Aliases for SLITRK5 Gene
External Ids for SLITRK5 Gene
Previous HGNC Symbols for SLITRK5 Gene
Previous GeneCards Identifiers for SLITRK5 Gene
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SLITRK5 Gene
SLITRK5 (SLIT And NTRK Like Family Member 5) is a Protein Coding gene. Diseases associated with SLITRK5 include Trichotillomania and Obsessive-Compulsive Disorder. An important paralog of this gene is SLITRK2.
UniProtKB/Swiss-Prot for SLITRK5 Gene
Suppresses neurite outgrowth.