Aliases for SLC35B3 Gene
External Ids for SLC35B3 Gene
Previous HGNC Symbols for SLC35B3 Gene
Previous GeneCards Identifiers for SLC35B3 Gene
This gene is a member of the solute carrier family. The encoded protein is involved in the transport of 3-prime phosphoadenosine 5-prime phosphosulfate (PAPS) from the nucleus or the cytosol to the Golgi lumen. This gene has been reported to be expressed preferentially in the human colon tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for SLC35B3 Gene
SLC35B3 (Solute Carrier Family 35 Member B3) is a Protein Coding gene. Diseases associated with SLC35B3 include Orofacial Cleft 1 and Schneckenbecken Dysplasia. Among its related pathways are Cytochrome P450 - arranged by substrate type and Metabolism. An important paralog of this gene is SLC35B1.
UniProtKB/Swiss-Prot Summary for SLC35B3 Gene
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon.