SLC34A1 Gene (Protein Coding)

Solute Carrier Family 34 Member 1

GC05P177380
GIFtS:
45
This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] See more...

Aliases for SLC34A1 Gene

Aliases for SLC34A1 Gene

  • Solute Carrier Family 34 Member 1 2 3 4 5
  • Solute Carrier Family 34 (Type II Sodium/Phosphate Cotransporter), Member 1 2 3
  • Solute Carrier Family 17 (Sodium Phosphate), Member 2 2 3
  • Solute Carrier Family 34 (Sodium Phosphate), Member 1 2 3
  • Sodium-Dependent Phosphate Transport Protein 2A 3 4
  • Na(+)-Dependent Phosphate Cotransporter 2A 3 4
  • Sodium-Phosphate Transport Protein 2A 3 4
  • Na+-Phosphate Cotransporter Type II 2 3
  • Sodium/Phosphate Cotransporter 2A 3 4
  • Sodium/Phosphate Co-Transporter 2 3
  • Na(+)/Pi Cotransporter 2A 3 4
  • SLC17A2 3 4
  • NaPi-2a 3 4
  • NAPI-3 2 3
  • NPTIIa 2 3
  • SLC11 2 3
  • NPT2 3 4
  • Renal Sodium-Dependent Phosphate Transporter 3
  • NPHLOP1 3
  • SLC34A1 5
  • HCINF2 3
  • NaPi-3 4
  • FRTS2 3

External Ids for SLC34A1 Gene

Previous HGNC Symbols for SLC34A1 Gene

  • NPT2
  • SLC17A2

Previous GeneCards Identifiers for SLC34A1 Gene

  • GC05P177184
  • GC05P177653
  • GC05P176747
  • GC05P176792
  • GC05P176744
  • GC05P176812
  • GC05P171732

Summaries for SLC34A1 Gene

Entrez Gene Summary for SLC34A1 Gene

  • This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]

GeneCards Summary for SLC34A1 Gene

SLC34A1 (Solute Carrier Family 34 Member 1) is a Protein Coding gene. Diseases associated with SLC34A1 include Hypercalcemia, Infantile, 2 and Nephrolithiasis/Osteoporosis, Hypophosphatemic, 1. Among its related pathways are Surfactant metabolism and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and PDZ domain binding. An important paralog of this gene is SLC34A2.

UniProtKB/Swiss-Prot Summary for SLC34A1 Gene

  • Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx.

Additional gene information for SLC34A1 Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for SLC34A1 Gene

Genomics for SLC34A1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for SLC34A1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around SLC34A1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for SLC34A1

Top Transcription factor binding sites by QIAGEN in the SLC34A1 gene promoter:
  • AP-1
  • c-Fos
  • c-Jun
  • FosB
  • Fra-1
  • JunB
  • JunD
  • p53
  • STAT5A
  • YY1

Genomic Locations for SLC34A1 Gene

Latest Assembly
chr5:177,379,235-177,412,021
(GRCh38/hg38)
Size:
32,787 bases
Orientation:
Plus strand

Previous Assembly
chr5:176,811,435-176,825,849
(GRCh37/hg19 by Entrez Gene)
Size:
14,415 bases
Orientation:
Plus strand

chr5:176,806,236-176,825,849
(GRCh37/hg19 by Ensembl)
Size:
19,614 bases
Orientation:
Plus strand

Genomic View for SLC34A1 Gene

Genes around SLC34A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC34A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC34A1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for SLC34A1 Gene

Proteins for SLC34A1 Gene

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  1. Antibodies for research
  2. Protein products for research
  3. Assay products for research

  • Protein details for SLC34A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q06495-NPT2A_HUMAN
    Recommended name:
    Sodium-dependent phosphate transport protein 2A
    Protein Accession:
    Q06495
    Secondary Accessions:
    • B4DPE3

    Protein attributes for SLC34A1 Gene

    Size:
    639 amino acids
    Molecular mass:
    68937 Da
    Quaternary structure:
    • Interacts via its C-terminal region with PDZK2 (By similarity). Interacts with SLC9A3R1 (PubMed:22506049).

