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Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied... See more...
Aliases for SLC39A6 Gene
Aliases for SLC39A6 Gene
External Ids for SLC39A6 Gene
- HGNC: 18607
- Entrez Gene: 25800
- Ensembl: ENSG00000141424
- OMIM: 608731
- UniProtKB: Q13433
Previous GeneCards Identifiers for SLC39A6 Gene
- GC18M033576
- GC18M031941
- GC18M031940
- GC18M031943
- GC18M033688
- GC18M030547
Summaries for SLC39A6 Gene
-
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SLC39A6 Gene
SLC39A6 (Solute Carrier Family 39 Member 6) is a Protein Coding gene. Diseases associated with SLC39A6 include Acrodermatitis Enteropathica, Zinc-Deficiency Type and Breast Cancer. Among its related pathways are Metal ion SLC transporters and NRF2 pathway. Gene Ontology (GO) annotations related to this gene include metal ion transmembrane transporter activity and zinc ion transmembrane transporter activity. An important paralog of this gene is SLC39A10.
UniProtKB/Swiss-Prot Summary for SLC39A6 Gene
-
May act as a zinc-influx transporter.
Additional gene information for SLC39A6 Gene
- Monarch Initiative
- Search for SLC39A6 at DataMed
- Search for SLC39A6 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLC39A6 Gene
Genomics for SLC39A6 Gene
GeneHancer (GH) Regulatory Elements for SLC39A6 Gene
Promoters and enhancers for SLC39A6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around SLC39A6 on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SLC39A6
- Top Transcription factor binding sites by QIAGEN in the SLC39A6 gene promoter:
-
- CP2
- FOXO3
- FOXO3a
- FOXO3b
- FOXO4
- GATA-1
- POU2F1
- POU2F1a
- Roaz
- STAT3
Genomic Locations for SLC39A6 Gene
Genomic Locations for SLC39A6 Gene
- chr18:36,108,531-36,129,814
- (GRCh38/hg38)
- Size:
- 21,284 bases
- Orientation:
- Minus strand
- chr18:33,688,494-33,709,357
- (GRCh37/hg19)
- Size:
- 20,864 bases
- Orientation:
- Minus strand
Genomic View for SLC39A6 Gene
Genes around SLC39A6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18q12.2 by HGNC
- 18q12.2 by Entrez Gene
- 18q12.2 by Ensembl
SLC39A6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for SLC39A6 Gene
Proteins for SLC39A6 Gene
-
Protein details for SLC39A6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q13433-S39A6_HUMAN
- Recommended name:
- Zinc transporter ZIP6
- Protein Accession:
- Q13433
- B4DR49
- B4E224
- Q8IXR3
- Q96HP5
Protein attributes for SLC39A6 Gene
- Size:
- 755 amino acids
- Molecular mass:
- 85047 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAG61161.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for SLC39A6 Gene
Post-translational modifications for SLC39A6 Gene
Other Protein References for SLC39A6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ LIV-1/ZIP6 Antibody
- Creative Diagnostics Rabbit Anti-Human SLC39A6 Polyclonal antibody
- Creative Biolabs Human Anti-Human slc39a6 Antibody
- Novus Biologicals Antibodies for SLC39A6
- Invitrogen Antibodies for SLC39A6 (AFLGC-SLC39A6)
-
Custom Antibody ServicesProSci Antibodies for SLC39A6
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for SLC39A6
- Origene Custom Protein Services for SLC39A6
- Novus Biologicals proteins for SLC39A6
Assay Products
- Aviva Systems Biology SLC39A6 ELISA Kit (Human) (OKCD00939)
- antibodies-online: Show 5 available SLC39A6 Elisa Kits ranked by validation data
- Compare Top SLC39A6 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for SLC39A6 Gene
Domains & Families for SLC39A6 Gene
Gene Families for SLC39A6 Gene
- HGNC:
- IUPHAR :
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Transporters
Suggested Antigen Peptide Sequences for SLC39A6 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ50261, highly similar to Zinc transporter SLC39A6 (B4DWH6_HUMAN)
- Zrt- and Irt-like protein 6 (S39A6_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q13433- Family:
-
- Belongs to the ZIP transporter (TC 2.A.5) family.
Function for SLC39A6 Gene
Molecular function for SLC39A6 Gene
- UniProtKB/Swiss-Prot Function:
- May act as a zinc-influx transporter.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated by estrogen in breast cancer cells lines.
