Aliases for SMAP1 Gene
External Ids for SMAP1 Gene
Previous GeneCards Identifiers for SMAP1 Gene
The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for SMAP1 Gene
SMAP1 (Small ArfGAP 1) is a Protein Coding gene. Diseases associated with SMAP1 include Retinitis Pigmentosa 25 and Retinitis Pigmentosa. Among its related pathways are Endocytosis. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and clathrin binding. An important paralog of this gene is SMAP2.
UniProtKB/Swiss-Prot Summary for SMAP1 Gene
GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis (By similarity).