMed
- Search for SMG8 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SMG8 Gene
Genomics for SMG8 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SMG8 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SMG8 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SMG8
Genomic Locations for SMG8 Gene
Genomic Locations for SMG8 Gene
- chr17:59,209,400-59,215,250
- (GRCh38/hg38)
- Size:
- 5,851 bases
- Orientation:
- Plus strand
- chr17:57,286,761-57,292,611
- (GRCh37/hg19)
- Size:
- 5,851 bases
- Orientation:
- Plus strand
Genomic View for SMG8 Gene
Genes around SMG8 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q22 by HGNC
- 17q22 by Entrez Gene
- 17q22 by Ensembl
SMG8 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SMG8 Gene
Proteins for SMG8 Gene
-
Protein details for SMG8 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8ND04-SMG8_HUMAN
- Recommended name:
- Protein SMG8
- Protein Accession:
- Q8ND04
- Q8N5U5
- Q8TDN0
- Q9H5P5
- Q9NVQ1
Protein attributes for SMG8 Gene
- Size:
- 991 amino acids
- Molecular mass:
- 109684 Da
- Quaternary structure:
-
- Component of the SMG1C complex composed of SMG1, SMG8 and SMG9; the recruitment of SMG8 to SMG1 N-terminus induces a large conformational change in the SMG1 C-terminal head domain containing the catalytic domain. Forms heterodimers with SMG9; this assembly form may represent a SMG1C intermediate form.
- SequenceCaution:
-
- Sequence=AAH20957.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=BAA91699.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
Protein Expression for SMG8 Gene
Post-translational modifications for SMG8 Gene
- Phosphorylated by SMG1.
-
Ubiquitination at Lys881
- NX_Q8ND04 (NX_Q8ND04-1)
- Modification sites at PhosphoSitePlus
Other Protein References for SMG8 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for SMG8
-
Abcam antibodies for SMG8
- Invitrogen Antibodies for SMG8 (AFLGC-SMG8)
-
Biorbyt antibodies for SMG8
- Sino Biological Antibodies for SMG8
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for SMG8
- Origene Custom Protein Services for SMG8
- Novus Biologicals proteins for SMG8
- antibodies-online: Search results for available SMG8 related products ranked by validation data
No data available for DME Specific Peptides for SMG8 Gene
Domains & Families for SMG8 Gene
Gene Families for SMG8 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for SMG8 Gene
- GenScript: Design optimal peptide antigens:
-
- Protein smg-8 homolog (SMG8_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8ND04- Family:
-
- Belongs to the SMG8 family.
Function for SMG8 Gene
Molecular function for SMG8 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
Phenotypes From GWAS Catalog for SMG8 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 19417104 |
Phenotypes for SMG8 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SMG8 - Select products 50% OFF >
- * SMG8 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SMG8
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SMG8
-
Santa Cruz Biotechnology (SCBT) CRISPR for SMG8
miRNA for SMG8 Gene
- miRTarBase miRNAs that target SMG8
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SMG8
- Browse OriGene Inhibitory RNA Products For SMG8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMG8
Clone Products
- Applied Biological Materials (abm): Clones for SMG8 - Select products 50% OFF >
- * SMG8 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SMG8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SMG8
Cell Line Products
-
Horizon Cell Lines for SMG8
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SMG8 Gene
Localization for SMG8 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 4 |
| nucleus | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| mitochondrion | 0 |
| golgi apparatus | 0 |
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for SMG8 Gene
Pathways & Interactions for SMG8 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Viral mRNA Translation | ||
| 2 | Gene Expression |
.48
|
|
Pathways by source for SMG8 Gene
3 Reactome pathways for SMG8 Gene
Interacting Proteins for SMG8 Gene
Selected Interacting proteins:
Q8ND04-SMG8_HUMAN
ENSP00000438748
for SMG8 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for SMG8
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | -- |
| GO:0045859 | regulation of protein kinase activity | IMP | 19417104 |
No data available for SIGNOR curated interactions for SMG8 Gene
Transcripts for SMG8 Gene
mRNA/cDNA for SMG8 Gene
- 1 REFSEQ mRNAs :
- 6 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000300917 3263 nts (view in UCSC)
- ENST00000543872 3477 nts (view in UCSC)
- ENST00000578922 2178 nts (view in UCSC)
- ENST00000580498 785 nts (view in UCSC)
- ENST00000580798 583 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SMG8 - Select products 50% OFF >
- * SMG8 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for SMG8
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SMG8
-
Santa Cruz Biotechnology (SCBT) CRISPR for SMG8
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SMG8
- Browse OriGene Inhibitory RNA Products For SMG8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMG8
Clone Products
- Applied Biological Materials (abm): Clones for SMG8 - Select products 50% OFF >
