Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SLC7A5P2 Gene

Aliases for SLC7A5P2 Gene

  • Solute Carrier Family 7 Member 5 Pseudogene 2 2 3 5
  • Solute Carrier Family 7 (Amino Acid Transporter Light Chain, L System), Member 5 Pseudogene 2 2 3
  • IMAA 3 4
  • MMAA 3 4
  • Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 Pseudogene 2 3
  • HLAT1 3-Transmembrane Protein IMAA 4
  • HLAT1 3-Transmembrane Protein MMAA 4
  • LAT1-3TM Protein 2 3
  • SLC7A5 Pseudogene 3
  • HLAT1 3TM IMAA 4
  • HLAT1 3TM MMAA 4
  • HLAT1-3TM 3

External Ids for SLC7A5P2 Gene

Previous GeneCards Identifiers for SLC7A5P2 Gene

  • GC16M021529

Summaries for SLC7A5P2 Gene

GeneCards Summary for SLC7A5P2 Gene

SLC7A5P2 (Solute Carrier Family 7 Member 5 Pseudogene 2) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include amino acid transmembrane transporter activity.

Additional gene information for SLC7A5P2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC7A5P2 Gene

Genomics for SLC7A5P2 Gene

GeneHancer (GH) Regulatory Elements for SLC7A5P2 Gene

Promoters and enhancers for SLC7A5P2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I021517 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 550.8 +0.2 215 4.7 HDGF PKNOX1 CLOCK FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 SMG1P3 SLC7A5P2 THUMPD1 RRN3P1 NPIPB4 NPIPB3 NPIPB5 C16orf52 SMG1P1 ENSG00000260635
GH16I021515 Enhancer 1 ENCODE dbSUPER 0.8 +4.7 4738 0.6 PKNOX1 FOXA2 INSM2 MZF1 FEZF1 RFX5 ZEB1 GLIS2 ZNF366 ZSCAN5C PIR36552 SLC7A5P2 SMG1P3
GH16I021518 Enhancer 0.8 dbSUPER 0.8 +3.1 3118 0.5 HDAC1 HDGF SMAD1 RB1 INSM2 KLF17 ZBTB40 ZNF2 ZNF213 SCRT2 PIR36552 SLC7A5P2 SMG1P3
GH16I021516 Enhancer 0.6 dbSUPER 0.8 +4.2 4181 0.5 HDGF SCRT1 NR2F1 ZNF384 ZFP69B ZNF366 ZBTB48 BCL6B PRDM10 MLLT1 PIR36552 SMG1P3 SLC7A5P2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SLC7A5P2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for SLC7A5P2 Gene

Genomic Locations for SLC7A5P2 Gene
chr16:21,517,893-21,520,444
(GRCh38/hg38)
Size:
2,552 bases
Orientation:
Minus strand
chr16:21,529,214-21,531,765
(GRCh37/hg19)

Genomic View for SLC7A5P2 Gene

Genes around SLC7A5P2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC7A5P2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC7A5P2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC7A5P2 Gene

Proteins for SLC7A5P2 Gene

  • Protein details for SLC7A5P2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GIP4-LAT1L_HUMAN
    Recommended name:
    Putative L-type amino acid transporter 1-like protein IMAA
    Protein Accession:
    Q9GIP4
    Secondary Accessions:
    • Q6IPZ0
    • Q8MH62

    Protein attributes for SLC7A5P2 Gene

    Size:
    190 amino acids
    Molecular mass:
    19840 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLC7A5P2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC7A5P2 Gene

Post-translational modifications for SLC7A5P2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SLC7A5P2 Gene

Domains & Families for SLC7A5P2 Gene

Protein Domains for SLC7A5P2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC7A5P2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9GIP4

UniProtKB/Swiss-Prot:

LAT1L_HUMAN :
  • Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
Family:
  • Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
genes like me logo Genes that share domains with SLC7A5P2: view

No data available for Gene Families for SLC7A5P2 Gene

Function for SLC7A5P2 Gene

Molecular function for SLC7A5P2 Gene

UniProtKB/Swiss-Prot Induction:
Up-regulated by concanavalin-A stimulation.

