This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008] See more...

Aliases for SLCO1A2 Gene

Aliases for SLCO1A2 Gene

  • Solute Carrier Organic Anion Transporter Family Member 1A2 2 3 4 5
  • OATP1A2 2 3 4
  • OATP-A 2 3 4
  • OATP 2 3 4
  • Solute Carrier Family 21 (Organic Anion Transporter), Member 3 2 3
  • Sodium-Independent Organic Anion Transporter 3 4
  • Organic Anion-Transporting Polypeptide 1 3 4
  • Solute Carrier Family 21 Member 3 3 4
  • SLC21A3 3 4
  • OATP-1 3 4
  • Solute Carrier Organic Anion Transporter Family, Member 1A2 2
  • Organic Anion Transporting Polypeptide A 3
  • SLCO1A2 5
  • OATP1 4

External Ids for SLCO1A2 Gene

Previous HGNC Symbols for SLCO1A2 Gene

  • SLC21A3

Previous GeneCards Identifiers for SLCO1A2 Gene

  • GC12M021313
  • GC12M021417
  • GC12M021191

Summaries for SLCO1A2 Gene

Entrez Gene Summary for SLCO1A2 Gene

  • This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008]

GeneCards Summary for SLCO1A2 Gene

SLCO1A2 (Solute Carrier Organic Anion Transporter Family Member 1A2) is a Protein Coding gene. Diseases associated with SLCO1A2 include Intrahepatic Cholestasis Of Pregnancy and Cholelithiasis. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Transport of vitamins, nucleosides, and related molecules. Gene Ontology (GO) annotations related to this gene include transporter activity and organic anion transmembrane transporter activity. An important paralog of this gene is SLCO1C1.

UniProtKB/Swiss-Prot Summary for SLCO1A2 Gene

  • Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin.

Gene Wiki entry for SLCO1A2 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLCO1A2 Gene

Genomics for SLCO1A2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SLCO1A2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J021323 Promoter/Enhancer 1 EPDnew Ensembl ENCODE dbSUPER 250.2 +95.0 95009 2 POU5F1 NANOG SLCO1A2 HSALNG0089756 HSALNG0089758 IAPP lnc-SLCO1A2-1 SLCO1B1
GH12J021419 Promoter 0.9 Ensembl 250.7 +0.0 34 0.8 MNT IKZF1 NBN TAF9B SUPT5H MLLT1 NRF1 EP400 EGR1 TAF7 SLCO1A2 lnc-SLCO1A2-1 piR-45012-104 piR-49322-116 piR-46002-112 piR-57176-115 PYROXD1 IAPP
GH12J021275 Enhancer 0.2 FANTOM5 4.6 +143.6 143586 0.1 piR-60926 piR-51855-007 GYS2 SLCO1B1 SLCO1A2 SLCO1B3 KCNJ8 HSALNG0089755 IAPP lnc-SLCO1A2-1
GH12J020906 Enhancer 0.2 FANTOM5 1.8 +513.2 513174 0.3 SLCO1B1 SLCO1B3 SLCO1A2 lnc-SLCO1A2-5 piR-38005-006 SLCO1B7 SLCO1B3-SLCO1B7 HSALNG0089747
GH12J021393 Promoter 0.8 Ensembl 0.3 +24.8 24833 2 TBP IKZF1 SMAD5 TAF9B SUPT5H FOXK2 NRF1 EP400 TAF7 POLR2A piR-33432-103 piR-46002-111 piR-57176-114 SLCO1A2 lnc-SLCO1A2-1 piR-40110-127 IAPP
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLCO1A2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SLCO1A2

Top Transcription factor binding sites by QIAGEN in the SLCO1A2 gene promoter:
  • HNF-4alpha1
  • HNF-4alpha2
  • NF-kappaB
  • NF-kappaB1
  • STAT3

Genomic Locations for SLCO1A2 Gene

Latest Assembly
chr12:21,264,600-21,419,634
(GRCh38/hg38)
Size:
155,035 bases
Orientation:
Minus strand

Previous Assembly
chr12:21,417,534-21,572,568
(GRCh37/hg19 by Entrez Gene)
Size:
155,035 bases
Orientation:
Minus strand

chr12:21,417,534-21,572,528
(GRCh37/hg19 by Ensembl)
Size:
154,995 bases
Orientation:
Minus strand

