This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants. [... See more...

Aliases for SMARCA1 Gene

Aliases for SMARCA1 Gene

  • SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 1 2 3 5
  • Probable Global Transcription Activator SNF2L1 3 4
  • Nucleosome-Remodeling Factor Subunit SNF2L 3 4
  • ATP-Dependent Helicase SMARCA1 3 4
  • NURF140 2 3
  • SNF2L1 3 4
  • SNF2LB 2 3
  • HSNF2L 2 3
  • SNF2L 3 4
  • ISWI 2 3
  • SWI 2 3
  • SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 1 4
  • Global Transcription Activator Homologous Sequence 3
  • Sucrose Nonfermenting 2-Like Protein 1 3
  • SNF2-Like 1 3
  • EC 3.6.4.- 4
  • EC 3.6.1 51
  • SMARCA1 5
  • SNF2LT 3
  • SWI2 3

External Ids for SMARCA1 Gene

Previous HGNC Symbols for SMARCA1 Gene

  • SNF2L1
  • SNF2L

Previous GeneCards Identifiers for SMARCA1 Gene

  • GC0XM123226
  • GC0XM125426
  • GC0XM126525
  • GC0XM127286
  • GC0XM128306
  • GC0XM128408
  • GC0XM128580
  • GC0XM117987

Summaries for SMARCA1 Gene

Entrez Gene Summary for SMARCA1 Gene

  • This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

GeneCards Summary for SMARCA1 Gene

SMARCA1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 1) is a Protein Coding gene. Diseases associated with SMARCA1 include Cockayne Syndrome and Alpha Thalassemia-X-Linked Intellectual Disability Syndrome. Among its related pathways are Platinum Pathway, Pharmacokinetics/Pharmacodynamics and BRCA1 Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and hydrolase activity. An important paralog of this gene is SMARCA5.

UniProtKB/Swiss-Prot Summary for SMARCA1 Gene

  • Energy-transducing component of NURF (nucleosome-remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes. Both complexes facilitate the perturbation of chromatin structure in an ATP-dependent manner. Potentiates neurite outgrowth. May be involved in brain development by regulating En-1 and En-2 expression. May be involved in the development of luteal cells.

Gene Wiki entry for SMARCA1 Gene

Additional gene information for SMARCA1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SMARCA1 Gene

Genomics for SMARCA1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SMARCA1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ129519 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +1.6 1593 5.1 PRDM10 ZNF629 ZSCAN4 RBFOX2 POLR2A PATZ1 ZNF740 CTCF GABPA ZNF341 SMARCA1 ENSG00000252170
GH0XJ130113 Enhancer 0.9 Ensembl ENCODE dbSUPER 9.8 -591.3 -591281 2.4 PRDM10 ZNF512 PRDM1 BCOR NR2F1 ZFP69B ZNF366 RARA ZEB2 MITF ZNF280C OCRL SMARCA1 RBMX2 AIFM1 ELF4 RAB33A RF00017-8710 RF00017-8705
GH0XJ129789 Enhancer 0.5 dbSUPER 14.9 -267.5 -267535 3.2 SCRT2 POLR2A SCRT1 ZNF112 CTCF KY994060 SMARCA1 XPNPEP2 ZDHHC9 OCRL UTP14A APLN ENSG00000240143 SASH3
GH0XJ129696 Enhancer 0.8 Ensembl ENCODE 4.6 -173.8 -173780 3 GATAD2A FOXA1 SP1 CTBP1 FOXA2 USF1 ESRRA TEAD1 CUX1 FOXP1 XPNPEP2 SMARCA1 ENSG00000287024 piR-31199-402 APLN
GH0XJ129693 Enhancer 0.7 Ensembl 4.6 -170.0 -169981 0.6 GATAD2A TFE3 RXRB SP1 CEBPA JUND SMAD4 CEBPB BCL6 HNF4A APLN SMARCA1 ENSG00000287024 piR-31199-402 XPNPEP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SMARCA1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SMARCA1

Top Transcription factor binding sites by QIAGEN in the SMARCA1 gene promoter:
  • AP-2alpha
  • AP-2alpha isoform 2
  • AP-2alpha isoform 3
  • AP-2alpha isoform 4
  • AP-2alphaA

Genomic Locations for SMARCA1 Gene

Genomic Locations for SMARCA1 Gene
chrX:129,446,501-129,523,520
(GRCh38/hg38)
Size:
77,020 bases
Orientation:
Minus strand
chrX:128,580,478-128,657,477
(GRCh37/hg19)
Size:
77,000 bases
Orientation:
Minus strand

Genomic View for SMARCA1 Gene

Genes around SMARCA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMARCA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMARCA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMARCA1 Gene

Proteins for SMARCA1 Gene

  • Protein details for SMARCA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P28370-SMCA1_HUMAN
    Recommended name:
    Probable global transcription activator SNF2L1
    Protein Accession:
    P28370
    Secondary Accessions:
    • Q5JV41
    • Q5JV42

    Protein attributes for SMARCA1 Gene

    Size:
    1054 amino acids
    Molecular mass:
    122605 Da
    Quaternary structure:
    • Part of the nucleosome-remodeling factor (NURF) complex which consists of SMARCA1; BPTF; RBBP4 and RBBP7 (PubMed:14609955). Part of the CECR2-containing-remodeling factor (CERF) complex which contains CECR2 and SMARCA1 (PubMed:15640247). Interacts with PRLR (PubMed:16740656). Interacts with ERCC6 (PubMed:26030138).
    SequenceCaution:
    • Sequence=AAA80560.1; Type=Erroneous initiation; Evidence={ECO:0000305};
    Miscellaneous:
    • [Isoform 1]: Inactive as an ATPase and a chromatin remodeler due to the presence of exon 13, but retains its ability to incorporate into the NURF complex. Predominant in non neuronal tissues.

    Alternative splice isoforms for SMARCA1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SMARCA1 Gene

Selected DME Specific Peptides for SMARCA1 Gene

P28370:
  • DDFDSWF
  • DEMGLGKT
  • PGEWDVCVTSYEM
  • QDFQFFP
  • IDEAHRIKNE
  • NRLLLTGTP
  • TGTPLQN
  • HPYLFDG
  • KSRTAME
  • ELWALLNF
  • MGLGKTL
  • LDILEDY
  • PPKRERK
  • APFHQLR
  • DSDWNPQ
  • QAMDRAHR
  • IERGEARI
  • AGGLGINL
  • QTELFAHF
  • QRRCNTLI
  • NGILADE
  • RVLIFSQM
  • LLNFLLPD
  • KRDFNQFIKANEK
  • RAHRIGQ
  • LSTRAGGLG

Post-translational modifications for SMARCA1 Gene

  • Ubiquitination at Lys179, Lys662, and Lys851
  • Modification sites at PhosphoSitePlus

Domains & Families for SMARCA1 Gene

Gene Families for SMARCA1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for SMARCA1 Gene

Suggested Antigen Peptide Sequences for SMARCA1 Gene

GenScript: Design optimal peptide antigens:
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (B1AJV0_HUMAN)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (B1ALF5_HUMAN)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1, isoform CRA_d (B7ZLQ5_HUMAN)
  • SMARCA1 protein (Q86UA8_HUMAN)
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 (SMCA1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P28370

UniProtKB/Swiss-Prot:

SMCA1_HUMAN :
  • Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
Family:
  • Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
genes like me logo Genes that share domains with SMARCA1: view

Function for SMARCA1 Gene

Molecular function for SMARCA1 Gene

UniProtKB/Swiss-Prot Function:
Energy-transducing component of NURF (nucleosome-remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes. Both complexes facilitate the perturbation of chromatin structure in an ATP-dependent manner. Potentiates neurite outgrowth. May be involved in brain development by regulating En-1 and En-2 expression. May be involved in the development of luteal cells.
GENATLAS Biochemistry:
general transcriptional activator S cerevisiae SWI/SNF related protein,matrix associated,actin-dependent regulator of chromatin,subfamily A,member 1,component of the chromatin remodeling complex,Drosophila ISWI (initiator of SWI) homolog

