Aliases for SLC36A1 Gene
External Ids for SLC36A1 Gene
Previous GeneCards Identifiers for SLC36A1 Gene
This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
GeneCards Summary for SLC36A1 Gene
SLC36A1 (Solute Carrier Family 36 Member 1) is a Protein Coding gene. Diseases associated with SLC36A1 include Spinocerebellar Ataxia 45 and Iminoglycinuria. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include symporter activity and L-alanine transmembrane transporter activity. An important paralog of this gene is SLC36A2.
UniProtKB/Swiss-Prot Summary for SLC36A1 Gene
Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Besides small apolar L-amino acids, it also recognizes their D-enantiomers and selected amino acid derivatives such as gamma-aminobutyric acid (By similarity).