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This locus represents naturally occurring read-through transcription between the neighboring SLX1A (SLX1 structure-specific endonuclease subunit homolog A) and SULT1A3 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3) genes on the short arm of chromosome 16. A duplicate read-through locus also exists between the SLX1B and SULT1A4 genes located approximately ... See more...
Aliases for SLX1A-SULT1A3 Gene
Subcategory (RNA class) for SLX1A-SULT1A3 Gene
lncRNA
Number of RNA Genes sources:
1 / 17
Aliases for SLX1A-SULT1A3 Gene
- SLX1A-SULT1A3 Readthrough (NMD Candidate) 2 3 5
- SLX1A-SULT1A3 Readthrough (Non-Protein Coding) 2 3
- Catecholamine-Sulfating Phenol Sulfotransferase 3
- Monoamine-Sulfating Phenol Sulfotransferase 3
- Sulfotransferase, Monoamine-Preferring 3
- Thermolabile Phenol Sulfotransferase 3
- Placental Estrogen Sulfotransferase 3
- Aryl Sulfotransferase 1A3/1A4 3
- Sulfotransferase 1A3/1A4 3
External Ids for SLX1A-SULT1A3 Gene
- HGNC: 44437
- Entrez Gene: 100526830
- Ensembl: ENSG00000213599
Previous GeneCards Identifiers for SLX1A-SULT1A3 Gene
- GC16U901280
- GC16P030212
- GC16P030216
- GC16P030219
- GC16P030198
- GC16P030221
- GC16P030278
- GC16P030283
- GC16P030288
- GC16P030331
- GC16P030224
- GC16P030237
- GC16P030244
- GC16P030249
- GC16P030256
- GC16P030262
- GC16P030267
- GC16P030272
Summaries for SLX1A-SULT1A3 Gene
-
This locus represents naturally occurring read-through transcription between the neighboring SLX1A (SLX1 structure-specific endonuclease subunit homolog A) and SULT1A3 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3) genes on the short arm of chromosome 16. A duplicate read-through locus also exists between the SLX1B and SULT1A4 genes located approximately 730 kb upstream on the same chromosome. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2017]
GeneCards Summary for SLX1A-SULT1A3 Gene
SLX1A-SULT1A3 (SLX1A-SULT1A3 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the lncRNA class. Among its related pathways are Sulfation Biotransformation Reaction and Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include sulfotransferase activity and aryl sulfotransferase activity.
Additional gene information for SLX1A-SULT1A3 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLX1A-SULT1A3 Gene
Genomics for SLX1A-SULT1A3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for SLX1A-SULT1A3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH16J030192 | Promoter/Enhancer | 0.8 | EPDnew Ensembl dbSUPER | 600.7 | -0.1 | -91 | 3.2 | BOLA2B SLX1A SLX1A-SULT1A3 lnc-NPIPB13-1 BOLA2 CORO1A | ||
| GH16J030119 | Promoter/Enhancer | 2.2 | EPDnew Ensembl ENCODE CraniofacialAtlas | 12.6 | -71.7 | -71721 | 5.8 | HNRNPL GATAD2A TFE3 IKZF1 KDM1A CTCF ZNF692 POLR2A RCOR2 BACH1 | MAPK3 RF00017-2045 YPEL3 SETD1A NPIPB13 NPIPB12 SRCAP ZNF747 INO80E CORO1A | |
| GH16J030112 | Promoter/Enhancer | 1.4 | EPDnew Ensembl ENCODE | 12.3 | -79.1 | -79132 | 5.7 | ARHGAP35 CEBPG HNRNPL GATAD2A CTCF ZBTB33 TEAD4 TFE3 IKZF1 NFKBIZ | GDPD3 lnc-PPP4C-12 SLX1A TBX6 SRCAP INO80E SMG1P5 SMG1P2 ENSG00000235560 MAPK3 | |
| GH16J030208 | Promoter/Enhancer | 0.8 | EPDnew Ensembl dbSUPER | 0.4 | +5.6 | 5609 | 0.6 | SULT1A3 ENSG00000278887 SLX1A-SULT1A3 NPIPB13 | ||
| GH16J030196 | Promoter/Enhancer | 0.5 | Ensembl dbSUPER | 0.7 | +3.0 | 3009 | 0.6 | BOLA2B SULT1A3 SLX1A SLX1A-SULT1A3 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SLX1A-SULT1A3 on the GeneHancer Hub at the UCSC Golden Path
Genomic Locations for SLX1A-SULT1A3 Gene
Genomic Locations for SLX1A-SULT1A3 Gene
- chr16:30,193,892-30,204,329
- (GRCh38/hg38)
- Size:
- 10,438 bases
- Orientation:
- Plus strand
- chr16:30,205,213-30,215,650
- (GRCh37/hg19)
- Size:
- 10,438 bases
- Orientation:
- Plus strand
Genomic View for SLX1A-SULT1A3 Gene
Genes around SLX1A-SULT1A3 on UCSC Golden Path with GeneCards custom track
SLX1A-SULT1A3 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
- Cytogenetic band:
-
- 16p11.2 by HGNC
- 16p11.2 by Entrez Gene
- 16p11.2 by Ensembl
SLX1A-SULT1A3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SLX1A-SULT1A3 Gene
Proteins for SLX1A-SULT1A3 Gene
Post-translational modifications for SLX1A-SULT1A3 Gene
No Post-translational modifications
Antibody Products