    Alternative splice isoforms for SLC34A1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC34A1 Gene

Protein Expression for SLC34A1 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for SLC34A1 Gene

  • Glycosylation at Asn298, Asn323, and Asn330
  • Modification sites at PhosphoSitePlus

Other Protein References for SLC34A1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SLC34A1 Gene

Domains & Families for SLC34A1 Gene

Gene Families for SLC34A1 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Disease related genes
  • Plasma proteins
  • Potential drug targets
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters

Protein Domains for SLC34A1 Gene

InterPro:
Blocks:
  • Na+/Pi-cotransporter

Suggested Antigen Peptide Sequences for SLC34A1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ60763, highly similar to Sodium-dependent phosphate transport protein 2A (B4DPE3_HUMAN)
  • Solute carrier family 34 member 1 (NPT2A_HUMAN)
  • Solute carrier family 34 (Sodium phosphate), member 1, isoform CRA_c (Q05BP0_HUMAN)
  • Na+-phosphate cotransporter type II (Q6LCI0_HUMAN)
  • Na+-phosphate cotransporter type II (Q6LCI1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q06495

UniProtKB/Swiss-Prot:

NPT2A_HUMAN :
  • Belongs to the SLC34A transporter family.
Family:
  • Belongs to the SLC34A transporter family.
genes like me logo Genes that share domains with SLC34A1: view

Function for SLC34A1 Gene

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  6. Cell Lines for research

Molecular function for SLC34A1 Gene

UniProtKB/Swiss-Prot Function:
Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx.
GENATLAS Biochemistry:
solute carrier family 34 (sodium/phosphate cotransport) member 1,expressed in kidney

Phenotypes From GWAS Catalog for SLC34A1 Gene

Gene Ontology (GO) - Molecular Function for SLC34A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005436 sodium:phosphate symporter activity IBA,IMP 26047794
GO:0005515 protein binding IPI 17895247
GO:0015293 symporter activity IEA --
GO:0030165 PDZ domain binding IEA --
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with SLC34A1: view
genes like me logo Genes that share phenotypes with SLC34A1: view

Human Phenotype Ontology for SLC34A1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SLC34A1 Gene

MGI Knock Outs for SLC34A1:

Animal Models for research

miRNA for SLC34A1 Gene

miRTarBase miRNAs that target SLC34A1

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC34A1

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for SLC34A1 Gene

Localization for SLC34A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC34A1 Gene

Apical cell membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SLC34A1 gene
Compartment Confidence
plasma membrane 5
cytoskeleton 4
nucleus 4
cytosol 4
endosome 3
extracellular 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (3)
  • Cytosol (1)
  • Mitotic spindle (1)
  • Nuclear speckles (1)
  • Nucleoplasm (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SLC34A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0005768 endosome IEA --
GO:0005829 cytosol IDA --
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane NAS 8327470
genes like me logo Genes that share ontologies with SLC34A1: view

Pathways & Interactions for SLC34A1 Gene

genes like me logo Genes that share pathways with SLC34A1: view

Gene Ontology (GO) - Biological Process for SLC34A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001503 ossification IEA --
GO:0001822 kidney development IEA --
GO:0006811 ion transport IEA --
GO:0006814 sodium ion transport IEA --
GO:0006817 phosphate ion transport IDA 8327470
genes like me logo Genes that share ontologies with SLC34A1: view

No data available for SIGNOR curated interactions for SLC34A1 Gene

Drugs & Compounds for SLC34A1 Gene

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(10) Drugs for SLC34A1 Gene - From: DrugBank and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Calcium Phosphate Approved Pharma Transporter, substrate 0
Calcium phosphate dihydrate Approved Pharma Transporter 0
Sodium phosphate, dibasic Approved Pharma Transporter 0
Sodium phosphate, monobasic Approved Pharma Transporter, substrate 0
Sodium phosphate, monobasic, unspecified form Approved Pharma Transporter 0

(3) Additional Compounds for SLC34A1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with SLC34A1: view

Transcripts for SLC34A1 Gene

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mRNA/cDNA for SLC34A1 Gene

2 REFSEQ mRNAs :
10 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for SLC34A1

Alternative Splicing Database (ASD) splice patterns (SP) for SLC34A1 Gene

No ASD Table

Relevant External Links for SLC34A1 Gene

GeneLoc Exon Structure for
SLC34A1

Expression for SLC34A1 Gene

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  1. Primer products for research
  2. Gene Expression Assays for research

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SLC34A1 Gene

mRNA expression in normal human tissues for SLC34A1 Gene
mRNA expression by GTEx for SLC34A1 GenemRNA expression by BioGPS for SLC34A1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SLC34A1 Gene

This gene is overexpressed in Kidney - Cortex (x51.1).

