Aliases for SMC2 Gene
External Ids for SMC2 Gene
Previous HGNC Symbols for SMC2 Gene
Previous GeneCards Identifiers for SMC2 Gene
GeneCards Summary for SMC2 Gene
SMC2 (Structural Maintenance Of Chromosomes 2) is a Protein Coding gene. Diseases associated with SMC2 include Pleural Empyema and Cornelia De Lange Syndrome. Among its related pathways are ATM Pathway and Mitotic Prophase. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity. An important paralog of this gene is SMC1B.
UniProtKB/Swiss-Prot Summary for SMC2 Gene
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.