This locus represents a pseudogene of the L-type amino acid transporter 1. Transcripts initiating at this locus read through to downstream SMG1 pseudogene 2 (SMG1P2). [provided by RefSeq, Feb 2016] See more...

Aliases for SLC7A5P1 Gene

Aliases for SLC7A5P1 Gene

  • Solute Carrier Family 7 Member 5 Pseudogene 1 2 3 5
  • MLAS 2 3 4
  • Solute Carrier Family 7 (Amino Acid Transporter Light Chain, L System), Member 5 Pseudogene 1 2 3
  • Putative L-Type Amino Acid Transporter 1-Like Protein MLAS 3 4
  • HLAT1 3-Transmembrane Protein MLAS 3 4
  • LAT1-3TM 2 3
  • Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 Pseudogene 1 3
  • SLC7A5 Pseudogene 3
  • HLAT1 3TM MLAS 4
  • HLAT1-3TM 3
  • SLC7A5P1 5
  • DC49 3

External Ids for SLC7A5P1 Gene

Previous GeneCards Identifiers for SLC7A5P1 Gene

  • GC16M029533
  • GC16M029534
  • GC16M029627
  • GC16M029652

Summaries for SLC7A5P1 Gene

Entrez Gene Summary for SLC7A5P1 Gene

  • This locus represents a pseudogene of the L-type amino acid transporter 1. Transcripts initiating at this locus read through to downstream SMG1 pseudogene 2 (SMG1P2). [provided by RefSeq, Feb 2016]

GeneCards Summary for SLC7A5P1 Gene

SLC7A5P1 (Solute Carrier Family 7 Member 5 Pseudogene 1) is a Pseudogene.

Additional gene information for SLC7A5P1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLC7A5P1 Gene

Genomics for SLC7A5P1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for SLC7A5P1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J029609 Promoter/Enhancer 2 Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +0.4 425 7.4 RNF2 ARHGAP35 SP1 ATF7 TEAD4 PRDM10 ZNF692 POLR2A BACH1 LARP7 SMG1P2 SLC7A5P1 piR-38472-002 INO80E ATXN2L ENSG00000261766 NPIPB12 SH2B1 NPIPB13 SPNS1
GH16J029114 Promoter/Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 4.7 +497.7 497652 3 GATAD2A CTCF ZNF629 LEF1 IKZF1 ZNF692 TARDBP PRDM1 ZIC2 REST SPNS1 RRN3P2 NPIPB12 ENSG00000260853 ENSG00000260908 INO80E ATXN2L SMG1P2 NFATC2IP ENSG00000198106
GH16J029106 Promoter 0.7 Ensembl 6 +506.3 506324 1.2 PKNOX1 ZNF444 CREB1 YY1 MAZ MNT CTCF EZH2 ENSG00000260908 LOC101928215 piR-37142-006 lnc-RABEP2-5 RRN3P2 ENSG00000260517 SLC7A5P1 LOC107984832 LAT
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLC7A5P1 on the GeneHancer Hub at the UCSC Golden Path

Top Transcription factor binding sites by QIAGEN in the SLC7A5P1 gene promoter:
  • Arnt
  • HOXA9
  • HOXA9B
  • Ik-3
  • MZF-1
  • Olf-1
  • Pax-3
  • Pax-4a
  • Pax-5
  • STAT3

Genomic Locations for SLC7A5P1 Gene

Genomic Locations for SLC7A5P1 Gene
chr16:29,613,103-29,613,725
(GRCh38/hg38)
Size:
623 bases
Orientation:
Minus strand
chr16:29,624,424-29,625,038
(GRCh37/hg19)
Size:
615 bases
Orientation:
Minus strand

Genomic View for SLC7A5P1 Gene

Genes around SLC7A5P1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC7A5P1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC7A5P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC7A5P1 Gene

Proteins for SLC7A5P1 Gene

  • Protein details for SLC7A5P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8MH63-LAT1N_HUMAN
    Recommended name:
    Putative L-type amino acid transporter 1-like protein MLAS
    Protein Accession:
    Q8MH63

