Aliases for SLC6A20 Gene
External Ids for SLC6A20 Gene
Previous GeneCards Identifiers for SLC6A20 Gene
Transport of small hydrophilic substances across cell membranes is mediated by substrate-specific transporter proteins which have been classified into several families of related genes. The protein encoded by this gene is a member of the subgroup of transporter with unidentified substrates within the Na+ and Cl- coupled transporter family. This gene is expressed in kidney, and its alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008]
GeneCards Summary for SLC6A20 Gene
SLC6A20 (Solute Carrier Family 6 Member 20) is a Protein Coding gene. Diseases associated with SLC6A20 include Iminoglycinuria and Hyperglycinuria. Among its related pathways are NRF2 pathway and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include amino acid transmembrane transporter activity and neurotransmitter:sodium symporter activity. An important paralog of this gene is SLC6A18.
UniProtKB/Swiss-Prot Summary for SLC6A20 Gene
Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids. Involved in the transport of glycine.