- * SMG8 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for SMG8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SMG8
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||
| SP2: |
Relevant External Links for SMG8 Gene
- GeneLoc Exon Structure for
- SMG8
Expression for SMG8 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (12.0), Pancreas (8.5), and Fetal Brain (7.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SMG8 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SMG8
SOURCE GeneReport for Unigene cluster for SMG8 Gene:
Hs.7296Evidence on tissue expression from TISSUES for SMG8 Gene
- Nervous system(4.8)
- Liver(4.2)
- Intestine(4.1)
Primer Products
-
OriGene qPCR primer pairs for SMG8
-
OriGene qPCR primer pairs and template standards for SMG8
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMG8 Gene
Orthologs for SMG8 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | SMG8 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | SMG8 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
| Cow (Bos Taurus) |
Mammalia | SMG8 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| Mouse (Mus musculus) |
Mammalia | Smg8 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Smg8 30 |
|
||
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| SMG8 30 |
|
||||
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | smg8 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.9776 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | smg8 30 31 |
|
OneToMany | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG6729 30 31 |
|
OneToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP010179 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | smg-8 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for SMG8 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for SMG8 Gene
- ENSEMBL:
- Gene Tree for SMG8 (if available)
- TreeFam:
- Gene Tree for SMG8 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SMG8: view image
Paralogs for SMG8 Gene
Paralogs for SMG8 Gene
Variants for SMG8 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3270n100 | CNV | gain | 25217958 |
| dgv3271n100 | CNV | gain | 25217958 |
| esv2758699 | CNV | gain | 17122850 |
| esv3573764 | CNV | gain | 25503493 |
| nsv1057152 | CNV | gain | 25217958 |
| nsv1062736 | CNV | gain | 25217958 |
| nsv1065063 | CNV | gain | 25217958 |
| nsv1065442 | CNV | gain | 25217958 |
| nsv575802 | CNV | loss | 21841781 |
| nsv833499 | CNV | loss | 17160897 |
| nsv833500 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
25.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.81;
58.41% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SMG8 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SMG8
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMG8 Gene
Disorders for SMG8 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| metaphyseal chondrodysplasia, schmid type |
|
|
| ullrich congenital muscular dystrophy 1 |
|
|
Search SMG8 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SMG8
No data available for UniProtKB/Swiss-Prot and Genatlas for SMG8 Gene
Publications for SMG8 Gene
- SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. (PMID: 19417104) Yamashita A … Ohno S (Genes & development 2009) 2 3 4
- The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8. (PMID: 21245168) Arias-Palomo E … Llorca O (Genes & development 2011) 3 4
- Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex. (PMID: 20817927) Fernández IS … Llorca O (Nucleic acids research 2011) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. (PMID: 31091453) Shami Shah A … Baskin JM (Cell reports 2019) 3
ExternalLinks
Products for SMG8 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
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- Origene Custom Protein Services for SMG8
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- Browse OriGene Inhibitory RNA Products For SMG8
- OriGene qPCR primer pairs for SMG8
- OriGene qPCR primer pairs and template standards for SMG8
- OriGene CRISPR knockouts for SMG8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For SMG8
- Sino Biological Human cDNA Clone for SMG8
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for SMG8
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Antibodies for SMG8
- Novus Biologicals proteins for SMG8
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for SMG8
- Find your target
- Browse Primary Antibodies
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- Browse Monoclonal Antibodies
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- Invitrogen Antibodies for SMG8 (AFLGC-SMG8)
- VectorBuilder Custom and pre-made DNA vectors for SMG8 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for SMG8 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Stable cell line generation for SMG8
- antibodies-online: Show 4 available SMG8 Antibodies ranked by validation data
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- antibodies-online: Search results for available SMG8 related products ranked by validation data
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- Horizon Cell Lines for SMG8
- Browse GeneCopoeia Cell Lines
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for SMG8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMG8
- Biorbyt antibodies for SMG8
Sources for SMG8 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB