Aliases for SLC35C2 Gene
External Ids for SLC35C2 Gene
Previous HGNC Symbols for SLC35C2 Gene
Previous GeneCards Identifiers for SLC35C2 Gene
This gene encodes a member of the triose-phosphate transporter protein family. This gene is regulated by oxygen tension, is induced in hypoxic trophoblast cells, and is overexpressed in ovarian cancer. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]
GeneCards Summary for SLC35C2 Gene
SLC35C2 (Solute Carrier Family 35 Member C2) is a Protein Coding gene. Diseases associated with SLC35C2 include Dicarboxylic Aminoaciduria and Hydranencephaly. An important paralog of this gene is SLC35E2B.
UniProtKB/Swiss-Prot Summary for SLC35C2 Gene
May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells.