Aliases for SLC2A8 Gene
External Ids for SLC2A8 Gene
Previous GeneCards Identifiers for SLC2A8 Gene
This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
GeneCards Summary for SLC2A8 Gene
SLC2A8 (Solute Carrier Family 2 Member 8) is a Protein Coding gene. Diseases associated with SLC2A8 include Endometrial Clear Cell Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. Gene Ontology (GO) annotations related to this gene include transmembrane transporter activity and glucose transmembrane transporter activity. An important paralog of this gene is SLC2A6.
UniProtKB/Swiss-Prot Summary for SLC2A8 Gene
Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Also able to mediate the transport of dehydroascorbate.