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SLX1A-SULT1A3
- Origene Custom Protein Services for SLX1A-SULT1A3
No data available for DME Specific Peptides for SLX1A-SULT1A3 Gene
Domains & Families for SLX1A-SULT1A3 Gene
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for SLX1A-SULT1A3 Gene
Function for SLX1A-SULT1A3 Gene
Phenotypes From GWAS Catalog for SLX1A-SULT1A3 Gene
Phenotypes for SLX1A-SULT1A3 Gene
- GenomeRNAi human phenotypes for SLX1A-SULT1A3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Browse CRISPR knockouts for SLX1A-SULT1A3
miRNA for SLX1A-SULT1A3 Gene
- miRTarBase miRNAs that target SLX1A-SULT1A3
miRNA Products
Inhibitory RNA Products
Clone Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLX1A-SULT1A3 Gene
Localization for SLX1A-SULT1A3 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SLX1A-SULT1A3 Gene
Pathways & Interactions for SLX1A-SULT1A3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytochrome P450 - arranged by substrate type | ||
| 2 | Sulfation Biotransformation Reaction | ||
Pathways by source for SLX1A-SULT1A3 Gene
2 BioSystems pathways for SLX1A-SULT1A3 Gene
No data available for Interacting Proteins and SIGNOR curated interactions for SLX1A-SULT1A3 Gene
Transcripts for SLX1A-SULT1A3 Gene
Non-coding RNA (ncRNA) Transcripts from RNAcentral for SLX1A-SULT1A3 Gene
| RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
|---|---|---|---|---|
| URS000075D98B_9606 | lncRNA | 2218 | 1 |
RefSeq: NR_037608, |
| URS0000EF5369_9606 | lncRNA | 2195 | 1 |
Ensembl: ENST00000565342 (view in UCSC) , |
| URS00009AD331_9606 | lncRNA | 2424 | 1 |
NONCODE: NONHSAT172835.1, |
SLX1A-SULT1A3 in the GeneCards ncRNA compendium hub on the UCSC Golden Path
Additional transcripts not in RNAcentral for SLX1A-SULT1A3 Gene
- 8 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000561824 1838 nts (view in UCSC)
- ENST00000566712 2380 nts (view in UCSC)
- ENST00000567520 2227 nts (view in UCSC)
- ENST00000568997 2834 nts (view in UCSC)
- ENST00000569959 2424 nts (view in UCSC)
CRISPR Products
- Browse CRISPR knockouts for SLX1A-SULT1A3
miRNA Products
Inhibitory RNA Products
Clone Products
Relevant External Links for SLX1A-SULT1A3 Gene
- GeneLoc Exon Structure for
- SLX1A-SULT1A3
Expression for SLX1A-SULT1A3 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLX1A-SULT1A3
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLX1A-SULT1A3 Gene
Orthologs for SLX1A-SULT1A3 Gene
No data available for Orthologs for SLX1A-SULT1A3 Gene
Paralogs for SLX1A-SULT1A3 Gene
No data available for Paralogs for SLX1A-SULT1A3 Gene
Variants for SLX1A-SULT1A3 Gene
Additional Variant Information for SLX1A-SULT1A3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SLX1A-SULT1A3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for SLX1A-SULT1A3 Gene
Disorders for SLX1A-SULT1A3 Gene
Additional Disease Information for SLX1A-SULT1A3
No disorders were found for SLX1A-SULT1A3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLX1A-SULT1A3 Gene
Publications for SLX1A-SULT1A3 Gene
- Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
- Human SULT1A3 pharmacogenetics: gene duplication and functional genomic studies. (PMID: 15358107) Hildebrandt MA … Weinshilboum RM (Biochemical and biophysical research communications 2004) 3
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3
- Human platelet phenolsulfotransferases: cDNA cloning, stable expression in V79 cells and identification of a novel allelic variant of the phenol-sulfating form. (PMID: 7695643) Jones AL … Glatt H (Biochemical and biophysical research communications 1995) 3
Products for SLX1A-SULT1A3 Gene
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- Custom Antibody Services
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- Custom Assay Services
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- Origene Custom Protein Services for SLX1A-SULT1A3
- Browse OriGene Inhibitory RNA Products For SLX1A-SULT1A3
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for SLX1A-SULT1A3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for SLX1A-SULT1A3
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Sources for SLX1A-SULT1A3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
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