Aliases for SLC43A1 Gene
External Ids for SLC43A1 Gene
Previous HGNC Symbols for SLC43A1 Gene
Previous GeneCards Identifiers for SLC43A1 Gene
SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SLC43A1 Gene
SLC43A1 (Solute Carrier Family 43 Member 1) is a Protein Coding gene. Diseases associated with SLC43A1 include Prostate Cancer and Seminoma. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Amino acid transport across the plasma membrane. Gene Ontology (GO) annotations related to this gene include neutral amino acid transmembrane transporter activity and L-amino acid transmembrane transporter activity. An important paralog of this gene is SLC43A2.
UniProtKB/Swiss-Prot Summary for SLC43A1 Gene
Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.