This locus represents naturally occurring read-through transcription between the neighboring SLX1B (SLX1 structure-specific endonuclease subunit homolog B) and SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) genes on the short arm of chromosome 16. A duplicate read-through locus also exists between the SLX1A and SULT1A3 genes located approximately ... See more...

Aliases for SLX1B-SULT1A4 Gene

Data sources for SLX1B-SULT1A4 Gene:

RNA type for SLX1B-SULT1A4 Gene

lncRNA

Aliases for SLX1B-SULT1A4 Gene

External Ids for SLX1B-SULT1A4 Gene

Previous GeneCards Identifiers for SLX1B-SULT1A4 Gene

  • GC16U901288
  • GC16P029475
  • GC16P029478
  • GC16P029483

Summaries for SLX1B-SULT1A4 Gene

Entrez Gene Summary for SLX1B-SULT1A4 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring SLX1B (SLX1 structure-specific endonuclease subunit homolog B) and SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) genes on the short arm of chromosome 16. A duplicate read-through locus also exists between the SLX1A and SULT1A3 genes located approximately 730 kb downstream on the same chromosome. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2017]

GeneCards Summary for SLX1B-SULT1A4 Gene

SLX1B-SULT1A4 (SLX1B-SULT1A4 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the lncRNA class. Among its related pathways are Sulfation Biotransformation Reaction and Cytochrome P450 - arranged by substrate type.

Additional gene information for SLX1B-SULT1A4 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLX1B-SULT1A4 Gene

Genomics for SLX1B-SULT1A4 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SLX1B-SULT1A4 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J029453 Promoter/Enhancer 0.8 EPDnew Ensembl dbSUPER 250.7 -0.7 -690 3.2 BOLA2 BOLA2-SMG1P6 SLX1B SLX1B-SULT1A4 lnc-BOLA2-1 NPIPB11 NONHSAG019036.2 ENSG00000288632
GH16J029459 Promoter/Enhancer 0.8 EPDnew Ensembl dbSUPER 0.4 +5.1 5110 0.8 SULT1A4 HSALNG0110701-001 SLX1B-SULT1A4 NPIPB12 NONHSAG019036.2 ENSG00000288632
GH16J029458 Promoter/Enhancer 0.5 Ensembl dbSUPER 0.7 +2.5 2510 0.4 BOLA2 BOLA2-SMG1P6 SLX1B SLX1B-SULT1A4 SULT1A4 NONHSAG019036.2 ENSG00000288632
GH16J029457 Promoter/Enhancer 0.5 EPDnew dbSUPER 0.7 +2.8 2844 0.1 SULT1A4 BOLA2 BOLA2-SMG1P6 SLX1B SLX1B-SULT1A4 NONHSAG019036.2 ENSG00000288632
GH16J029461 Promoter/Enhancer 0.5 EPDnew dbSUPER 0.4 +6.3 6327 0.1 SULT1A4 HSALNG0110701-001 SLX1B-SULT1A4 NPIPB12 NONHSAG019036.2 ENSG00000288632
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLX1B-SULT1A4 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for SLX1B-SULT1A4 Gene

Latest Assembly
chr16:29,455,091-29,464,980
(GRCh38/hg38)
Size:
9,890 bases
Orientation:
Plus strand

Previous Assembly
chr16:29,466,412-29,476,301
(GRCh37/hg19 by Entrez Gene)
Size:
9,890 bases
Orientation:
Plus strand

chr16:29,466,412-29,476,283
(GRCh37/hg19 by Ensembl)
Size:
9,872 bases
Orientation:
Plus strand

Genomic View for SLX1B-SULT1A4 Gene

Genes around SLX1B-SULT1A4 on UCSC Golden Path with GeneCards custom track
SLX1B-SULT1A4 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
SLX1B-SULT1A4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLX1B-SULT1A4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLX1B-SULT1A4 Gene

Proteins for SLX1B-SULT1A4 Gene

Post-translational modifications for SLX1B-SULT1A4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SLX1B-SULT1A4 Gene

Domains & Families for SLX1B-SULT1A4 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SLX1B-SULT1A4 Gene

Function for SLX1B-SULT1A4 Gene

Phenotypes for SLX1B-SULT1A4 Gene

genes like me logo Genes that share phenotypes with SLX1B-SULT1A4: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLX1B-SULT1A4 Gene

Localization for SLX1B-SULT1A4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SLX1B-SULT1A4 Gene

