Aliases for SLC37A1 Gene
External Ids for SLC37A1 Gene
Previous GeneCards Identifiers for SLC37A1 Gene
The protein encoded by this gene localizes to the endoplasmic reticulum (ER) membrane. This protein translocates glucose-6-phosphate from the cytoplasm into the lumen of the ER for hydrolysis into glucose by another ER membrane protein. This gene is a member of the solute carrier 37 gene family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for SLC37A1 Gene
SLC37A1 (Solute Carrier Family 37 Member 1) is a Protein Coding gene. Diseases associated with SLC37A1 include Glycerol Kinase Deficiency and Deafness, Autosomal Recessive 8. Gene Ontology (GO) annotations related to this gene include transporter activity. An important paralog of this gene is SLC37A2.
UniProtKB/Swiss-Prot Summary for SLC37A1 Gene
Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.