Phenotypes From GWAS Catalog for SLC39A6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005385 | zinc ion transmembrane transporter activity | IDA | 15642354 |
| GO:0046873 | metal ion transmembrane transporter activity | IEA | -- |
Phenotypes for SLC39A6 Gene
- MGI mutant phenotypes for SLC39A6:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for SLC39A6:
Animal Models for SLC39A6 Gene
- MGI Knock Outs for SLC39A6:
-
- Slc39a6 Slc39a6<tm1Tfk>
Animal Model Products
-
Taconic Biosciences Mouse Models for SLC39A6
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SLC39A6 - Select products 50% OFF >
- * SLC39A6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SLC39A6 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for SLC39A6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SLC39A6
- genomics-online: gRNA clones - Search for available SLC39A6 gRNA products
- Overview of 103 available SLC39A6 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SLC39A6
miRNA for SLC39A6 Gene
- miRTarBase miRNAs that target SLC39A6
-
- hsa-mir-32-5p (MIRT028339)
- hsa-mir-26b-5p (MIRT029131)
- hsa-mir-3163 (MIRT080040)
- hsa-mir-323a-5p (MIRT439602)
- hsa-mir-539-5p (MIRT439603)
- hsa-mir-101-3p (MIRT545416)
- hsa-mir-126-3p (MIRT545417)
- hsa-mir-548v (MIRT545418)
- hsa-mir-139-5p (MIRT545419)
- hsa-mir-135b-5p (MIRT545420)
- hsa-mir-135a-5p (MIRT545421)
- hsa-mir-889-5p (MIRT545422)
- hsa-mir-410-3p (MIRT545423)
- hsa-mir-144-3p (MIRT545424)
- hsa-mir-7849-3p (MIRT545425)
- hsa-mir-92b-3p (MIRT726527)
- hsa-mir-92a-3p (MIRT726528)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SLC39A6
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC39A6
- genomics-online: shRNA clones - Search for available SLC39A6 shRNA products
- Overview of 103 available SLC39A6 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for SLC39A6 - Select products 50% OFF >
- * SLC39A6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SLC39A6 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for SLC39A6
- Addgene plasmids for SLC39A6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SLC39A6
Cell Line Products
-
Horizon Cell Lines for SLC39A6
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SLC39A6 Gene
Localization for SLC39A6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for SLC39A6 Gene
- Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| endoplasmic reticulum | 3 |
| extracellular | 2 |
| nucleus | 2 |
| cytosol | 2 |
| lysosome | 2 |
| golgi apparatus | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endosome | 1 |
- Plasma membrane (3)
- Cytosol (1)
- Nucleoplasm (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005623 | cell | IEA | -- |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | IDA | 15642354 |
| GO:0009986 | cell surface | HDA | 19581412 |
Pathways & Interactions for SLC39A6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metal ion SLC transporters |
.38
|
|
| 2 | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||
| 3 | NRF2 pathway | ||
Pathways by source for SLC39A6 Gene
2 BioSystems pathways for SLC39A6 Gene
Interacting Proteins for SLC39A6 Gene
GPS-Prot Interaction Network for SLC39A6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006811 | ion transport | IEA | -- |
| GO:0006829 | zinc ion transport | IEA | -- |
| GO:0006882 | cellular zinc ion homeostasis | IDA | 15642354 |
| GO:0030001 | metal ion transport | IEA | -- |
| GO:0055085 | transmembrane transport | IEA | -- |
No data available for SIGNOR curated interactions for SLC39A6 Gene
Transcripts for SLC39A6 Gene
mRNA/cDNA for SLC39A6 Gene
- 2 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000269187 3566 bps (ENST00000269187.10)
- ENST00000440549 1657 bps (ENST00000440549.6)
- ENST00000586829 823 bps (ENST00000586829.1)
- ENST00000590986 3003 bps (ENST00000590986.5)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for SLC39A6 - Select products 50% OFF >
- * SLC39A6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * SLC39A6 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for SLC39A6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SLC39A6
- genomics-online: gRNA clones - Search for available SLC39A6 gRNA products
- Overview of 103 available SLC39A6 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for SLC39A6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for SLC39A6
- Browse OriGene Inhibitory RNA Products For SLC39A6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC39A6
- genomics-online: shRNA clones - Search for available SLC39A6 shRNA products
- Overview of 103 available SLC39A6 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for SLC39A6 - Select products 50% OFF >
- * SLC39A6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * SLC39A6 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for SLC39A6
- Addgene plasmids for SLC39A6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for SLC39A6
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||
| SP5: | - |
Relevant External Links for SLC39A6 Gene
- GeneLoc Exon Structure for
- SLC39A6
Expression for SLC39A6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
- Brain (Nervous System)
- Intestine (Gastrointestinal Tract)
- Pancreas (Endocrine System)
- Ovary (Reproductive System)
-
Uterus (Reproductive System)
-
Prostate (Endocrine System)
This gene is overexpressed in Fetal Brain (33.9) and Frontal cortex (25.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for SLC39A6 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLC39A6
SOURCE GeneReport for Unigene cluster for SLC39A6 Gene:
Hs.79136mRNA Expression by UniProt/SwissProt for SLC39A6 Gene:
Q13433-S39A6_HUMAN
Tissue specificity:
Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma.