Genomic View for SLCO1A2 Gene

Genes around SLCO1A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLCO1A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLCO1A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLCO1A2 Gene

Proteins for SLCO1A2 Gene

  • Protein details for SLCO1A2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P46721-SO1A2_HUMAN
    Recommended name:
    Solute carrier organic anion transporter family member 1A2
    Protein Accession:
    P46721
    Secondary Accessions:
    • Q9UGP7
    • Q9UL38

    Protein attributes for SLCO1A2 Gene

    Size:
    670 amino acids
    Molecular mass:
    74145 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLCO1A2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLCO1A2 Gene

Post-translational modifications for SLCO1A2 Gene

  • Glycosylation at Asn124, Asn135, Asn412, and Asn419
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for SLCO1A2 Gene

Domains & Families for SLCO1A2 Gene

Gene Families for SLCO1A2 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters

Protein Domains for SLCO1A2 Gene

InterPro:
Blocks:
  • Protease inhibitor, Kazal-type
  • Organic anion transporter polypeptide (OATP), N-terminal
ProtoNet:

Suggested Antigen Peptide Sequences for SLCO1A2 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ60593, highly similar to Solute carrier organic anion transporter family member 1A2 (B4DJE6_HUMAN)
  • SLCO1A2 protein (Q8IV69_HUMAN)
  • Solute carrier family 21 member 3 (SO1A2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P46721

UniProtKB/Swiss-Prot:

SO1A2_HUMAN :
  • Belongs to the organo anion transporter (TC 2.A.60) family.
Family:
  • Belongs to the organo anion transporter (TC 2.A.60) family.
genes like me logo Genes that share domains with SLCO1A2: view

Function for SLCO1A2 Gene

Molecular function for SLCO1A2 Gene

UniProtKB/Swiss-Prot Function:
Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin.

Phenotypes From GWAS Catalog for SLCO1A2 Gene

Gene Ontology (GO) - Molecular Function for SLCO1A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IEA --
GO:0008514 organic anion transmembrane transporter activity TAS 9007731
GO:0015125 bile acid transmembrane transporter activity TAS --
GO:0015347 sodium-independent organic anion transmembrane transporter activity IBA 21873635
GO:0022857 transmembrane transporter activity IEA --
genes like me logo Genes that share ontologies with SLCO1A2: view
genes like me logo Genes that share phenotypes with SLCO1A2: view

Animal Models for SLCO1A2 Gene

MGI Knock Outs for SLCO1A2:

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLCO1A2

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for SLCO1A2 Gene

Localization for SLCO1A2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLCO1A2 Gene

Cell membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SLCO1A2 gene
Compartment Confidence
plasma membrane 5
extracellular 2
mitochondrion 2
nucleus 2
endoplasmic reticulum 2
cytosol 2
cytoskeleton 1
peroxisome 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SLCO1A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IDA,TAS --
GO:0005887 integral component of plasma membrane IBA 21873635
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLCO1A2: view

Pathways & Interactions for SLCO1A2 Gene

genes like me logo Genes that share pathways with SLCO1A2: view

Gene Ontology (GO) - Biological Process for SLCO1A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006811 ion transport IEA --
GO:0015711 organic anion transport TAS 9007731
GO:0015721 bile acid and bile salt transport TAS --
GO:0043252 sodium-independent organic anion transport TAS --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLCO1A2: view

No data available for SIGNOR curated interactions for SLCO1A2 Gene

Drugs & Compounds for SLCO1A2 Gene

(104) Drugs for SLCO1A2 Gene - From: DrugBank, PharmGKB, DGIdb, IUPHAR, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Rifampicin Approved Pharma Inhibitor, Inhibition, Transporter, binder Pregnane X receptor agonist; antibiotic 490
Rocuronium Approved Pharma Transporter, substrate TGF-βR I kinase inhibitor 460
Probenecid Approved, Investigational Pharma Transporter, inhibitor 45
Bumetanide Approved Pharma Transporter, substrate NKCC cotransporter inhibitor, Na+/2Cl-/K+ (NKCC) symporter inhibitor 29
cholic acid Approved Pharma Transporter, substrate, inhibitor, inducer 0

(83) Additional Compounds for SLCO1A2 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
(3a,5b,7a)-23-Carboxy-7-hydroxy-24-norcholan-3-yl-b-D-Glucopyranosiduronic acid
  • (3a,5b,7a)-23-Carboxy-7-hydroxy-24-norcholan-3-yl-b-D-glucopyranosiduronate
  • Chenodeoxycholic acid 3-glucuronide
  • Chenodeoxycholic acid-3-b-D-glucuronide
  • Chenodeoxycholic acid-3-beta-delta-glucuronide
58814-71-4
1,3,12-Trihydroxycholan-24-oic acid
  • 1,3,12-Trihydroxycholan-24-Oate
  • 1,3,12-Trihydroxy-5b-cholanoate
  • 1,3,12-Trihydroxy-5b-cholanoic acid
  • 1,3,12-Trihydroxy-cholan-24-Oate
  • 1,3,12-Trihydroxy-cholan-24-Oic acid
63266-91-1
1,3,7,12-Tetrahydroxycholan-24-oic acid
  • 1,3,7,12-Tetrahydroxycholan-24-Oate
  • 1,3,7,12-Tetrahydroxy-cholan-24-Oate
  • 1,3,7,12-Tetrahydroxy-cholan-24-Oic acid
  • 1,3,7,12-Tetrahydroxycholanoate
  • 1,3,7,12-Tetrahydroxycholanoic acid
63266-89-7
12a-Hydroxy-3-oxocholadienic acid
  • 12a-Hydroxy-3-oxocholadienate
  • 12a-Hydroxy-3-oxo-4,6-choladien-24-Oate
  • 12a-Hydroxy-3-oxo-4,6-choladien-24-Oic acid
  • 12a-Hydroxy-3-oxo-chola-4,6-dienate
  • 12a-Hydroxy-3-oxo-chola-4,6-dienic acid
13535-96-1
12b-Hydroxy-5b-cholanoic acid
  • 12b-Hydroxy-5b-cholanoate
  • 12-Hydroxy-(5b,12b)-cholan-24-Oate
  • 12-Hydroxy-(5b,12b)-cholan-24-Oic acid
  • 12b-Hydroxy-5b-cholan-24-Oate
  • 12b-Hydroxy-5b-cholan-24-Oic acid
15173-23-6
genes like me logo Genes that share compounds with SLCO1A2: view

Transcripts for SLCO1A2 Gene

mRNA/cDNA for SLCO1A2 Gene

38 REFSEQ mRNAs :
13 NCBI additional mRNA sequence :
17 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLCO1A2

Alternative Splicing Database (ASD) splice patterns (SP) for SLCO1A2 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17
SP1: - -
SP2:
SP3: -
SP4: -

Relevant External Links for SLCO1A2 Gene

GeneLoc Exon Structure for
SLCO1A2

Expression for SLCO1A2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SLCO1A2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLCO1A2 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x8.9), Brain - Substantia nigra (x7.3), Brain - Hippocampus (x6.8), Brain - Amygdala (x6.3), Brain - Putamen (basal ganglia) (x5.0), and Brain - Hypothalamus (x4.6).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLCO1A2

SOURCE GeneReport for Unigene cluster for SLCO1A2 Gene:

Hs.46440

Evidence on tissue expression from TISSUES for SLCO1A2 Gene

  • Nervous system(4.6)
  • Liver(4.6)
  • Intestine(2.8)
  • Thyroid gland(2.2)
  • Kidney(2.2)
  • Blood(2.1)
genes like me logo Genes that share expression patterns with SLCO1A2: view

Primer products for research

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLCO1A2 Gene

Orthologs for SLCO1A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SLCO1A2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia SLCO1A2 30 31
  • 99.3 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia SLCO1A2 30
  • 89.65 (n)
OATPA 31
  • 87 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia SLCO1A2 30 31
  • 87.64 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Slco1a5 30 17 31
  • 78.11 (n)
OneToMany
Slco1a4 31
  • 73 (a)
OneToMany
Slco1a1 31
  • 69 (a)
OneToMany
Gm6614 31
  • 67 (a)
OneToMany
Slco1a6 31
  • 66 (a)
OneToMany
Gm5724 31
  • 66 (a)
OneToMany
Rat
(Rattus norvegicus)
Mammalia Slco1a5 30
  • 77.66 (n)
Oppossum
(Monodelphis domestica)
Mammalia SLCO1A2 31
  • 69 (a)
OneToOne
Chicken
(Gallus gallus)
Aves SLCO1A2 30
  • 65.53 (n)
-- 31
  • 57 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 55 (a)
OneToMany
African clawed frog
(Xenopus laevis)
Amphibia MGC68666 30
Species where no ortholog for SLCO1A2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for SLCO1A2 Gene

