Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SLC6A9 Gene

Aliases for SLC6A9 Gene

  • Solute Carrier Family 6 Member 9 2 3 4 5
  • Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 9 2 3
  • Sodium- And Chloride-Dependent Glycine Transporter 1 3 4
  • GlyT-1 3 4
  • GCENSG 3
  • GLYT1 3
  • GlyT1 4

External Ids for SLC6A9 Gene

Previous GeneCards Identifiers for SLC6A9 Gene

  • GC01M044301
  • GC01M043463
  • GC01M043891
  • GC01M043876
  • GC01M044132
  • GC01M044462
  • GC01M042577

Summaries for SLC6A9 Gene

Entrez Gene Summary for SLC6A9 Gene

  • The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by this gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. [provided by RefSeq, Jun 2016]

GeneCards Summary for SLC6A9 Gene

SLC6A9 (Solute Carrier Family 6 Member 9) is a Protein Coding gene. Diseases associated with SLC6A9 include Glycine Encephalopathy With Normal Serum Glycine and Atypical Glycine Encephalopathy. Among its related pathways are Synaptic vesicle cycle and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include neurotransmitter:sodium symporter activity and amino acid:sodium symporter activity. An important paralog of this gene is SLC6A5.

UniProtKB/Swiss-Prot for SLC6A9 Gene

  • Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.

Tocris Summary for SLC6A9 Gene

  • Glycine transporters (GlyTs) belong to a family of high affinity Na+- and Cl--dependent neurotransmitter transporters proteins. There are two subtypes of glycine transporters; GlyT1 and GlyT2. GlyT1s are predominantly located on glia within caudal brain areas.

Gene Wiki entry for SLC6A9 Gene

Additional gene information for SLC6A9 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC6A9 Gene

Genomics for SLC6A9 Gene

GeneHancer (GH) Regulatory Elements for SLC6A9 Gene

Promoters and enhancers for SLC6A9 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J044027 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 600.7 +1.0 989 5 SP1 ZFX MNT CBFA2T2 ZNF148 NKRF MLLT1 CEBPG ZNF687 CDC5L SLC6A9 ENSG00000230615 IPO13 DPH2 ARTN CCDC24 B4GALT2
GH01J044017 Promoter/Enhancer 0.9 EPDnew Ensembl dbSUPER 600.4 +14.8 14791 1.4 SLC6A9 ATP6V0B CCDC24 ENSG00000230615
GH01J043990 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 12.1 +39.7 39744 2.7 MNT ZNF148 NKRF POLR2A ELF1 SP1 SP5 PRDM1 GLIS2 GMEB1 CCDC24 SLC6A9 ARTN B4GALT2 ENSG00000230615
GH01J044507 Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 16.9 -476.3 -476328 1.4 ZIC2 EZH2 ZFHX2 SIN3A EGR2 ZNF133 RNF220 SLC6A9 ARMH1 PTCH2 MIR5584
GH01J044067 Enhancer 1 Ensembl ENCODE 11.9 -39.6 -39609 8.2 ZNF652 CBFA2T2 ZNF121 NCOA3 SP7 RELA SP1 PRDM1 EGR1 SMARCA4 SLC6A9 ARTN ERI3 ENSG00000230615 ATP6V0B ENSG00000227163 KLF17
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLC6A9 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SLC6A9 gene promoter:
  • CUTL1
  • GATA-2
  • Lmo2
  • MRF-2
  • MZF-1
  • NCX
  • Zic3

Genomic Locations for SLC6A9 Gene

Genomic Locations for SLC6A9 Gene
chr1:43,991,500-44,031,492
(GRCh38/hg38)
Size:
39,993 bases
Orientation:
Minus strand
chr1:44,457,172-44,497,139
(GRCh37/hg19)
Size:
39,968 bases
Orientation:
Minus strand

Genomic View for SLC6A9 Gene

Genes around SLC6A9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC6A9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC6A9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC6A9 Gene

Proteins for SLC6A9 Gene

  • Protein details for SLC6A9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P48067-SC6A9_HUMAN
    Recommended name:
    Sodium- and chloride-dependent glycine transporter 1
    Protein Accession:
    P48067
    Secondary Accessions:
    • A6NDH1
    • A6NII2
    • A6NNZ8
    • Q5TAB8
    • Q5TAB9
    • Q5TAC0

    Protein attributes for SLC6A9 Gene

    Size:
    706 amino acids
    Molecular mass:
    78260 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAB30784.1; Type=Frameshift; Positions=8; Evidence={ECO:0000305}; Sequence=AAB30785.1; Type=Frameshift; Positions=8; Evidence={ECO:0000305};

    Alternative splice isoforms for SLC6A9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC6A9 Gene

Post-translational modifications for SLC6A9 Gene

  • Glycosylation at isoforms=2, 3256
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for SLC6A9 Gene

Domains & Families for SLC6A9 Gene

Gene Families for SLC6A9 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Potential drug targets
  • Predicted membrane proteins
  • Predicted secreted proteins
  • Transporters

Suggested Antigen Peptide Sequences for SLC6A9 Gene

GenScript: Design optimal peptide antigens:
  • Transporter (B7Z589_HUMAN)
  • Transporter (B7Z9G8_HUMAN)
  • Transporter (E9PJ65_HUMAN)
  • Solute carrier family 6 member 9 (SC6A9_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P48067

UniProtKB/Swiss-Prot:

SC6A9_HUMAN :
  • Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
Family:
  • Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
genes like me logo Genes that share domains with SLC6A9: view

Function for SLC6A9 Gene

Molecular function for SLC6A9 Gene

UniProtKB/Swiss-Prot Function:
Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.
GENATLAS Biochemistry:
solute carrier family 6,member A9,neurotransmitter transporter,glycine

Phenotypes From GWAS Catalog for SLC6A9 Gene

Gene Ontology (GO) - Molecular Function for SLC6A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005283 amino acid:sodium symporter activity IEA --
GO:0005328 neurotransmitter:sodium symporter activity IEA --
GO:0015187 glycine transmembrane transporter activity IBA 21873635
GO:0015293 symporter activity IEA --
GO:0015375 glycine:sodium symporter activity TAS 8183239
genes like me logo Genes that share ontologies with SLC6A9: view
genes like me logo Genes that share phenotypes with SLC6A9: view

Human Phenotype Ontology for SLC6A9 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SLC6A9 Gene

MGI Knock Outs for SLC6A9:

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC6A9

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC6A9

Clone Products

  • Applied Biological Materials (abm): Clones for SLC6A9 - Now 50% OFF >
  • * SLC6A9 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * SLC6A9 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for SLC6A9 Gene

Localization for SLC6A9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC6A9 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SLC6A9 gene
Compartment Confidence
plasma membrane 5
nucleus 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SLC6A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS,IBA --
GO:0005887 integral component of plasma membrane TAS,IEA 8183239
GO:0014069 postsynaptic density IEA --
GO:0016020 membrane IEA,TAS 8183239
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SLC6A9: view

Pathways & Interactions for SLC6A9 Gene

genes like me logo Genes that share pathways with SLC6A9: view

Gene Ontology (GO) - Biological Process for SLC6A9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003333 amino acid transmembrane transport IEA --
GO:0006836 neurotransmitter transport IEA --
GO:0006865 amino acid transport IEA --
GO:0015816 glycine transport IEA --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with SLC6A9: view

No data available for SIGNOR curated interactions for SLC6A9 Gene

Drugs & Compounds for SLC6A9 Gene

(22) Drugs for SLC6A9 Gene - From: DrugBank, ApexBio, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Glycine Approved, Vet_approved Nutra Full agonist, Agonist, Target 352
Sarcosine Investigational Pharma GlyT1 inhibitor 0
Bitopertin Investigational Pharma Glycine reuptake inhibitor(GlyT1) 0
NFPS Pharma Inhibition, Inhibitor Selective non-transportable GlyT1 inhibitor 0
ALX 5407 hydrochloride Pharma GlyT1 inhibitor,selective non-transportable, Selective non-transportable GlyT1 inhibitor 0

(6) Additional Compounds for SLC6A9 Gene - From: IUPHAR, Novoseek, and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
NPTS
Inhibition, Inhibitor
Org 24598
Inhibition, Inhibitor
RG1678
Inhibition, Inhibitor
SB-733993
Inhibition, Inhibitor
sodium
  • Na(+)
  • Na+
  • SODIUM ion
7440-23-5

