Aliases for SLC7A6 Gene

Aliases for SLC7A6 Gene

  • Solute Carrier Family 7 Member 6 2 3 4 5
  • Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 6 2 3
  • Cationic Amino Acid Transporter, Y+ System 3 4
  • Y(+)L-Type Amino Acid Transporter 2 3 4
  • Y+L Amino Acid Transporter 2 3 4
  • Y+LAT-2 3 4
  • Y+LAT2 3 4
  • Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 6 3
  • Amino Acid Permease 3
  • KIAA0245 4
  • LAT-2 3
  • LAT3 3

External Ids for SLC7A6 Gene

Previous GeneCards Identifiers for SLC7A6 Gene

  • GC16P058995
  • GC16P068678
  • GC16P068033
  • GC16P068076
  • GC16P068074
  • GC16P066855
  • GC16U900049
  • GC16P068298
  • GC16P054171

Summaries for SLC7A6 Gene

GeneCards Summary for SLC7A6 Gene

SLC7A6 (Solute Carrier Family 7 Member 6) is a Protein Coding gene. Diseases associated with SLC7A6 include Lysinuric Protein Intolerance and Hepatocellular Carcinoma. Among its related pathways are Cell surface interactions at the vascular wall and Basigin interactions. Gene Ontology (GO) annotations related to this gene include amino acid transmembrane transporter activity and L-amino acid transmembrane transporter activity. An important paralog of this gene is SLC7A7.

UniProtKB/Swiss-Prot Summary for SLC7A6 Gene

  • Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.

Gene Wiki entry for SLC7A6 Gene

Additional gene information for SLC7A6 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLC7A6 Gene

Genomics for SLC7A6 Gene

GeneHancer (GH) Regulatory Elements for SLC7A6 Gene

Promoters and enhancers for SLC7A6 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J068263 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 517 +1.2 1171 3.6 RXRA EP300 FOXK2 ZNF217 CTCF TCF12 NRF1 POLR2G PHF8 ZFX SLC7A6 PRMT7 ZFP90 CTCF SNTB2 ZDHHC1 SLC12A4 DUS2 TSNAXIP1 ACD
GH16J068267 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 534.2 +8.7 8742 10.7 SIN3A SP1 EP300 ZIC2 RFX1 RCOR1 TGIF2 SKI TRIM22 POLR2A SLC7A6 PRMT7 ZFP90 SLC7A6OS SNTB2 ACD DPEP2 NFATC3 THAP11 PSMB10
GH16J068279 Promoter/Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 34.4 +22.6 22631 13.5 EP300 FOXK2 SIN3A POLR2G NCOR1 FOS KDM6A TCF7 FOXA1 ZNF740 PRMT7 SLC7A6 NFATC3 SLC7A6OS RNU4-30P DUS2 RANBP10 DPEP2 PSMB10 LRRC36
GH16J068326 Enhancer 1.3 Ensembl ENCODE dbSUPER 27.3 +64.9 64925 3.7 ZNF217 CTCF ZNF10 ZIC2 CLOCK TCF7 REST RELA TGIF2 RAD21 RF00015-030 RNU4-30P PRMT7 SLC7A6 DUS2 DPEP2 piR-37170-027 L13708-003
GH16J068077 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 10.5 -178.1 -178149 16 FOXK2 HNRNPK ZNF217 EP300 ZSCAN5C SIN3A NRF1 POLR2G USF1 SP1 NFATC3 lnc-DDX28-2 CTCF E2F4 EDC4 PSKH1 ZDHHC1 ENSG00000263276 PRMT7 ENSG00000270165
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLC7A6 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SLC7A6

Top Transcription factor binding sites by QIAGEN in the SLC7A6 gene promoter:
  • C/EBPalpha
  • En-1
  • IRF-2
  • NF-1
  • SREBP-1c
  • USF-1
  • USF-1:USF-2
  • USF1
  • USF2
  • Zic3

Genomic Locations for SLC7A6 Gene

Genomic Locations for SLC7A6 Gene
chr16:68,263,830-68,301,823
(GRCh38/hg38)
Size:
37,994 bases
Orientation:
Plus strand
chr16:68,298,423-68,335,722
(GRCh37/hg19)
Size:
37,300 bases
Orientation:
Plus strand

Genomic View for SLC7A6 Gene

Genes around SLC7A6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC7A6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC7A6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC7A6 Gene

Proteins for SLC7A6 Gene

  • Protein details for SLC7A6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q92536-YLAT2_HUMAN
    Recommended name:
    Y+L amino acid transporter 2
    Protein Accession:
    Q92536
    Secondary Accessions:
    • Q68DS4
    • Q7L1N3

    Protein attributes for SLC7A6 Gene

    Size:
    515 amino acids
    Molecular mass:
    56828 Da
    Quaternary structure:
    • Disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc.
    SequenceCaution:
    • Sequence=BAA13376.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for SLC7A6 Gene

Post-translational modifications for SLC7A6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SLC7A6 Gene

Domains & Families for SLC7A6 Gene

Gene Families for SLC7A6 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters

Protein Domains for SLC7A6 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC7A6 Gene

GenScript: Design optimal peptide antigens:
  • SLC7A6 protein (A0AUM0_HUMAN)
  • y(+)L-type amino acid transporter 2 (YLAT2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q92536

UniProtKB/Swiss-Prot:

YLAT2_HUMAN :
  • Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
Family:
  • Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
genes like me logo Genes that share domains with SLC7A6: view

Function for SLC7A6 Gene

Molecular function for SLC7A6 Gene

UniProtKB/Swiss-Prot Function:
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
UniProtKB/Swiss-Prot EnzymeRegulation:
Arginine transport is strongly inhibited by lysine, glutamate, leucine, glutamine, methionine and histidine, in the presence of Na(+). Also inhibited by protein kinase C (PKC) and treatment with phorbol-12-myristate-13-acetate (PMA). Mutual inhibition is observed when leucine or glutamine is used as substrate. Inhibition of arginine and leucine uptake also occurs when SLC3A2/4F2hc is either truncated at its C-terminus or mutated at critical residues within the terminal 15 amino acids.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=295 uM for glutamine (in the presence of NaCl) {ECO:0000269 PubMed:10903140}; KM=236 uM for leucine (in the presence of NaCl) {ECO:0000269 PubMed:10903140}; KM=120 uM for arginine (in the presence of NaCl) {ECO:0000269 PubMed:10903140}; KM=138 uM for arginine (in the absence of NaCl) {ECO:0000269 PubMed:10903140};
GENATLAS Biochemistry:
solute carrier family 7,member A6,heterodimerizing with the cell surface glycoprotein to form a complex mediating y+L -type transporter exchanging cationic aminoacids and/or neutral aminoacids together with sodium,glycoprotein associated aminoacid transporter family

Phenotypes From GWAS Catalog for SLC7A6 Gene

Gene Ontology (GO) - Molecular Function for SLC7A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015171 amino acid transmembrane transporter activity TAS 9829974
GO:0015179 L-amino acid transmembrane transporter activity IBA 21873635
GO:0015297 antiporter activity IEA --
GO:0022857 transmembrane transporter activity IEA --
genes like me logo Genes that share ontologies with SLC7A6: view
genes like me logo Genes that share phenotypes with SLC7A6: view

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC7A6

CRISPR Products

miRNA for SLC7A6 Gene

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC7A6

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC7A6 Gene

Localization for SLC7A6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC7A6 Gene

Basolateral cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SLC7A6 gene
Compartment Confidence
plasma membrane 5
extracellular 2
cytoskeleton 1
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
endosome 1
cytosol 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SLC7A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IDA,TAS --
GO:0005887 integral component of plasma membrane TAS 9829974
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0016323 basolateral plasma membrane IEA --
genes like me logo Genes that share ontologies with SLC7A6: view