ENSEMBL:
Gene Tree for SLCO1A2 (if available)
TreeFam:
Gene Tree for SLCO1A2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SLCO1A2: view image

Paralogs for SLCO1A2 Gene

(13) SIMAP similar genes for SLCO1A2 Gene using alignment to 14 proteins:

  • SO1A2_HUMAN
  • B4DJE6_HUMAN
  • C9IYW8_HUMAN
  • C9JCA7_HUMAN
  • C9JG34_HUMAN
  • C9JGK7_HUMAN
  • C9JHU9_HUMAN
  • C9JSB7_HUMAN
  • C9JTF6_HUMAN
  • C9JUW6_HUMAN
  • C9K059_HUMAN
  • F5GXY6_HUMAN
  • F5H060_HUMAN
  • Q8IV69_HUMAN
genes like me logo Genes that share paralogs with SLCO1A2: view

Variants for SLCO1A2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SLCO1A2 Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
rs11568554 Benign: not provided 21,300,490(-) G/A
NM_021094.4(SLCO1A2):c.768C>T (p.Asn256=)
SYNONYMOUS
rs11568567 Benign: not provided. - 21,306,942(-) T/Ap.Asn128Tyr
NM_021094.4(SLCO1A2):c.382A>T (p.Asn128Tyr)
MISSENSE
VAR_036409 A colorectal cancer sample p.Val220Ile
rs10841795 - p.Ile13Thr
rs11568557 - p.Thr668Ser

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SLCO1A2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SLCO1A2 Gene

Variant ID Type Subtype PubMed ID
dgv1404n100 CNV loss 25217958
esv1146701 CNV insertion 17803354
esv2750499 CNV gain 17666407
esv3628799 CNV loss 21293372
esv3628806 CNV loss 21293372
nsv1040888 CNV loss 25217958
nsv1115426 CNV duplication 24896259
nsv469161 CNV loss 19166990
nsv469162 CNV loss 19166990
nsv470274 CNV loss 18288195
nsv475260 CNV novel sequence insertion 20440878
nsv515735 CNV gain+loss 19592680
nsv519603 CNV gain+loss 19592680
nsv557734 CNV loss 21841781
nsv557735 CNV loss 21841781
nsv557736 CNV loss 21841781
nsv557737 CNV loss 21841781
nsv557738 CNV loss 21841781
nsv557739 CNV loss 21841781
nsv557740 CNV loss 21841781

Variation tolerance for SLCO1A2 Gene

Residual Variation Intolerance Score: 37.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.36; 70.86% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SLCO1A2 Gene

Human Gene Mutation Database (HGMD)
SLCO1A2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLCO1A2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLCO1A2 Gene

Disorders for SLCO1A2 Gene

MalaCards: The human disease database

(9) MalaCards diseases for SLCO1A2 Gene - From: COP and GCD

Disorder Aliases PubMed IDs
intrahepatic cholestasis of pregnancy
  • gravidic intrahepatic cholestasis
cholelithiasis
aneurysmal bone cysts
  • aneurysmal bone cyst
dubin-johnson syndrome
  • djs
allan-herndon-dudley syndrome
  • ahds
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SLCO1A2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with SLCO1A2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SLCO1A2 Gene

Publications for SLCO1A2 Gene

  1. Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry. (PMID: 15632119) Lee W … Kim RB (The Journal of biological chemistry 2005) 3 4 23 41
  2. Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. (PMID: 7557095) Kullak-Ublick GA … Meier PJ (Gastroenterology 1995) 3 4 26
  3. Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. (PMID: 21685912) Höglinger GU … Schellenberg GD (Nature genetics 2011) 3 41
  4. HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms. (PMID: 20051929) Hartkoorn RC … Owen A (Pharmacogenetics and genomics 2010) 3 23
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41

Products for SLCO1A2 Gene

Sources for SLCO1A2 Gene