Aliases for SLCO2B1 Gene
External Ids for SLCO2B1 Gene
Previous HGNC Symbols for SLCO2B1 Gene
Previous GeneCards Identifiers for SLCO2B1 Gene
This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]
GeneCards Summary for SLCO2B1 Gene
SLCO2B1 (Solute Carrier Organic Anion Transporter Family Member 2B1) is a Protein Coding gene. Diseases associated with SLCO2B1 include Bronchiectasis 3 and Ileum Cancer. Among its related pathways are Transport of vitamins, nucleosides, and related molecules and Blood-Brain Barrier and Immune Cell Transmigration: Pathways Overview. Gene Ontology (GO) annotations related to this gene include transporter activity and sodium-independent organic anion transmembrane transporter activity. An important paralog of this gene is SLCO2A1.
UniProtKB/Swiss-Prot Summary for SLCO2B1 Gene
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost.