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Aliases for SMAD5-AS1 Gene

Subcategory (RNA class) for SMAD5-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for SMAD5-AS1 Gene

  • SMAD5 Antisense RNA 1 2 3 4 5
  • SMAD5 Antisense RNA 1 (Non-Protein Coding) 2 3
  • SMAD Family Member 5 Opposite Strand 2 3
  • SMAD5OS 3 4
  • DAMS 3 4
  • 10.3 KDa Proline-Rich Protein DAMS 4
  • SMAD In The Antisense Orientation 3
  • SMAD Family Member 5, Antisense 3
  • SMAD5 Opposite Strand Protein 4
  • SMAD5AS 3

External Ids for SMAD5-AS1 Gene

Previous HGNC Symbols for SMAD5-AS1 Gene

  • SMAD5OS

Previous GeneCards Identifiers for SMAD5-AS1 Gene

  • GC05M135465

Summaries for SMAD5-AS1 Gene

GeneCards Summary for SMAD5-AS1 Gene

SMAD5-AS1 (SMAD5 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with SMAD5-AS1 include Alternating Hemiplegia Of Childhood.

Additional gene information for SMAD5-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMAD5-AS1 Gene

Genomics for SMAD5-AS1 Gene

GeneHancer (GH) Regulatory Elements for SMAD5-AS1 Gene

Promoters and enhancers for SMAD5-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I136131 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 +1.3 1267 3.3 PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF207 SMAD5 ENSG00000274934 SMAD5-AS1 ENSG00000277524 ENSG00000275646 SMIM32 GC05M136134 GC05M136114
GH05I136079 Promoter/Enhancer 1.8 FANTOM5 Ensembl ENCODE 10.3 +54.0 54033 1.7 PKNOX1 ATF1 ARNT IRF4 BRCA1 YY1 NCOA2 GTF3C2 POLR2B GATA2 ENSG00000278815 GC05M136082 VTRNA2-1 SMAD5 LECT2 SMAD5-AS1 ENSG00000277859
GH05I136013 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 9.6 +117.0 117032 9.2 PKNOX1 FOXA2 SIN3A FEZF1 FOS RXRA REST MAFF STAT3 NR2C1 LECT2 SMAD5 SMAD5-AS1 SMIM32 GC05P136010 LOC105379189
GH05I135992 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 9.8 +139.7 139735 5 JUN ATF2 SP1 JUND ATF3 POLR2A FOS FOSL2 ATF7 RCOR1 LECT2 SMAD5 IL9 ENSG00000254239 SMAD5-AS1 TGFBI SLC25A48 GC05P136002
GH05I136087 Enhancer 1 Ensembl ENCODE 10.5 +46.2 46217 3.1 HDAC1 MEIS2 LEF1 PKNOX1 ZBTB6 ZMYM3 ZBTB40 ZFHX2 CTBP1 ZNF316 SMAD5 SMAD5-AS1 LECT2 IL9 ENSG00000254239 ENSG00000278815 VTRNA2-1 ENSG00000277859
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SMAD5-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SMAD5-AS1 Gene

Genomic Locations for SMAD5-AS1 Gene
chr5:136,129,507-136,134,890
(GRCh38/hg38)
Size:
5,384 bases
Orientation:
Minus strand
chr5:135,465,196-135,470,579
(GRCh37/hg19)

Genomic View for SMAD5-AS1 Gene

Genes around SMAD5-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMAD5-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMAD5-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMAD5-AS1 Gene

Proteins for SMAD5-AS1 Gene

  • Protein details for SMAD5-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y6J3-SMA5O_HUMAN
    Recommended name:
    SMAD5 antisense gene protein 1
    Protein Accession:
    Q9Y6J3

    Protein attributes for SMAD5-AS1 Gene

    Size:
    95 amino acids
    Molecular mass:
    10312 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This protein is coded from a SMAD5 gene antisense transcript.

neXtProt entry for SMAD5-AS1 Gene

Post-translational modifications for SMAD5-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SMAD5-AS1 Gene

Domains & Families for SMAD5-AS1 Gene

Protein Domains for SMAD5-AS1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for SMAD5-AS1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMAD5-AS1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SMAD5-AS1 Gene

Function for SMAD5-AS1 Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMAD5-AS1 Gene

Localization for SMAD5-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SMAD5-AS1 Gene

Pathways & Interactions for SMAD5-AS1 Gene

SuperPathways for SMAD5-AS1 Gene

No Data Available

Interacting Proteins for SMAD5-AS1 Gene

Gene Ontology (GO) - Biological Process for SMAD5-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction TAS 10049768
genes like me logo Genes that share ontologies with SMAD5-AS1: view

No data available for Pathways by source and SIGNOR curated interactions for SMAD5-AS1 Gene

Drugs & Compounds for SMAD5-AS1 Gene

No Compound Related Data Available

Transcripts for SMAD5-AS1 Gene

mRNA/cDNA for SMAD5-AS1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMAD5-AS1 Gene

SMAD5 antisense RNA 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SMAD5-AS1 Gene

No ASD Table

Relevant External Links for SMAD5-AS1 Gene

GeneLoc Exon Structure for
SMAD5-AS1
ECgene alternative splicing isoforms for
SMAD5-AS1

Expression for SMAD5-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SMAD5-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for SMAD5-AS1 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x11.8) and Skin - Sun Exposed (Lower leg) (x8.4).

SOURCE GeneReport for Unigene cluster for SMAD5-AS1 Gene:

Hs.59666

mRNA Expression by UniProt/SwissProt for SMAD5-AS1 Gene:

Q9Y6J3-SMA5O_HUMAN
Tissue specificity: Expressed in fetal tissues.
genes like me logo Genes that share expression patterns with SMAD5-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMAD5-AS1 Gene

Orthologs for SMAD5-AS1 Gene

Evolution for SMAD5-AS1 Gene

ENSEMBL:
Gene Tree for SMAD5-AS1 (if available)
TreeFam:
Gene Tree for SMAD5-AS1 (if available)

No data available for Orthologs for SMAD5-AS1 Gene

Paralogs for SMAD5-AS1 Gene

No data available for Paralogs for SMAD5-AS1 Gene

Variants for SMAD5-AS1 Gene

Sequence variations from dbSNP and Humsavar for SMAD5-AS1 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000205842 -- 136,131,772(-) T/G intron_variant
rs1000314427 -- 136,129,057(-) A/G downstream_transcript_variant
rs1000454838 -- 136,136,445(-) A/G upstream_transcript_variant
rs1000570528 -- 136,135,175(-) A/G upstream_transcript_variant
rs1000810994 -- 136,130,092(-) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for SMAD5-AS1 Gene

Variant ID Type Subtype PubMed ID
esv2759380 CNV loss 17122850

Additional Variant Information for SMAD5-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMAD5-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SMAD5-AS1 Gene

Disorders for SMAD5-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SMAD5-AS1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
alternating hemiplegia of childhood
  • ahc
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SMAD5-AS1

genes like me logo Genes that share disorders with SMAD5-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SMAD5-AS1 Gene

Publications for SMAD5-AS1 Gene

  1. An antisense transcript to SMAD5 expressed in fetal and tumor tissues. (PMID: 10049768) Zavadil J … Nagarajan L (Biochemical and biophysical research communications 1999) 2 3 4 58

Products for SMAD5-AS1 Gene

Sources for SMAD5-AS1 Gene

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