    Protein attributes for SLC7A5P1 Gene

    Size:
    180 amino acids
    Molecular mass:
    18779 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SLC7A5P1 Gene

Post-translational modifications for SLC7A5P1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SLC7A5P1 Gene

Domains & Families for SLC7A5P1 Gene

Protein Domains for SLC7A5P1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLC7A5P1 Gene

GenScript: Design optimal peptide antigens:
  • hLAT1 3-transmembrane protein MLAS (LAT1N_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8MH63

UniProtKB/Swiss-Prot:

LAT1N_HUMAN :
  • Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
Family:
  • Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
genes like me logo Genes that share domains with SLC7A5P1: view

No data available for Gene Families for SLC7A5P1 Gene

Function for SLC7A5P1 Gene

Phenotypes From GWAS Catalog for SLC7A5P1 Gene

Gene Ontology (GO) - Molecular Function for SLC7A5P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015179 L-amino acid transmembrane transporter activity IBA 21873635
genes like me logo Genes that share ontologies with SLC7A5P1: view
genes like me logo Genes that share phenotypes with SLC7A5P1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLC7A5P1 Gene

Localization for SLC7A5P1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC7A5P1 Gene

Membrane. Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SLC7A5P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC7A5P1: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for SLC7A5P1 Gene

Pathways & Interactions for SLC7A5P1 Gene

PathCards logo

SuperPathways for SLC7A5P1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SLC7A5P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003333 amino acid transmembrane transport IBA 21873635
GO:1902475 L-alpha-amino acid transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC7A5P1: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for SLC7A5P1 Gene

Drugs & Compounds for SLC7A5P1 Gene

No Compound Related Data Available

Transcripts for SLC7A5P1 Gene

mRNA/cDNA for SLC7A5P1 Gene

1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SLC7A5P1 Gene

No ASD Table

Relevant External Links for SLC7A5P1 Gene

GeneLoc Exon Structure for
SLC7A5P1

Expression for SLC7A5P1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SLC7A5P1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLC7A5P1

SOURCE GeneReport for Unigene cluster for SLC7A5P1 Gene:

Hs.677169

mRNA Expression by UniProt/SwissProt for SLC7A5P1 Gene:

Q8MH63-LAT1N_HUMAN
Tissue specificity: Expressed in peripheral blood mononuclear cells and lymphoid and myeloid cell lines.
genes like me logo Genes that share expression patterns with SLC7A5P1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC7A5P1 Gene

Orthologs for SLC7A5P1 Gene

Evolution for SLC7A5P1 Gene

ENSEMBL:
Gene Tree for SLC7A5P1 (if available)
TreeFam:
Gene Tree for SLC7A5P1 (if available)

No data available for Orthologs for SLC7A5P1 Gene

Paralogs for SLC7A5P1 Gene

(10) SIMAP similar genes for SLC7A5P1 Gene using alignment to 1 proteins:

  • LAT1N_HUMAN
genes like me logo Genes that share paralogs with SLC7A5P1: view

No data available for Paralogs for SLC7A5P1 Gene

Variants for SLC7A5P1 Gene

Structural Variations from Database of Genomic Variants (DGV) for SLC7A5P1 Gene

Variant ID Type Subtype PubMed ID
esv2758641 CNV gain 17122850
esv29892 CNV gain 19812545
esv32773 CNV loss 17666407
nsv1056249 CNV gain 25217958
nsv9430 CNV gain 18304495
nsv978128 CNV duplication 23825009

Additional Variant Information for SLC7A5P1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC7A5P1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) and Variation tolerance for SLC7A5P1 Gene

Disorders for SLC7A5P1 Gene

Additional Disease Information for SLC7A5P1

No disorders were found for SLC7A5P1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLC7A5P1 Gene

Publications for SLC7A5P1 Gene

  1. Up-regulated expression of a novel gene in activated human peripheral blood mononuclear cells that is a truncated paralog of the human system L-amino acid transporter 1. (PMID: 12009310) Ito M … Tsurudome M (The international journal of biochemistry & cell biology 2002) 2 3 4
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for SLC7A5P1 Gene

Sources for SLC7A5P1 Gene