Enzyme Numbers (IUBMB) for SMARCA1 Gene

Phenotypes From GWAS Catalog for SMARCA1 Gene

Gene Ontology (GO) - Molecular Function for SMARCA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA,IBA 21873635
GO:0003682 chromatin binding IEA --
GO:0004386 helicase activity TAS,IEA --
genes like me logo Genes that share ontologies with SMARCA1: view
genes like me logo Genes that share phenotypes with SMARCA1: view

Animal Model Products

CRISPR Products

miRNA for SMARCA1 Gene

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMARCA1

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SMARCA1 Gene

Localization for SMARCA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMARCA1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SMARCA1 gene
Compartment Confidence
nucleus 5
cytoskeleton 2
plasma membrane 1
extracellular 1
mitochondrion 1
endoplasmic reticulum 1
cytosol 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SMARCA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IEA --
GO:0005634 nucleus IEA,IDA 14609955
GO:0005654 nucleoplasm IDA --
GO:0016589 NURF complex IEA,IDA 20850016
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with SMARCA1: view

Pathways & Interactions for SMARCA1 Gene

PathCards logo

SuperPathways for SMARCA1 Gene

SuperPathway Contained pathways
1 AMPK Enzyme Complex Pathway
.01
-
2 Chromatin Regulation / Acetylation
3 Platinum Pathway, Pharmacokinetics/Pharmacodynamics
4 BRCA1 Pathway
-
5 PEDF Induced Signaling
.43
genes like me logo Genes that share pathways with SMARCA1: view

Pathways by source for SMARCA1 Gene

1 PharmGKB pathway for SMARCA1 Gene
4 Qiagen pathways for SMARCA1 Gene
  • AMPK Enzyme Complex Pathway
  • BRCA1 Pathway
  • Chromatin Remodeling
  • Glucocorticoid Receptor Signaling
1 Cell Signaling Technology pathway for SMARCA1 Gene

Gene Ontology (GO) - Biological Process for SMARCA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000733 DNA strand renaturation IEA --
GO:0006325 chromatin organization IEA --
GO:0006338 chromatin remodeling IEA,IDA 14609955
GO:0007420 brain development IEA,IMP 14609955
GO:0016584 nucleosome positioning IBA --
genes like me logo Genes that share ontologies with SMARCA1: view

No data available for SIGNOR curated interactions for SMARCA1 Gene

Drugs & Compounds for SMARCA1 Gene

No Compound Related Data Available

Transcripts for SMARCA1 Gene

mRNA/cDNA for SMARCA1 Gene

8 REFSEQ mRNAs :
13 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SMARCA1

Alternative Splicing Database (ASD) splice patterns (SP) for SMARCA1 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^
SP1:
SP2: -
SP3:
SP4:
SP5:

ExUns: 24a · 24b · 24c ^ 25a · 25b · 25c · 25d
SP1:
SP2:
SP3:
SP4: - -
SP5: -

Relevant External Links for SMARCA1 Gene

GeneLoc Exon Structure for
SMARCA1

Expression for SMARCA1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SMARCA1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SMARCA1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (14.9), Tlymphocyte (11.4), and Fetal gut (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SMARCA1 Gene



Protein tissue co-expression partners for SMARCA1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SMARCA1

SOURCE GeneReport for Unigene cluster for SMARCA1 Gene:

Hs.152292

Evidence on tissue expression from TISSUES for SMARCA1 Gene

  • Liver(4.6)
  • Kidney(4.5)
  • Lung(4.5)
  • Nervous system(3.2)
  • Heart(2.7)
  • Blood(2.6)
  • Muscle(2.6)
  • Skin(2.5)
  • Thyroid gland(2.3)
  • Adrenal gland(2.3)
  • Intestine(2.2)
  • Spleen(2.1)
  • Eye(2.1)
genes like me logo Genes that share expression patterns with SMARCA1: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMARCA1 Gene

Orthologs for SMARCA1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SMARCA1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SMARCA1 30
  • 96.84 (n)
Dog
(Canis familiaris)
Mammalia SMARCA1 30 31
  • 94.29 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia SMARCA1 30 31
  • 93.38 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Smarca1 30
  • 91.9 (n)
Mouse
(Mus musculus)
Mammalia Smarca1 30 17 31
  • 91.78 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia SMARCA1 31
  • 91 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia SMARCA1 31
  • 87 (a)
OneToOne
Chicken
(Gallus gallus)
Aves SMARCA1 30 31
  • 82.18 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia SMARCA1 31
  • 86 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia smarca1 30
  • 78.84 (n)
Zebrafish
(Danio rerio)
Actinopterygii smarca1 31
  • 82 (a)
OneToOne
LOC559803 30
  • 74.88 (n)
Dr.12723 30
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13579 30
Fruit Fly
(Drosophila melanogaster)
Insecta Iswi 30 31 32
  • 65.37 (n)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010700 30
  • 64.75 (n)
Worm
(Caenorhabditis elegans)
Secernentea isw-1 30 31
  • 62.38 (n)
OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ISW2 30 31 33 33
  • 57.27 (n)
OneToMany
K. Lactis Yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F24838g 30
  • 56.1 (n)
A. gosspyii yeast
(Eremothecium gossypii)
Saccharomycetes AGOS_AFR537W 30
  • 55.18 (n)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.4483 30
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.6886 31
  • 70 (a)
OneToMany
Species where no ortholog for SMARCA1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for SMARCA1 Gene

ENSEMBL:
Gene Tree for SMARCA1 (if available)
TreeFam:
Gene Tree for SMARCA1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SMARCA1: view image

Paralogs for SMARCA1 Gene

(15) SIMAP similar genes for SMARCA1 Gene using alignment to 3 proteins:

  • SMCA1_HUMAN
  • B7ZLQ5_HUMAN
  • Q86UA8_HUMAN
genes like me logo Genes that share paralogs with SMARCA1: view

Variants for SMARCA1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SMARCA1 Gene

SNP ID Clinical significance and condition Chr 0X pos Variation AA Info Type
710616 Benign: not provided 129,471,259(-) C/G MISSENSE_VARIANT
722222 Benign: not provided 129,481,079(-) G/T MISSENSE_VARIANT
722474 Likely Benign: not provided 129,497,838(-) T/C INTRON_VARIANT
727875 Likely Benign: not provided 129,480,734(-) T/C SYNONYMOUS_VARIANT
739400 Likely Benign: not provided 129,468,914(-) A/C INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for SMARCA1 Gene

Structural Variations from Database of Genomic Variants (DGV) for SMARCA1 Gene

Variant ID Type Subtype PubMed ID
esv3574551 CNV loss 25503493
esv3574553 CNV loss 25503493
nsv523064 CNV gain 19592680
nsv525860 CNV gain 19592680

Variation tolerance for SMARCA1 Gene

Residual Variation Intolerance Score: 8.28% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.30; 41.08% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SMARCA1 Gene

Human Gene Mutation Database (HGMD)
SMARCA1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMARCA1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMARCA1 Gene

Disorders for SMARCA1 Gene

MalaCards: The human disease database

(12) MalaCards diseases for SMARCA1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
cockayne syndrome
  • cs
alpha thalassemia-x-linked intellectual disability syndrome
  • alpha-thalassemia/mental retardation syndrome, nondeletion type
schimke immunoosseous dysplasia
  • siod
epilepsy, familial temporal lobe, 1
  • etl1
rett syndrome
  • rtt
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with SMARCA1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SMARCA1 Gene

Publications for SMARCA1 Gene

  1. Isolation of human NURF: a regulator of Engrailed gene expression. (PMID: 14609955) Barak O … Shiekhattar R (The EMBO journal 2003) 2 3 4
  2. Cloning of human and bovine homologs of SNF2/SWI2: a global activator of transcription in yeast S. cerevisiae. (PMID: 1408766) Okabe I … Nussbaum RL (Nucleic acids research 1992) 2 3 4
  3. Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics. (PMID: 26030138) Nicolai S … Proietti-De-Santis L (PloS one 2015) 3 4
  4. Characterization of novel isoforms and evaluation of SNF2L/SMARCA1 as a candidate gene for X-linked mental retardation in 12 families linked to Xq25-26. (PMID: 18302774) Lazzaro MA … Picketts DJ (BMC medical genetics 2008) 3 23
  5. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. (PMID: 16728976) Wysocka J … Allis CD (Nature 2006) 3 23

Products for SMARCA1 Gene

Sources for SMARCA1 Gene