Aliases for SLC39A12 Gene
External Ids for SLC39A12 Gene
Previous GeneCards Identifiers for SLC39A12 Gene
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Aug 2008]
GeneCards Summary for SLC39A12 Gene
SLC39A12 (Solute Carrier Family 39 Member 12) is a Protein Coding gene. Diseases associated with SLC39A12 include Acrodermatitis Enteropathica, Zinc-Deficiency Type. Among its related pathways are NRF2 pathway and Metal ion SLC transporters. Gene Ontology (GO) annotations related to this gene include metal ion transmembrane transporter activity and zinc ion transmembrane transporter activity. An important paralog of this gene is SLC39A4.
UniProtKB/Swiss-Prot Summary for SLC39A12 Gene
Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia.