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Aliases for SLC29A1 Gene

Aliases for SLC29A1 Gene

  • Solute Carrier Family 29 Member 1 (Augustine Blood Group) 2 3 5
  • Solute Carrier Family 29 (Equilibrative Nucleoside Transporter), Member 1 2 3
  • Nucleoside Transporter, Es-Type 3 4
  • ENT1 3 4
  • Equilibrative Nitrobenzylmercaptopurine Riboside (NBMPR)-Sensitive Nucleoside Transporter 3
  • Equilibrative Nitrobenzylmercaptopurine Riboside-Sensitive Nucleoside Transporter 4
  • Solute Carrier Family 29 (Nucleoside Transporters), Member 1 3
  • Equilibrative NBMPR-Sensitive Nucleoside Transporter 4
  • Equilibrative Nucleoside Transporter 1 3
  • Solute Carrier Family 29 Member 1 4

External Ids for SLC29A1 Gene

Previous HGNC Symbols for SLC29A1 Gene

  • ENT1

Previous GeneCards Identifiers for SLC29A1 Gene

  • GC06P044189
  • GC06P044234
  • GC06P044295
  • GC06P044187
  • GC06P043909

Summaries for SLC29A1 Gene

Entrez Gene Summary for SLC29A1 Gene

  • This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for SLC29A1 Gene

SLC29A1 (Solute Carrier Family 29 Member 1 (Augustine Blood Group)) is a Protein Coding gene. Diseases associated with SLC29A1 include Periampullary Adenocarcinoma and Pancreas Adenocarcinoma. Among its related pathways are Thiopurine Pathway, Pharmacokinetics/Pharmacodynamics and Transport of vitamins, nucleosides, and related molecules. Gene Ontology (GO) annotations related to this gene include nucleoside transmembrane transporter activity. An important paralog of this gene is SLC29A2.

UniProtKB/Swiss-Prot for SLC29A1 Gene

  • Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).

Tocris Summary for SLC29A1 Gene

  • Nucleoside transporters are divided into two families: the Na+-dependent solute carrier family 28 (SLC28) and the equilibrative solute carrier family 29 (SLC29). SLC28 family transporters (CNT1, 2 and 3) display subtype-selective tissue expression patterns.

Gene Wiki entry for SLC29A1 Gene

Additional gene information for SLC29A1 Gene

No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLC29A1 Gene

Genomics for SLC29A1 Gene

GeneHancer (GH) Regulatory Elements for SLC29A1 Gene

Promoters and enhancers for SLC29A1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I044216 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 564 +3.7 3662 14.3 CLOCK MLX DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC SSRP1 SLC29A1 GTPBP2 POLH RPS2P29 ZNF318 ABCC10 YIPF3 MYMX SLC35B2 RPL34P14
GH06I044200 Enhancer 1.3 Ensembl ENCODE dbSUPER 38.3 -17.2 -17202 3.4 ARNT SIN3A TCF12 FOS ATF7 SP5 NCOA1 PPARG ZNF592 SREBF1 SLC29A1 CAPN11 HSP90AB1 NFKBIE TMEM151B SLC35B2 MRPL14 TMEM63B MYMX RN7SL811P
GH06I044255 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.7 +41.4 41439 11.9 CLOCK ZFP64 DMAP1 YBX1 IRF4 E2F8 ZNF143 ZNF263 SP3 SSRP1 SLC35B2 ABCC10 RPL34P14 ZNF318 AARS2 NFKBIE RPS2P29 POLH GTPBP2 POLR1C
GH06I044033 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 9.5 -183.9 -183903 3.6 TFAP4 MAX EBF1 CEBPG ZNF644 RAD21 ZNF48 TEAD3 SLC30A9 POLR2A NFKBIE C6orf223 VEGFA RSPH9 SLC29A1 GTPBP2 MAD2L1BP GC06P044013 LOC101929705 GC06M044069
GH06I044114 Enhancer 1.2 Ensembl ENCODE dbSUPER 10.9 -103.1 -103111 4.6 FOXA2 RARA YY1 RCOR1 SMARCA5 ZNF362 RXRA REST PPARG SMARCA4 MRPL14 CAPN11 SLC29A1 HSP90AB1 TMEM63B NFKBIE SLC35B2 CRIP3 PIR46189
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SLC29A1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SLC29A1 gene promoter:

Genomic Locations for SLC29A1 Gene

Genomic Locations for SLC29A1 Gene
chr6:44,219,505-44,234,151
(GRCh38/hg38)
Size:
14,647 bases
Orientation:
Plus strand
chr6:44,187,242-44,201,888
(GRCh37/hg19)

Genomic View for SLC29A1 Gene

Genes around SLC29A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLC29A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLC29A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLC29A1 Gene

Proteins for SLC29A1 Gene

  • Protein details for SLC29A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q99808-S29A1_HUMAN
    Recommended name:
    Equilibrative nucleoside transporter 1
    Protein Accession:
    Q99808
    Secondary Accessions:
    • B3KQV7
    • B3KQY5
    • Q5T9W9
    • Q9UJY2

    Protein attributes for SLC29A1 Gene

    Size:
    456 amino acids
    Molecular mass:
    50219 Da
    Quaternary structure:
    • Identified in a complex with STOM.

    Alternative splice isoforms for SLC29A1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLC29A1 Gene

Post-translational modifications for SLC29A1 Gene

  • Glycosylated.
  • Ubiquitination at isoforms=2239, isoforms=2249, posLast=255255, and isoforms=2356
  • Glycosylation at isoforms=248
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for SLC29A1 Gene

Domains & Families for SLC29A1 Gene

Gene Families for SLC29A1 Gene

Graphical View of Domain Structure for InterPro Entry

Q99808

UniProtKB/Swiss-Prot:

S29A1_HUMAN :
  • Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
Family:
  • Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
genes like me logo Genes that share domains with SLC29A1: view

Function for SLC29A1 Gene

Molecular function for SLC29A1 Gene

GENATLAS Biochemistry:
solute carrier family 29,member A1,equilibrative nucleoside transporter,widely distributed
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.62 mM for adenosine {ECO:0000269 PubMed:12527552}; Note=Vmax for adenosine uptake is about the same for SLC29A1 and SLC29A2.;
UniProtKB/Swiss-Prot Function:
Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).

Phenotypes From GWAS Catalog for SLC29A1 Gene

Gene Ontology (GO) - Molecular Function for SLC29A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005337 nucleoside transmembrane transporter activity TAS --
genes like me logo Genes that share ontologies with SLC29A1: view
genes like me logo Genes that share phenotypes with SLC29A1: view

Animal Models for SLC29A1 Gene

MGI Knock Outs for SLC29A1:

Animal Model Products

  • Taconic Biosciences Mouse Models for SLC29A1

miRNA for SLC29A1 Gene

miRTarBase miRNAs that target SLC29A1

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SLC29A1 Gene

Localization for SLC29A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SLC29A1 Gene

Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SLC29A1 gene
Compartment Confidence
plasma membrane 5
nucleus 3
cytosol 3
extracellular 2
mitochondrion 1
lysosome 1

Gene Ontology (GO) - Cellular Components for SLC29A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane TAS,IEA --
GO:0016020 membrane HDA,TAS 19946888
GO:0016021 integral component of membrane IEA --
GO:0016323 basolateral plasma membrane IDA,IEA 12527552
genes like me logo Genes that share ontologies with SLC29A1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for SLC29A1 Gene

Pathways & Interactions for SLC29A1 Gene

genes like me logo Genes that share pathways with SLC29A1: view

Interacting Proteins for SLC29A1 Gene

Gene Ontology (GO) - Biological Process for SLC29A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006139 nucleobase-containing compound metabolic process TAS 8986748
GO:0006810 transport IEA --
GO:0007595 lactation IEA --
GO:0015858 nucleoside transport IDA 12527552
GO:0015862 uridine transport IEA --
genes like me logo Genes that share ontologies with SLC29A1: view

No data available for SIGNOR curated interactions for SLC29A1 Gene

Drugs & Compounds for SLC29A1 Gene

(36) Drugs for SLC29A1 Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, FDA Approved Drugs, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Gemcitabine Approved Pharma Transporter, substrate Ribonucleotide reductase and DNA synthesis inhibitor, Nucleoside Analogs 2100
Ribavirin Approved Pharma Transporter, substrate 1017
Dipyridamole Approved Pharma Inhibition, Inhibitor, inhibitor Adenosine transport inhibitor 84
Cytarabine Approved, Investigational Pharma Transporter, substrate 1166
Fludarabine Approved Pharma Transporter, substrate DNA synthsis inhibitor 1231,1231

(16) Additional Compounds for SLC29A1 Gene - From: HMDB, IUPHAR, Novoseek, and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
[<sup>14</sup>C]adenosine
sodium
  • Sodium
  • Sodium ion
7440-23-5
8MDP
29491-75-6

(4) Tocris Compounds for SLC29A1 Gene

Compound Action Cas Number
8MDP Potent equilibrative nucleoside transporter (ENT) inhibitor 29491-75-6
Dilazep dihydrochloride Adenosine uptake inhibitor 20153-98-4
Dipyridamole Adenosine transport inhibitor 58-32-2
NBMPR Equilibrative nucleoside transporter 1 (ENT1) inhibitor 38048-32-7

(3) ApexBio Compounds for SLC29A1 Gene

Compound Action Cas Number
Decynium 22 977-96-8
Dilazep dihydrochloride 20153-98-4
NBMPR 38048-32-7
genes like me logo Genes that share compounds with SLC29A1: view

Drug Products

Transcripts for SLC29A1 Gene

Unigene Clusters for SLC29A1 Gene

Solute carrier family 29 (nucleoside transporters), member 1:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLC29A1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c · 11d · 11e ^ 12a ·
SP1: - - - - - - - - - - -
SP2: - - - -
SP3: - - - - - - - - - - - -
SP4: - - - - - - - - - - - -
SP5: - - - - - - - -
SP6: - -
SP7: - - - - - - -
SP8: - - - - - - -
SP9: - - - - - - - -
SP10:
SP11:
SP12:
SP13:
SP14: - - - - - - - - - - -
SP15: - - - - - -
SP16: - - - - - - - - -
SP17: - - - -
SP18:
SP19: - - - - - - - - - - - - - - - - -
SP20:
SP21:
SP22:
SP23: - - - - - - - - - - - - -
SP24: - - - - - - - - - - - -
SP25: - - - - - - - - - - -
SP26: - - - - - - - - - - - -
SP27: - - - - - - - - - - -
SP28: - - - - - - - -
SP29: - - - - - - - -
SP30: - - - - - -
SP31: - - - - - -
SP32:

ExUns: 12b · 12c · 12d · 12e · 12f · 12g · 12h ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17a · 17b ^ 18a · 18b ^ 19a · 19b ^ 20a · 20b · 20c ^ 21 ^ 22a · 22b ·
SP1: - - - - - - - -
SP2: - - - - - - - -
SP3: - - - - - - - -
SP4: - - - - - - - -
SP5: - - - - - - - -
SP6: - - - - - - - -
SP7: - - - - - -
SP8: - - - - - -
SP9: - - - - - -
SP10: - -
SP11: - - - - - -
SP12: - - - - - - - - -
SP13: - -
SP14:
SP15:
SP16: - - - - - -
SP17:
SP18: - - -
SP19: - - - - - - - - - - -
SP20:
SP21:
SP22:
SP23: - - - - - -
SP24:
SP25:
SP26:
SP27:
SP28:
SP29:
SP30:
SP31:
SP32:

Relevant External Links for SLC29A1 Gene

GeneLoc Exon Structure for
SLC29A1
ECgene alternative splicing isoforms for
SLC29A1

Expression for SLC29A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SLC29A1 Gene

Protein differential expression in normal tissues from HIPED for SLC29A1 Gene

This gene is overexpressed in Fetal Liver (10.3), Placenta (10.0), Breast (9.0), and Liver (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SLC29A1 Gene



Protein tissue co-expression partners for SLC29A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of SLC29A1 Gene:

SLC29A1

SOURCE GeneReport for Unigene cluster for SLC29A1 Gene:

Hs.25450

mRNA Expression by UniProt/SwissProt for SLC29A1 Gene:

Q99808-S29A1_HUMAN
Tissue specificity: Detected in erythrocytes (at protein level). Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.

Evidence on tissue expression from TISSUES for SLC29A1 Gene

  • Muscle(4.6)
  • Nervous system(4.6)
  • Intestine(4.5)
  • Adrenal gland(4.4)
  • Heart(2.9)
  • Liver(2.6)
  • Pancreas(2.4)
  • Kidney(2.3)
  • Lung(2.3)
  • Blood(2.1)
genes like me logo Genes that share expression patterns with SLC29A1: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLC29A1 Gene

