Aliases for SLIT3 Gene
External Ids for SLIT3 Gene
Previous HGNC Symbols for SLIT3 Gene
Previous GeneCards Identifiers for SLIT3 Gene
The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
GeneCards Summary for SLIT3 Gene
SLIT3 (Slit Guidance Ligand 3) is a Protein Coding gene. Diseases associated with SLIT3 include Hepatic Adenomas, Familial and Diaphragm Disease. Among its related pathways are Development Slit-Robo signaling and Guidance Cues and Growth Cone Motility. Gene Ontology (GO) annotations related to this gene include calcium ion binding and Roundabout binding. An important paralog of this gene is SLIT2.
UniProtKB/Swiss-Prot Summary for SLIT3 Gene
May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.