Protein differential expression in normal tissues from HIPED for SLC34A1 Gene

This gene is overexpressed in Brain (38.2) and Urine (30.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SLC34A1 Gene



Protein tissue co-expression partners for SLC34A1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for SLC34A1

SOURCE GeneReport for Unigene cluster for SLC34A1 Gene:

Hs.936

mRNA Expression by UniProt/SwissProt for SLC34A1 Gene:

Q06495-NPT2A_HUMAN
Tissue specificity: Kidney and lung.

Evidence on tissue expression from TISSUES for SLC34A1 Gene

  • Kidney(4.8)

Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC34A1 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Regions:
Head and neck:
  • brain
  • ear
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • neck
  • skull
  • tooth
Thorax:
  • chest wall
  • clavicle
  • diaphragm
  • heart
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • duodenum
  • intestine
  • kidney
  • large intestine
  • pancreas
  • small intestine
  • stomach
Pelvis:
  • pelvis
  • rectum
  • ureter
  • urinary bladder
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • coagulation system
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • spinal column
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with SLC34A1: view

Primer products for research

Orthologs for SLC34A1 Gene

This gene was present in the common ancestor of animals.

Orthologs for SLC34A1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia SLC34A1 29 30
  • 99.37 (n)
 OneToOne
Dog
(Canis familiaris)
 Mammalia SLC34A1 29 30
  • 88.63 (n)
 OneToOne
Cow
(Bos Taurus)
 Mammalia SLC34A1 29 30
  • 88.21 (n)
 OneToOne
Rat
(Rattus norvegicus)
 Mammalia Slc34a1 29
  • 86.92 (n)
Mouse
(Mus musculus)
 Mammalia Slc34a1 29 16 30
  • 86.24 (n)
 OneToOne
Oppossum
(Monodelphis domestica)
 Mammalia SLC34A1 30
  • 79 (a)
 OneToOne
Platypus
(Ornithorhynchus anatinus)
 Mammalia SLC34A1 30
  • 79 (a)
 OneToOne
Chicken
(Gallus gallus)
 Aves SLC34A1 29 30
  • 77.08 (n)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia SLC34A1 30
  • 64 (a)
 OneToOne
Zebrafish
(Danio rerio)
 Actinopterygii slc34a1a 29 30
  • 71.99 (n)
 OneToMany
slc34a1b 30
  • 69 (a)
 OneToMany
Worm
(Caenorhabditis elegans)
 Secernentea ZK563.2 29 30 31
  • 43.11 (n)
 OneToMany
Sea Squirt
(Ciona savignyi)
 Ascidiacea -- 30
  • 49 (a)
 ManyToMany
-- 30
  • 47 (a)
 ManyToMany
-- 30
  • 46 (a)
 ManyToMany
-- 30
  • 41 (a)
 ManyToMany
Species where no ortholog for SLC34A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)

Evolution for SLC34A1 Gene

ENSEMBL:
Gene Tree for SLC34A1 (if available)
TreeFam:
Gene Tree for SLC34A1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for SLC34A1: view image
Alliance of Genome Resources:
Additional Orthologs for SLC34A1

Paralogs for SLC34A1 Gene

Paralogs for SLC34A1 Gene

(3) SIMAP similar genes for SLC34A1 Gene using alignment to 5 proteins:

  • NPT2A_HUMAN
  • D6RCE5_HUMAN
  • Q05BP0_HUMAN
  • Q7Z725_HUMAN
  • Q86VN6_HUMAN
genes like me logo Genes that share paralogs with SLC34A1: view

Variants for SLC34A1 Gene

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Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for SLC34A1 Gene

SNP ID Clinical significance and condition Chr 05 pos Variation AA Info Type
1016508 Uncertain Significance: not provided 177,388,002(+) C/T
NM_003052.5(SLC34A1):c.653C>T (p.Ala218Val) 		MISSENSE
1018684 Uncertain Significance: not provided 177,387,854(+) G/T
NM_003052.5(SLC34A1):c.625G>T (p.Asp209Tyr) 		MISSENSE
1020657 Uncertain Significance: not provided 177,394,108(+) T/C
NM_003052.5(SLC34A1):c.1087T>C (p.Cys363Arg) 		MISSENSE
1028069 Likely Pathogenic: Hypercalcemia, infantile, 2 177,386,568(+) T/C
NM_003052.5(SLC34A1):c.532+2T>C 		SPLICE_DONOR
1036898 Uncertain Significance: not provided 177,402,561(+) CG/C
NM_000505.4(F12):c.1668del (p.Asp557fs) 		FRAMESHIFT

