Free for academic non-profit institutions. Other users need a Commercial license
SLFN13 (Schlafen Family Member 13) is a Protein Coding gene. An important paralog of this gene is SLFN11.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000049 | tRNA binding | IBA | 21873635 |
GO:0000166 | nucleotide binding | IEA | -- |
GO:0004518 | nuclease activity | IEA | -- |
GO:0004519 | endonuclease activity | IEA | -- |
GO:0004521 | endoribonuclease activity | IDA | 29563550 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005622 | intracellular | IDA | -- |
GO:0005737 | cytoplasm | IDA,IEA | 29563550 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0016075 | rRNA catabolic process | IDA | 29563550 |
GO:0016078 | tRNA catabolic process | IDA | 29563550 |
GO:0051607 | defense response to virus | IBA | 21873635 |
GO:0090305 | nucleic acid phosphodiester bond hydrolysis | IEA | -- |
GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic | IEA | -- |
ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||
SP3: | - | - | |||||||||||||||||||||||||||||||||||||
SP4: | - | - | |||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
SP6: | - | - | - | ||||||||||||||||||||||||||||||||||||
SP7: | - | - | |||||||||||||||||||||||||||||||||||||
SP8: | - | ||||||||||||||||||||||||||||||||||||||
SP9: |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | SLFN13 33 32 |
|
OneToOne | |
mouse (Mus musculus) |
Mammalia | Slfn9 17 33 32 |
|
||
Slfn8 33 |
|
ManyToMany | |||
rat (Rattus norvegicus) |
Mammalia | Slfn13 32 |
|
||
cow (Bos Taurus) |
Mammalia | -- 33 |
|
OneToMany | |
oppossum (Monodelphis domestica) |
Mammalia | -- 33 |
|
OneToMany |
SNP ID | Clin | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000028843 | -- | 35,434,724(-) | G/A | downstream_transcript_variant | |
rs1000064066 | -- | 35,446,935(-) | G/A | 5_prime_UTR_variant, intron_variant | |
rs1000181605 | -- | 35,452,026(-) | G/A | upstream_transcript_variant | |
rs1000368026 | -- | 35,446,582(-) | T/C | 5_prime_UTR_variant, intron_variant | |
rs1000390998 | -- | 35,452,640(-) | C/T | upstream_transcript_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv3142n100 | CNV | loss | 25217958 |
dgv365n27 | CNV | loss | 19166990 |
dgv5532n54 | CNV | loss | 21841781 |
dgv570e214 | CNV | loss | 21293372 |
dgv571e214 | CNV | gain | 21293372 |
dgv907e212 | CNV | loss | 25503493 |
esv2715869 | CNV | deletion | 23290073 |
esv2762399 | CNV | loss | 21179565 |
esv3892997 | CNV | gain+loss | 25118596 |
esv3892999 | CNV | loss | 25118596 |
nsv457728 | CNV | gain | 19166990 |
nsv515566 | CNV | gain+loss | 19592680 |
nsv574741 | CNV | loss | 21841781 |
nsv574743 | CNV | loss | 21841781 |
nsv574749 | CNV | gain+loss | 21841781 |
nsv962312 | CNV | duplication | 23825009 |
No disorders were found for SLFN13 Gene.