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SLC45A3 (Solute Carrier Family 45 Member 3) is a Protein Coding gene. Diseases associated with SLC45A3 include Villous Adenoma and Prostate Small Cell Carcinoma. Among its related pathways are Transcriptional misregulation in cancer and Hexose transport. An important paralog of this gene is SLC45A4.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008506 | sucrose:proton symporter activity | IEA,ISS | -- |
GO:0051119 | sugar transmembrane transporter activity | TAS | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | TAS | -- |
GO:0016020 | membrane | IBA | 21873635 |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Hexose transport |
.85
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2 | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||
3 | MicroRNAs in cancer | ||
4 | Transcriptional misregulation in cancer | ||
5 | Metabolism |
.40
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GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0008645 | hexose transmembrane transport | TAS | -- |
GO:0010907 | positive regulation of glucose metabolic process | IEA,ISS | -- |
GO:0015770 | sucrose transport | IEA,ISS | -- |
GO:0045723 | positive regulation of fatty acid biosynthetic process | IEA,ISS | -- |
GO:0048713 | regulation of oligodendrocyte differentiation | IEA,ISS | -- |
ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||
SP2: | - |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | SLC45A3 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | SLC45A3 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Slc45a3 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Slc45a3 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | SLC45A3 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | SLC45A3 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | SLC45A3 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | SLC45A3 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | slc45a3 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | MGC68967 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | slc45a3 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | CG40467 31 |
|
OneToMany | |
Slc45-1 31 |
|
OneToMany | |||
CG41343 31 |
|
OneToMany |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2721929 | CNV | deletion | 23290073 |
esv2721940 | CNV | deletion | 23290073 |
nsv1126227 | CNV | deletion | 24896259 |
nsv4188 | CNV | insertion | 18451855 |
Disorder | Aliases | PubMed IDs |
---|---|---|
villous adenoma |
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|
prostate small cell carcinoma |
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|
prostate cancer |
|
|
prostatic acinar adenocarcinoma |
|
|
radiation cystitis |
|
|