Pathways & Interactions for SLC7A6 Gene

genes like me logo Genes that share pathways with SLC7A6: view

Gene Ontology (GO) - Biological Process for SLC7A6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003333 amino acid transmembrane transport TAS 9829974
GO:0006865 amino acid transport TAS --
GO:0050900 leukocyte migration TAS --
GO:0055085 transmembrane transport IEA --
GO:1902475 L-alpha-amino acid transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC7A6: view

No data available for SIGNOR curated interactions for SLC7A6 Gene

Drugs & Compounds for SLC7A6 Gene

(3) Drugs for SLC7A6 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ornithine Approved Nutra 78
Arginine Investigational Nutra Full agonist, Agonist 587

(2) Additional Compounds for SLC7A6 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
sodium
  • Na(+)
  • Na+
  • SODIUM ion
7440-23-5
genes like me logo Genes that share compounds with SLC7A6: view

Transcripts for SLC7A6 Gene

mRNA/cDNA for SLC7A6 Gene

2 REFSEQ mRNAs :
11 NCBI additional mRNA sequence :
17 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC7A6

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC7A6 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14 ^
SP1:
SP2: -
SP3: - - - -
SP4:
SP5: - -
SP6: - -
SP7: -
SP8: - -
SP9:
SP10: - - -
SP11: - - -
SP12: - -
SP13: - - - -

ExUns: 15 ^ 16
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for SLC7A6 Gene

GeneLoc Exon Structure for
SLC7A6

Expression for SLC7A6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SLC7A6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC7A6 Gene

This gene is overexpressed in Muscle - Skeletal (x9.2).

Protein differential expression in normal tissues from HIPED for SLC7A6 Gene

This gene is overexpressed in Placenta (57.2) and Bone (11.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SLC7A6 Gene



Protein tissue co-expression partners for SLC7A6 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLC7A6

SOURCE GeneReport for Unigene cluster for SLC7A6 Gene:

Hs.679580

mRNA Expression by UniProt/SwissProt for SLC7A6 Gene:

Q92536-YLAT2_HUMAN
Tissue specificity: Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, RPE cells, and various carcinoma cell lines.

Evidence on tissue expression from TISSUES for SLC7A6 Gene

  • Nervous system(3.1)
  • Lung(2.1)
  • Intestine(2)
genes like me logo Genes that share expression patterns with SLC7A6: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC7A6 Gene

Orthologs for SLC7A6 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLC7A6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC7A6 31 30
  • 99.74 (n)
OneToOne
dog
(Canis familiaris)
Mammalia SLC7A6 31 30
  • 91.18 (n)
OneToOne
cow
(Bos Taurus)
Mammalia SLC7A6 31 30
  • 89.97 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Slc7a6 17 31 30
  • 89.32 (n)
rat
(Rattus norvegicus)
Mammalia Slc7a6 30
  • 89.26 (n)
oppossum
(Monodelphis domestica)
Mammalia SLC7A6 31
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SLC7A6 31
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves SLC7A6 31 30
  • 72.18 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC7A6 31
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc7a6 30
  • 68.47 (n)
zebrafish
(Danio rerio)
Actinopterygii slc7a6 31 30
  • 72.44 (n)
OneToOne
Dr.18441 30
fruit fly
(Drosophila melanogaster)
Insecta CG1607 30
  • 57.19 (n)
mnd 31 32
  • 48 (a)
ManyToMany
JhI-21 31 32
  • 44 (a)
ManyToMany
CG6070 32
  • 44 (a)
gb 31
  • 42 (a)
ManyToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP001627 30
  • 55.29 (n)
worm
(Caenorhabditis elegans)
Secernentea aat-1 30
  • 51.95 (n)
F52H2.2 32
  • 46 (a)
aat-2 31
  • 45 (a)
OneToMany
F27C8.1 32
  • 45 (a)
F07C3.7 32
  • 44 (a)
T13A10.10 32
  • 35 (a)
Y53H1C.1 32
  • 35 (a)
C55C2.5a 32
  • 33 (a)
C55C2.5b 32
  • 33 (a)
T11F9.4 32
  • 33 (a)
F54D12.3 32
  • 32 (a)
F28F9.4 32
  • 28 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 54 (a)
OneToMany
Cin.4067 30
bread mold
(Neurospora crassa)
Ascomycetes NCU03815 30
  • 49.11 (n)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.4067 30
Species where no ortholog for SLC7A6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC7A6 Gene

