Aliases for SLC39A1 Gene
External Ids for SLC39A1 Gene
Previous HGNC Symbols for SLC39A1 Gene
Previous GeneCards Identifiers for SLC39A1 Gene
This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
GeneCards Summary for SLC39A1 Gene
SLC39A1 (Solute Carrier Family 39 Member 1) is a Protein Coding gene. Diseases associated with SLC39A1 include Prostate Cancer and Alzheimer Disease. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Metal ion SLC transporters. Gene Ontology (GO) annotations related to this gene include receptor binding and zinc ion transmembrane transporter activity. An important paralog of this gene is SLC39A2.
UniProtKB/Swiss-Prot for SLC39A1 Gene
Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.