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SLCO1B7 (Solute Carrier Organic Anion Transporter Family Member 1B7 (Putative)) is a Protein Coding gene. Among its related pathways are Bile secretion. Gene Ontology (GO) annotations related to this gene include transporter activity and transmembrane transporter activity.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH12J020822 | Promoter/Enhancer | 1 | EPDnew FANTOM5 ENCODE | 0.1 | -140.3 | -140295 | 0.4 | SIN3A POLR2A | SLCO1B3 piR-36770-023 SLCO1B3-SLCO1B7 NONHSAG010647.2 ENSG00000256157 SLCO1B7 | |
GH12J020901 | Promoter | 0.3 | EPDnew | 0.2 | -61.4 | -61407 | 0.1 | SLCO1B3 lnc-SLCO1A2-5 piR-38005-006 SLCO1B7 SLCO1B3-SLCO1B7 | ||
GH12J021073 | Enhancer | 0.5 | Ensembl ENCODE | 0.1 | +111.2 | 111177 | 1.8 | CTCF JUND | SLCO1B3 piR-47211-118 ENSG00000257062 SLCO1B1 SLCO1B7 SLCO1B3-SLCO1B7 | |
GH12J020875 | Promoter | 0.3 | EPDnew | 0.2 | -87.4 | -87355 | 0.1 | SLCO1B3 piR-38005-006 SLCO1B3-SLCO1B7 lnc-SLCO1A2-5 NONHSAG010647.2 SLCO1B7 | ||
GH12J021009 | Enhancer | 0.2 | FANTOM5 | 0.3 | +46.7 | 46714 | 0 | piR-31534-123 SLCO1B3 SLCO1B1 piR-31534-124 ENSG00000257062 SLCO1B7 SLCO1B3-SLCO1B7 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0015125 | bile acid transmembrane transporter activity | IBA | 21873635 |
GO:0015347 | sodium-independent organic anion transmembrane transporter activity | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005887 | integral component of plasma membrane | IBA | 21873635 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Bile secretion |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0015721 | bile acid and bile salt transport | IBA | 21873635 |
GO:0043252 | sodium-independent organic anion transport | IBA | 21873635 |
GO:0055085 | transmembrane transport | IEA | -- |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SLCO1B7 30 |
|
||
-- 31 |
|
OneToMany | |||
Dog (Canis familiaris) |
Mammalia | OATPC 31 |
|
OneToMany | |
Cow (Bos Taurus) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Mouse (Mus musculus) |
Mammalia | Slco1b2 31 |
|
OneToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1403n100 | CNV | loss | 25217958 |
dgv1404n100 | CNV | loss | 25217958 |
dgv2401n54 | CNV | loss | 21841781 |
esv3548864 | CNV | deletion | 23714750 |
esv3580181 | CNV | loss | 25503493 |
esv3628799 | CNV | loss | 21293372 |
esv3628801 | CNV | loss | 21293372 |
nsv1035807 | CNV | loss | 25217958 |
nsv1043893 | CNV | loss | 25217958 |
nsv1054997 | CNV | gain | 25217958 |
nsv1144612 | CNV | deletion | 24896259 |
nsv1144613 | CNV | deletion | 24896259 |
nsv1159989 | CNV | duplication | 26073780 |
nsv469159 | CNV | loss | 19166990 |
nsv515735 | CNV | gain+loss | 19592680 |
nsv557718 | CNV | loss | 21841781 |
No disorders were found for SLCO1B7 Gene.