(5) Tocris Compounds for SLC6A9 Gene

Compound Action Cas Number
ALX 5407 hydrochloride Selective non-transportable GlyT1 inhibitor 200006-08-2
LY 2365109 hydrochloride Potent and selective GlyT1 inhibitor 868265-28-5
NFPS Selective non-transportable GlyT1 inhibitor 405225-21-0
Org 24598 lithium salt Selective GlyT1 inhibitor 722456-08-8
Sarcosine GlyT1 inhibitor 107-97-1

(7) ApexBio Compounds for SLC6A9 Gene

Compound Action Cas Number
ALX 5407 hydrochloride GlyT1 inhibitor,selective non-transportable 200006-08-2
Bitopertin Glycine reuptake inhibitor(GlyT1) 845614-11-1
Bitopertin (R enantiomer) Glycine reuptake inhibitor 845614-12-2
LY 2365109 hydrochloride 868265-28-5
NFPS 405225-21-0
Org 24598 lithium salt 722456-08-8
Sarcosine 107-97-1
genes like me logo Genes that share compounds with SLC6A9: view

Drug Products

Transcripts for SLC6A9 Gene

Unigene Clusters for SLC6A9 Gene

Solute carrier family 6 (neurotransmitter transporter, glycine), member 9:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC6A9

Clone Products

  • Applied Biological Materials (abm): Clones for SLC6A9 - Now 50% OFF >
  • * SLC6A9 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * SLC6A9 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for SLC6A9 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
SP1: - -
SP2: - - -
SP3: - - - - -
SP4: - - - - - - -
SP5: - - -
SP6: - - - -
SP7:

Relevant External Links for SLC6A9 Gene

GeneLoc Exon Structure for
SLC6A9
ECgene alternative splicing isoforms for
SLC6A9

Expression for SLC6A9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SLC6A9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC6A9 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x6.5) and Skin - Sun Exposed (Lower leg) (x4.0).

Protein differential expression in normal tissues from HIPED for SLC6A9 Gene

This gene is overexpressed in Retina (33.6) and Spinal cord (21.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SLC6A9 Gene



Protein tissue co-expression partners for SLC6A9 Gene

NURSA nuclear receptor signaling pathways regulating expression of SLC6A9 Gene:

SLC6A9

SOURCE GeneReport for Unigene cluster for SLC6A9 Gene:

Hs.442590

mRNA Expression by UniProt/SwissProt for SLC6A9 Gene:

P48067-SC6A9_HUMAN
Tissue specificity: Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain.

Evidence on tissue expression from TISSUES for SLC6A9 Gene

  • Nervous system(4.5)
genes like me logo Genes that share expression patterns with SLC6A9: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC6A9 Gene

Orthologs for SLC6A9 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC6A9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC6A9 35 34
  • 99.66 (n)
OneToOne
cow
(Bos Taurus)
Mammalia SLC6A9 35 34
  • 91.49 (n)
OneToOne
dog
(Canis familiaris)
Mammalia SLC6A9 35 34
  • 91.24 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLC6A9 35
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slc6a9 17 35 34
  • 90.64 (n)
rat
(Rattus norvegicus)
Mammalia Slc6a9 34
  • 90.48 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia SLC6A9 35
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves SLC6A9 35 34
  • 82.14 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SLC6A9 35
  • 83 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slc6a9 34
  • 72.35 (n)
zebrafish
(Danio rerio)
Actinopterygii slc6a9 35 34
  • 72.9 (n)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Ntl 34
  • 53.42 (n)
ine 36
  • 41 (a)
CG4476 36
  • 37 (a)
BG:DS03431.1 36
  • 37 (a)
CG3252 36
  • 37 (a)
CG1698 36
  • 36 (a)
CG7075 36
  • 35 (a)
CG8850 36
  • 34 (a)
CG5549 35 36
  • 25 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008467 34
  • 52 (n)
worm
(Caenorhabditis elegans)
Secernentea snf-3 36
  • 37 (a)
snf-9 36
  • 34 (a)
snf-4 36
  • 34 (a)
snf-5 36
  • 31 (a)
snf-6 36
  • 31 (a)
snf-12 36
  • 31 (a)
snf-2 36
  • 30 (a)
snf-1 36
  • 25 (a)
Species where no ortholog for SLC6A9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC6A9 Gene

