Aliases for SLC39A6 Gene
External Ids for SLC39A6 Gene
Previous GeneCards Identifiers for SLC39A6 Gene
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SLC39A6 Gene
SLC39A6 (Solute Carrier Family 39 Member 6) is a Protein Coding gene. Diseases associated with SLC39A6 include Acrodermatitis Enteropathica, Zinc-Deficiency Type and Breast Cancer. Among its related pathways are Metal ion SLC transporters and NRF2 pathway. Gene Ontology (GO) annotations related to this gene include metal ion transmembrane transporter activity and zinc ion transmembrane transporter activity. An important paralog of this gene is SLC39A10.
UniProtKB/Swiss-Prot Summary for SLC39A6 Gene
May act as a zinc-influx transporter.