Orthologs for SLC29A1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLC29A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLC29A1 33 34
  • 99.56 (n)
dog
(Canis familiaris)
Mammalia SLC29A1 33
  • 89.55 (n)
cow
(Bos Taurus)
Mammalia SLC29A1 33 34
  • 87.57 (n)
mouse
(Mus musculus)
Mammalia Slc29a1 33 16 34
  • 82.38 (n)
rat
(Rattus norvegicus)
Mammalia Slc29a1 33
  • 81.8 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 73 (a)
OneToMany
-- 34
  • 65 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SLC29A1 34
  • 67 (a)
OneToOne
chicken
(Gallus gallus)
Aves SLC29A1 33 34
  • 68.09 (n)
lizard
(Anolis carolinensis)
Reptilia SLC29A1 34
  • 61 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC107853 33
  • 64.41 (n)
African clawed frog
(Xenopus laevis)
Amphibia MGC68732 33
zebrafish
(Danio rerio)
Actinopterygii LOC100331439 33
  • 67.92 (n)
SLC29A1 (2 of 2) 34
  • 65 (a)
OneToMany
slc29a1a 34
  • 65 (a)
OneToMany
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.290 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009114 33
  • 50.54 (n)
fruit fly
(Drosophila melanogaster)
Insecta Ent1 33 34
  • 47.39 (n)
CG11907 35
  • 32 (a)
BEST:LD04971 35
  • 30 (a)
worm
(Caenorhabditis elegans)
Secernentea K02E11.1 35
  • 26 (a)
K09A9.3 35
  • 26 (a)
ent-2 34
  • 26 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FUN26 33
  • 43.22 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F15862g 33
  • 42.47 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU00356 33
  • 45.6 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 37 (a)
OneToMany
Species where no ortholog for SLC29A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLC29A1 Gene

ENSEMBL:
Gene Tree for SLC29A1 (if available)
TreeFam:
Gene Tree for SLC29A1 (if available)

Paralogs for SLC29A1 Gene

Paralogs for SLC29A1 Gene

(2) SIMAP similar genes for SLC29A1 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with SLC29A1: view

Variants for SLC29A1 Gene

Sequence variations from dbSNP and Humsavar for SLC29A1 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs767108156 A colorectal cancer sample 44,233,520(+) A/G coding_sequence_variant, missense_variant
VAR_036221 A colorectal cancer sample p.Ala293Thr
rs1000428509 -- 44,231,005(+) G/A intron_variant
rs1000488400 -- 44,218,369(+) G/A upstream_transcript_variant
rs1000490285 -- 44,219,638(+) A/G 5_prime_UTR_variant, genic_upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SLC29A1 Gene

Variant ID Type Subtype PubMed ID
dgv10641n54 CNV loss 21841781
nsv462936 CNV loss 19166990
nsv524398 CNV loss 19592680
nsv5282 CNV insertion 18451855
nsv603003 CNV gain 21841781

Variation tolerance for SLC29A1 Gene

Residual Variation Intolerance Score: 23.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.91; 35.58% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for SLC29A1 Gene

Human Gene Mutation Database (HGMD)
SLC29A1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLC29A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLC29A1 Gene

Disorders for SLC29A1 Gene

MalaCards: The human disease database

(7) MalaCards diseases for SLC29A1 Gene - From: HGMD, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
periampullary adenocarcinoma
pancreas adenocarcinoma
  • pancreatic adenocarcinoma
gestational diabetes
  • gdm
pancreatic ductal adenocarcinoma
  • ductal adenocarcinoma of the pancreas
diffuse idiopathic skeletal hyperostosis
  • ankylosing vertebral hyperostosis
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for SLC29A1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with SLC29A1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SLC29A1 Gene

Publications for SLC29A1 Gene

  1. Characterization of ribavirin uptake systems in human hepatocytes. (PMID: 20185188) Fukuchi Y … Chiba K (Journal of hepatology 2010) 3 22 25 58
  2. Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs. (PMID: 8986748) Griffiths M … Baldwin SA (Nature medicine 1997) 2 3 4 58
  3. Lack of the nucleoside transporter ENT1 results in the Augustine-null blood type and ectopic mineralization. (PMID: 25896650) Daniels G … Arnaud L (Blood 2015) 2 3 58
  4. Optimizing pemetrexed-gemcitabine combination in patients with advanced non-small cell lung cancer: a pharmacogenetic approach. (PMID: 21336182) De Pas TM … De Braud F (Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011) 3 25 58
  5. Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity. (PMID: 20028759) Okazaki T … Li D (Clinical cancer research : an official journal of the American Association for Cancer Research 2010) 3 44 58

Products for SLC29A1 Gene