ENSEMBL:
Gene Tree for SLC7A6 (if available)
TreeFam:
Gene Tree for SLC7A6 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SLC7A6: view image

Paralogs for SLC7A6 Gene

(14) SIMAP similar genes for SLC7A6 Gene using alignment to 12 proteins:

  • YLAT2_HUMAN
  • A0AUM0_HUMAN
  • E7EPZ8_HUMAN
  • H3BNF5_HUMAN
  • H3BPK5_HUMAN
  • H3BPV6_HUMAN
  • H3BRZ8_HUMAN
  • H3BSB6_HUMAN
  • H3BSV7_HUMAN
  • H3BUA4_HUMAN
  • H3BUR2_HUMAN
  • J3QL60_HUMAN

Pseudogenes.org Pseudogenes for SLC7A6 Gene

genes like me logo Genes that share paralogs with SLC7A6: view

Variants for SLC7A6 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SLC7A6 Gene

SNP ID Clinical significance and condition Chr 16 pos Variation AA Info Type
719412 Likely Benign: not provided 68,296,494(+) A/G MISSENSE_VARIANT
777037 Benign: not provided 68,291,300(+) T/A MISSENSE_VARIANT
777038 Benign: not provided 68,296,727(+) T/C MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for SLC7A6 Gene

Structural Variations from Database of Genomic Variants (DGV) for SLC7A6 Gene

Variant ID Type Subtype PubMed ID
esv2675923 CNV deletion 23128226
esv3638904 CNV loss 21293372
nsv510691 CNV deletion 20534489

Variation tolerance for SLC7A6 Gene

Residual Variation Intolerance Score: 46.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.65; 56.87% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SLC7A6 Gene

Human Gene Mutation Database (HGMD)
SLC7A6
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC7A6

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC7A6 Gene

Disorders for SLC7A6 Gene

MalaCards: The human disease database

(2) MalaCards diseases for SLC7A6 Gene - From: LncRNADisease, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SLC7A6

genes like me logo Genes that share disorders with SLC7A6: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SLC7A6 Gene

Publications for SLC7A6 Gene

  1. Human metabolic individuality in biomedical and pharmaceutical research. (PMID: 21886157) Suhre K … Gieger C (Nature 2011) 3 41 54
  2. Activation of classical protein kinase C decreases transport via systems y+ and y+L. (PMID: 17329401) Rotmann A … Closs EI (American journal of physiology. Cell physiology 2007) 4 23 54
  3. A y(+)LAT-1 mutant protein interferes with y(+)LAT-2 activity: implications for the molecular pathogenesis of lysinuric protein intolerance. (PMID: 15756301) Sperandeo MP … Sebastio G (European journal of human genetics : EJHG 2005) 4 23 54
  4. The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine. (PMID: 10903140) Bröer A … Bröer S (The Biochemical journal 2000) 3 4 54
  5. Arginine transport through system y(+)L in cultured human fibroblasts: normal phenotype of cells from LPI subjects. (PMID: 11078698) Dall'Asta V … Gazzola GC (American journal of physiology. Cell physiology 2000) 4 23 54

Products for SLC7A6 Gene

Sources for SLC7A6 Gene