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for SLC34A1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for SLC34A1 Gene

Variant ID Type Subtype PubMed ID
dgv10184n54 CNV loss 21841781
dgv10185n54 CNV loss 21841781
dgv373e215 CNV deletion 23714750
dgv733n27 CNV loss 19166990
esv1007597 CNV deletion 20482838
esv2675618 CNV deletion 23128226
esv2731189 CNV deletion 23290073
esv2731190 CNV deletion 23290073
esv4214 CNV loss 18987735
nsv1074891 CNV deletion 25765185
nsv1148657 CNV deletion 26484159
nsv1161311 CNV duplication 26073780
nsv1161312 CNV deletion 26073780
nsv1161313 CNV duplication 26073780
nsv471057 CNV loss 18288195
nsv509103 CNV insertion 20534489
nsv600364 CNV loss 21841781

Variation tolerance for SLC34A1 Gene

Residual Variation Intolerance Score: 38.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.68; 57.18% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SLC34A1 Gene

Human Gene Mutation Database (HGMD)
SLC34A1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC34A1
Leiden Open Variation Database (LOVD)
SLC34A1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC34A1 Gene

Disorders for SLC34A1 Gene

MalaCards: The human disease database

(42) MalaCards diseases for SLC34A1 Gene - From: OMI, CVR, GTR, ORP, SWI, COP, and GCD

- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

NPT2A_HUMAN
  • Nephrolithiasis/osteoporosis, hypophosphatemic, 1 (NPHLOP1) [MIM:612286]: A disease characterized by decreased renal phosphate absorption, renal phosphate wasting, hypophosphatemia, hyperphosphaturia, hypercalciuria, nephrolithiasis and osteoporosis. {ECO:0000269 PubMed:12324554}. Note=The disease is caused by variants affecting the gene represented in this entry.
  • Fanconi renotubular syndrome 2 (FRTS2) [MIM:613388]: A form of Fanconi renotubular syndrome, a disease due to a generalized dysfunction of the proximal kidney tubule resulting in decreased solute and water reabsorption. Patients have polydipsia and polyuria with phosphaturia, glycosuria and aminoaciduria. They may develop hypophosphatemic rickets or osteomalacia, acidosis and a tendency toward dehydration. Some eventually develop renal insufficiency. FRTS2 inheritance is autosomal recessive. {ECO:0000269 PubMed:20335586}. Note=The disease is caused by variants affecting the gene represented in this entry.
  • Hypercalcemia, infantile, 2 (HCINF2) [MIM:616963]: An autosomal recessive form of hypercalcemia, a disorder characterized by abnormally high level of calcium in the blood, failure to thrive, vomiting, dehydration, and nephrocalcinosis. {ECO:0000269 PubMed:26047794}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for SLC34A1

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with SLC34A1: view

No data available for Genatlas for SLC34A1 Gene

Publications for SLC34A1 Gene

  1. Expression cloning of human and rat renal cortex Na/Pi cotransport. (PMID: 8327470) Magagnin S … Murer H (Proceedings of the National Academy of Sciences of the United States of America 1993) 2 3 4 22
  2. Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia. (PMID: 26047794) Schlingmann KP … Konrad M (Journal of the American Society of Nephrology : JASN 2016) 3 4 72
  3. A loss-of-function mutation in NaPi-IIa and renal Fanconi's syndrome. (PMID: 20335586) Magen D … Skorecki K (The New England journal of medicine 2010) 3 4 72
  4. Nephrolithiasis and osteoporosis associated with hypophosphatemia caused by mutations in the type 2a sodium-phosphate cotransporter. (PMID: 12324554) Prié D … Friedlander G (The New England journal of medicine 2002) 3 4 72
  5. Structure of murine and human renal type II Na+-phosphate cotransporter genes (Npt2 and NPT2). (PMID: 8693007) Hartmann CM … Tenenhouse HS (Proceedings of the National Academy of Sciences of the United States of America 1996) 2 3 22

ExternalLinks

View latest publications for SLC34A1 gene in Mastermind

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Sources for SLC34A1 Gene