Evidence on tissue expression from TISSUES for SLC39A6 Gene
- Eye(4.2)
- Nervous system(3)
Primer Products
-
OriGene qPCR primer pairs for SLC39A6
-
OriGene qPCR primer pairs and template standards for SLC39A6
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC39A6 Gene
Orthologs for SLC39A6 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | SLC39A6 31 30 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | SLC39A6 31 30 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | SLC39A6 31 30 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Slc39a6 30 |
|
||
| mouse (Mus musculus) |
Mammalia | Slc39a6 17 31 30 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | SLC39A6 31 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | SLC39A6 31 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | SLC39A6 31 30 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | SLC39A6 31 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100487349 30 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | slc39a6 31 30 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | foi 31 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for SLC39A6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for SLC39A6 Gene
- ENSEMBL:
- Gene Tree for SLC39A6 (if available)
- TreeFam:
- Gene Tree for SLC39A6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for SLC39A6: view image
Paralogs for SLC39A6 Gene
Variants for SLC39A6 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SLC39A6 Gene
| SNP ID | Clinical significance and condition | Chr 18 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1789528 | - | p.Glu119Asp |
Residual Variation Intolerance Score:
9.02% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.42;
27.87% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for SLC39A6 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC39A6 Gene
Disorders for SLC39A6 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| acrodermatitis enteropathica, zinc-deficiency type |
|
|
| breast cancer |
|
|
Search SLC39A6 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for SLC39A6
No data available for UniProtKB/Swiss-Prot and Genatlas for SLC39A6 Gene
Publications for SLC39A6 Gene
- Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters. (PMID: 12839489) Taylor KM … Nicholson RI (The Biochemical journal 2003) 2 3 4 23 54
- The LZT proteins; the LIV-1 subfamily of zinc transporters. (PMID: 12659941) Taylor KM … Nicholson RI (Biochimica et biophysica acta 2003) 2 3 23 54
- Concordant correlation of LIV-1 and E-cadherin expression in human breast cancer cell MCF-7. (PMID: 18330719) Shen H … Guo J (Molecular biology reports 2009) 3 23 54
- LIV-1 suppression inhibits HeLa cell invasion by targeting ERK1/2-Snail/Slug pathway. (PMID: 17825787) Zhao L … Li X (Biochemical and biophysical research communications 2007) 3 23 54
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
ExternalLinks
Products for SLC39A6 Gene
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- Novus Biologicals proteins for SLC39A6
- Browse Antibodies
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- Taconic Biosciences Mouse Models for SLC39A6
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for SLC39A6 (AFLGC-SLC39A6)
- Addgene plasmids for SLC39A6
- antibodies-online: Show 18 available SLC39A6 Antibodies ranked by validation data
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- Quality Products:
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- Santa Cruz Biotechnology (SCBT) CRISPR for SLC39A6
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- Search for SLC39A6 Proteins at ProSci
- Horizon Cell Lines for SLC39A6
- genomics-online: cdna clones - Search for available SLC39A6 CDNA products
- Overview of 103 available SLC39A6 gene related products
- orf clones - Search for available SLC39A6 ORF products
- Overview of 103 available SLC39A6 gene related products
- genomics-online: gRNA clones - Search for available SLC39A6 gRNA products
- Overview of 103 available SLC39A6 gene related products
- genomics-online: primer clones - Search for available SLC39A6 Primer products
- Overview of 103 available SLC39A6 gene related products
- genomics-online: shRNA clones - Search for available SLC39A6 shRNA products
- Overview of 103 available SLC39A6 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for SLC39A6
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for SLC39A6
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Sources for SLC39A6 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
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