ENSEMBL:
Gene Tree for SLC6A9 (if available)
TreeFam:
Gene Tree for SLC6A9 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SLC6A9: view image

Paralogs for SLC6A9 Gene

(21) SIMAP similar genes for SLC6A9 Gene using alignment to 7 proteins:

  • SC6A9_HUMAN
  • B7Z3A9_HUMAN
  • B7Z589_HUMAN
  • B7Z9G8_HUMAN
  • E9PJ65_HUMAN
  • E9PLM5_HUMAN
  • J3KPA5_HUMAN

Pseudogenes.org Pseudogenes for SLC6A9 Gene

genes like me logo Genes that share paralogs with SLC6A9: view

Variants for SLC6A9 Gene

Sequence variations from dbSNP and Humsavar for SLC6A9 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1057519313 pathogenic, Glycine encephalopathy with normal serum glycine, Glycine encephalopathy with normal serum glycine (GCENSG) [MIM:617301] 44,001,590(-) T/C coding_sequence_variant, missense_variant, non_coding_transcript_variant
rs1057519314 pathogenic, Glycine encephalopathy with normal serum glycine 44,000,805(-) G/A coding_sequence_variant, non_coding_transcript_variant, stop_gained
rs1057519315 pathogenic, Glycine encephalopathy with normal serum glycine 44,002,863(-) GACTTGAC/GAC coding_sequence_variant, frameshift, non_coding_transcript_variant
rs113184612 benign, Glycine encephalopathy with normal serum glycine 43,998,031(-) C/A/G/T downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant
rs193921002 uncertain-significance, Malignant tumor of prostate 44,008,366(-) C/T coding_sequence_variant, missense_variant, non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SLC6A9 Gene

Variant ID Type Subtype PubMed ID
nsv519538 CNV loss 19592680
nsv546142 CNV loss 21841781
nsv546143 CNV loss 21841781
nsv829704 CNV loss 17160897

Variation tolerance for SLC6A9 Gene

Residual Variation Intolerance Score: 8.58% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.05; 37.60% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SLC6A9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC6A9
Human Gene Mutation Database (HGMD)
SLC6A9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC6A9 Gene

Disorders for SLC6A9 Gene

MalaCards: The human disease database

(5) MalaCards diseases for SLC6A9 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

SC6A9_HUMAN
  • Glycine encephalopathy with normal serum glycine (GCENSG) [MIM:617301]: An autosomal recessive, severe metabolic disorder characterized by arthrogryposis multiplex congenita, joint hyperlaxity, lack of neonatal respiratory effort, axial hypotonia, hypertonia with pronounced clonus, and delayed psychomotor development. Some patients may have dysmorphic facial features and/or brain imaging abnormalities. Laboratory studies show increased CSF glycine and normal or only mildly increased serum glycine. Most patients die in infancy. {ECO:0000269 PubMed:27481395, ECO:0000269 PubMed:27773429}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for SLC6A9

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with SLC6A9: view

No data available for Genatlas for SLC6A9 Gene

Publications for SLC6A9 Gene

  1. The glycine transporter 1 gene (GLYT1) is associated with methamphetamine-use disorder. (PMID: 17582620) Morita Y … Kuroda S (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008) 3 23 45 58
  2. Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia. (PMID: 18638388) Deng X … Fukumaki Y (BMC psychiatry 2008) 3 23 45 58
  3. Association study of polymorphisms in glycine transporter with schizophrenia. (PMID: 16604304) Tsai SJ … Liou YJ (Journal of neural transmission (Vienna, Austria : 1996) 2006) 3 23 45 58
  4. Polymorphisms in glycine transporter with schizophrenia. (PMID: 16841561) Tsai SJ … Liou YJ (Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 2006) 3 23 45 58
  5. Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes. (PMID: 8183239) Kim KM … Giros B (Molecular pharmacology 1994) 2 3 4 58

Products for SLC6A9 Gene

Sources for SLC6A9 Gene

Content
Loading form....