Aliases for SLC6A6 Gene
External Ids for SLC6A6 Gene
Previous GeneCards Identifiers for SLC6A6 Gene
This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
GeneCards Summary for SLC6A6 Gene
SLC6A6 (Solute Carrier Family 6 Member 6) is a Protein Coding gene. Diseases associated with SLC6A6 include Cerebral Creatine Deficiency Syndrome 2 and Cerebral Creatine Deficiency Syndrome. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and NRF2 pathway. Gene Ontology (GO) annotations related to this gene include neurotransmitter:sodium symporter activity and taurine transmembrane transporter activity. An important paralog of this gene is SLC6A13.
UniProtKB/Swiss-Prot for SLC6A6 Gene
Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.