Aliases for SMCR2 Gene

Data sources for SMCR2 Gene:

Subcategory (RNA class) for SMCR2 Gene

lncRNA

Aliases for SMCR2 Gene

External Ids for SMCR2 Gene

Previous GeneCards Identifiers for SMCR2 Gene

  • GC17U990313
  • GC17M017578

Summaries for SMCR2 Gene

GeneCards Summary for SMCR2 Gene

SMCR2 (Smith-Magenis Syndrome Chromosome Region, Candidate 2) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with SMCR2 include Smith-Magenis Syndrome.

Rfam classification for SMCR2 Gene

  • Smith-Magenis syndrome chromosome region, candidate 2 conserved region 2
  • Smith-Magenis syndrome chromosome region, candidate 2 conserved region 1

Additional gene information for SMCR2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SMCR2 Gene

Genomics for SMCR2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SMCR2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J017680 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 4.7 -3.3 -3281 7.2 CHD2 TBP ZBTB10 IKZF1 ZFP64 POLR2A CTCF BRCA1 BHLHE40 ZEB1 RAI1 piR-57539-002 ZNF286B LOC100419436 USP32P2 MPRIP ENSG00000260647 UPF3AP1 FAM106A TOM1L2
GH17J017662 Enhancer 1.4 Ensembl ENCODE CraniofacialAtlas dbSUPER 5.1 +17.7 17710 3.2 CTCF ZNF623 FOXA2 SMAD4 SAP130 ELF1 EBF1 KLF9 SMARCA5 SP2 DRG2 SMCR8 TOP3A PEMT FLCN ACTG1P24 TOM1L2 SMCR2 HSALNG0114970 RAI1
GH17J017675 Enhancer 1.3 Ensembl ENCODE CraniofacialAtlas dbSUPER 4.9 +4.2 4209 3 IKZF1 MCM3 IRF4 TRIM22 SMAD4 RARA ADNP PRDM10 BHLHE40 PTBP1 ENSG00000273948 ENSG00000274836 SMCR8 RPL13P12 TOM1L2 SMCR2 HSALNG0114970 HSALNG0114971 RAI1 PEMT
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SMCR2 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for SMCR2 Gene

Latest Assembly
chr17:17,673,483-17,680,910
(GRCh38/hg38)
Size:
7,428 bases
Orientation:
Minus strand

Previous Assembly
chr17:17,577,340-17,581,002
(GRCh37/hg19 by Entrez Gene)
Size:
3,663 bases
Orientation:
Minus strand

chr17:17,577,340-17,581,002
(GRCh37/hg19 by Ensembl)
Size:
3,663 bases
Orientation:
Minus strand

Genomic View for SMCR2 Gene

Genes around SMCR2 on UCSC Golden Path with GeneCards custom track
SMCR2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
SMCR2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMCR2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMCR2 Gene

Proteins for SMCR2 Gene

Post-translational modifications for SMCR2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SMCR2 Gene

Domains & Families for SMCR2 Gene

Gene Families for SMCR2 Gene

genes like me logo Genes that share domains with SMCR2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SMCR2 Gene

Function for SMCR2 Gene

Phenotypes From GWAS Catalog for SMCR2 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMCR2 Gene

Localization for SMCR2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SMCR2 Gene

Pathways & Interactions for SMCR2 Gene

PathCards logo

SuperPathways for SMCR2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SMCR2 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SMCR2 Gene

Drugs & Compounds for SMCR2 Gene

No Compound Related Data Available

Transcripts for SMCR2 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SMCR2 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00005BADDF_9606 lncRNA 568 5

RefSeq: NR_131243,

Ensembl: ENST00000456090 (view in UCSC) ,

LncBook: HSALNT0238050,

LNCipedia: SMCR2:1,

NONCODE: NONHSAT146099.2,

URS00009AE442_9606 lncRNA 564 2

LncBook: HSALNT0238051,

NONCODE: NONHSAT175994.1,

URS0000E936BD_9606 lncRNA 2733 1

LncBook: HSALNT0238047,

URS0001BD1E03_9606 lncRNA 2733 1

LncBook: HSALNT0238047,

URS0001BEB59A_9606 lncRNA 2575 1

LncBook: HSALNT0238049,

SMCR2 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for SMCR2 Gene

3 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for SMCR2 Gene

No ASD Table

Relevant External Links for SMCR2 Gene

GeneLoc Exon Structure for
SMCR2

Expression for SMCR2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SMCR2 Gene

mRNA differential expression in normal tissues according to GTEx for SMCR2 Gene

This gene is overexpressed in Testis (x10.6).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SMCR2

genes like me logo Genes that share expression patterns with SMCR2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMCR2 Gene

Orthologs for SMCR2 Gene

Evolution for SMCR2 Gene

ENSEMBL:
Gene Tree for SMCR2 (if available)
TreeFam:
Gene Tree for SMCR2 (if available)

No data available for Orthologs for SMCR2 Gene

Paralogs for SMCR2 Gene

No data available for Paralogs for SMCR2 Gene

Variants for SMCR2 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SMCR2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for SMCR2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMCR2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SMCR2 Gene

Disorders for SMCR2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SMCR2 Gene - From: GCD

Disorder Aliases PubMed IDs
smith-magenis syndrome
  • sms
- elite association - COSMIC cancer census association via MalaCards
Search SMCR2 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for SMCR2

genes like me logo Genes that share disorders with SMCR2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SMCR2 Gene

Publications for SMCR2 Gene

  1. Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse. (PMID: 11997338) Bi W … Lupski JR (Genome research 2002) 2 3

Products for SMCR2 Gene

Sources for SMCR2 Gene