Aliases for SLCO2A1 Gene
External Ids for SLCO2A1 Gene
Previous HGNC Symbols for SLCO2A1 Gene
Previous GeneCards Identifiers for SLCO2A1 Gene
This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues. [provided by RefSeq, Dec 2011]
GeneCards Summary for SLCO2A1 Gene
SLCO2A1 (Solute Carrier Organic Anion Transporter Family Member 2A1) is a Protein Coding gene. Diseases associated with SLCO2A1 include Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive, 2 and Primary Hypertrophic Osteoarthropathy. Among its related pathways are Transport of vitamins, nucleosides, and related molecules and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include transporter activity and prostaglandin transmembrane transporter activity. An important paralog of this gene is SLCO2B1.
UniProtKB/Swiss-Prot Summary for SLCO2A1 Gene
May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A.