Aliases for SLFN13 Gene
External Ids for SLFN13 Gene
Previous GeneCards Identifiers for SLFN13 Gene
GeneCards Summary for SLFN13 Gene
SLFN13 (Schlafen Family Member 13) is a Protein Coding gene. An important paralog of this gene is SLFN11.
UniProtKB/Swiss-Prot Summary for SLFN13 Gene
Endoribonuclease that cleaves tRNAs and rRNAs (PubMed:29563550). Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed:29563550). Does not act on tRNA(Sec) (PubMed:29563550). Able to restrict HIV-1 virus replication; ability to inhibit HIV-1 replication is dependent on endoribonuclease activity (PubMed:29563550).