Pathways & Interactions for SLX1B-SULT1A4 Gene

genes like me logo Genes that share pathways with SLX1B-SULT1A4: view

Pathways by source for SLX1B-SULT1A4 Gene

2 BioSystems pathways for SLX1B-SULT1A4 Gene

Gene Ontology (GO) - Biological Process for SLX1B-SULT1A4 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for SLX1B-SULT1A4 Gene

Drugs & Compounds for SLX1B-SULT1A4 Gene

No Compound Related Data Available

Transcripts for SLX1B-SULT1A4 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for SLX1B-SULT1A4 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075ABC1_9606 lncRNA 2214 1

RefSeq: NR_037609,

URS00009AD331_9606 lncRNA 2424 1

NONCODE: NONHSAT172835.1,

URS0001BD2A8A_9606 lncRNA 1140 1

LncBook: HSALNT0229512,

SLX1B-SULT1A4 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for SLX1B-SULT1A4 Gene

3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SLX1B-SULT1A4 Gene

No ASD Table

Relevant External Links for SLX1B-SULT1A4 Gene

GeneLoc Exon Structure for
SLX1B-SULT1A4

Expression for SLX1B-SULT1A4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SLX1B-SULT1A4 Gene

genes like me logo Genes that share expression patterns with SLX1B-SULT1A4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLX1B-SULT1A4 Gene

Orthologs for SLX1B-SULT1A4 Gene

Evolution for SLX1B-SULT1A4 Gene

ENSEMBL:
Gene Tree for SLX1B-SULT1A4 (if available)
TreeFam:
Gene Tree for SLX1B-SULT1A4 (if available)
Alliance of Genome Resources:
Additional Orthologs for SLX1B-SULT1A4

No data available for Orthologs for SLX1B-SULT1A4 Gene

Paralogs for SLX1B-SULT1A4 Gene

No data available for Paralogs for SLX1B-SULT1A4 Gene

Variants for SLX1B-SULT1A4 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SLX1B-SULT1A4 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SLX1B-SULT1A4 Gene

Variant ID Type Subtype PubMed ID
dgv1515e59 CNV duplication 20981092
esv22245 CNV gain 19812545
esv2714183 CNV deletion 23290073
esv2758641 CNV gain 17122850
esv2758642 CNV gain 17122850
esv29892 CNV gain 19812545
esv3333204 CNV duplication 20981092
esv3388213 CNV duplication 20981092
esv3392583 CNV duplication 20981092
esv3406739 CNV duplication 20981092
esv3444439 CNV duplication 20981092
esv3451126 CNV duplication 20981092
nsv1056249 CNV gain 25217958
nsv1078392 CNV duplication 25765185
nsv1078393 CNV duplication 25765185
nsv1139652 CNV duplication 24896259
nsv1141284 CNV duplication 24896259
nsv1146152 CNV duplication 26484159
nsv1148121 CNV duplication 26484159
nsv1150245 CNV duplication 26484159
nsv471388 CNV gain 19718026
nsv471389 CNV gain 19718026
nsv498862 CNV loss 21111241
nsv571809 CNV loss 21841781
nsv571810 CNV loss 21841781
nsv571811 CNV loss 21841781
nsv571819 CNV gain 21841781
nsv820959 CNV duplication 20802225
nsv821543 CNV duplication 20802225
nsv9426 CNV gain 18304495
nsv9431 CNV gain+loss 18304495
nsv953799 CNV deletion 24416366
nsv960011 CNV duplication 23825009
nsv977952 CNV duplication 23825009
nsv977954 CNV duplication 23825009
nsv978130 CNV duplication 23825009

Additional Variant Information for SLX1B-SULT1A4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLX1B-SULT1A4
Leiden Open Variation Database (LOVD)
SLX1B-SULT1A4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SLX1B-SULT1A4 Gene

Disorders for SLX1B-SULT1A4 Gene

Additional Disease Information for SLX1B-SULT1A4

No disorders were found for SLX1B-SULT1A4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLX1B-SULT1A4 Gene

Publications for SLX1B-SULT1A4 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3
  2. Human SULT1A3 pharmacogenetics: gene duplication and functional genomic studies. (PMID: 15358107) Hildebrandt MA … Weinshilboum RM (Biochemical and biophysical research communications 2004) 3

Products for SLX1B-SULT1A4 Gene

Sources for SLX1B-SULT1A4 Gene