Gene Ontology (GO) - Molecular Function for SLC7A5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015175 neutral amino acid transmembrane transporter activity IBA --
GO:0015179 L-amino acid transmembrane transporter activity IBA --
GO:0015297 antiporter activity IBA --
genes like me logo Genes that share ontologies with SLC7A5P2: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SLC7A5P2 Gene

Localization for SLC7A5P2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC7A5P2 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC7A5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
genes like me logo Genes that share ontologies with SLC7A5P2: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SLC7A5P2 Gene

Pathways & Interactions for SLC7A5P2 Gene

SuperPathways for SLC7A5P2 Gene

No Data Available

Interacting Proteins for SLC7A5P2 Gene

Gene Ontology (GO) - Biological Process for SLC7A5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015804 neutral amino acid transport IBA --
GO:1902475 L-alpha-amino acid transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC7A5P2: view

No data available for Pathways by source and SIGNOR curated interactions for SLC7A5P2 Gene

Drugs & Compounds for SLC7A5P2 Gene

No Compound Related Data Available

Transcripts for SLC7A5P2 Gene

mRNA/cDNA for SLC7A5P2 Gene

(2) Additional mRNA sequences :
(29) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SLC7A5P2 Gene

Solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 2:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC7A5P2 Gene

No ASD Table

Relevant External Links for SLC7A5P2 Gene

GeneLoc Exon Structure for
SLC7A5P2
ECgene alternative splicing isoforms for
SLC7A5P2

Expression for SLC7A5P2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SLC7A5P2 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SLC7A5P2 Gene



NURSA nuclear receptor signaling pathways regulating expression of SLC7A5P2 Gene:

SLC7A5P2

SOURCE GeneReport for Unigene cluster for SLC7A5P2 Gene:

Hs.664952

mRNA Expression by UniProt/SwissProt for SLC7A5P2 Gene:

Q9GIP4-LAT1L_HUMAN
Tissue specificity: Expressed in peripheral blood mononuclear cells and lymphoid and myeloid cell lines.
genes like me logo Genes that share expression patterns with SLC7A5P2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC7A5P2 Gene

Orthologs for SLC7A5P2 Gene

Evolution for SLC7A5P2 Gene

ENSEMBL:
Gene Tree for SLC7A5P2 (if available)
TreeFam:
Gene Tree for SLC7A5P2 (if available)

No data available for Orthologs for SLC7A5P2 Gene

Paralogs for SLC7A5P2 Gene

(9) SIMAP similar genes for SLC7A5P2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SLC7A5P2: view

No data available for Paralogs for SLC7A5P2 Gene

Variants for SLC7A5P2 Gene

Sequence variations from dbSNP and Humsavar for SLC7A5P2 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000083669 -- 21,521,161(-) G/T upstream_transcript_variant
rs1008865018 -- 21,521,308(-) T/C upstream_transcript_variant
rs1009413779 -- 21,521,792(-) T/C upstream_transcript_variant
rs1010054382 -- 21,521,233(-) A/G upstream_transcript_variant
rs1014189661 -- 21,518,664(-) G/A non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SLC7A5P2 Gene

Variant ID Type Subtype PubMed ID
dgv1316n106 CNV duplication 24896259
dgv2800n100 CNV gain 25217958
dgv2801n100 CNV loss 25217958
dgv466n67 CNV gain 20364138
dgv489e214 CNV gain 21293372
dgv4944n54 CNV loss 21841781
esv2421840 CNV deletion 20811451
esv25717 CNV gain+loss 19812545
esv2651779 CNV gain 19546169
esv2758636 CNV gain+loss 17122850
esv2762010 CNV gain+loss 21179565
esv2763135 CNV gain 21179565
esv33799 CNV loss 17666407
esv34235 CNV gain 17911159
esv3584705 CNV loss 24956385
esv3638168 CNV loss 21293372
esv3892810 CNV loss 25118596
nsv1076422 CNV duplication 25765185
nsv1152437 CNV duplication 26484159
nsv1160372 CNV duplication 26073780
nsv428322 CNV gain 18775914
nsv433437 CNV gain 18776910
nsv433438 CNV gain 18776910
nsv442716 CNV gain 18776908
nsv509606 CNV insertion 20534489
nsv827584 CNV gain 20364138
nsv827589 CNV loss 20364138
nsv9397 CNV gain+loss 18304495
nsv977934 CNV duplication 23825009

Additional Variant Information for SLC7A5P2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC7A5P2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SLC7A5P2 Gene

Disorders for SLC7A5P2 Gene

Additional Disease Information for SLC7A5P2

No disorders were found for SLC7A5P2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC7A5P2 Gene

Publications for SLC7A5P2 Gene

  1. Up-regulated expression of a novel gene in activated human peripheral blood mononuclear cells that is a truncated paralog of the human system L-amino acid transporter 1. (PMID: 12009310) Ito M … Tsurudome M (The international journal of biochemistry & cell biology 2002) 2 3 4 58
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  4. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3

Products for SLC7A5P2 Gene

Sources for SLC7A5P2 Gene

Content
Loading form....